Podosome Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
Description An actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell, contain an F-actin-rich core surrounded by a ring structure containing proteins such as vinculin and talin, and have a diameter of 0.5 mm. (Gene Ontology, GO_0002102)
External Link http://amigo.geneontology.org/amigo/term/GO:0002102
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Genes

20 proteins localized to the Podosome cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
TOX4 TOX high mobility group box family member 4 5.0
BIN2 bridging integrator 2 5.0
LPXN leupaxin 5.0
FSCN1 fascin actin-bundling protein 1 5.0
SH3PXD2A SH3 and PX domains 2A 5.0
KIF9 kinesin family member 9 5.0
AMOTL2 angiomotin like 2 5.0
GSN gelsolin 5.0
PHLDB2 pleckstrin homology-like domain, family B, member 2 5.0
PLEC plectin 4.0
FLII flightless I homolog (Drosophila) 4.0
SH3PXD2B SH3 and PX domains 2B 4.0
ERC1 ELKS/RAB6-interacting/CAST family member 1 4.0
DBNL drebrin-like 4.0
VCAM1 vascular cell adhesion molecule 1 4.0
FLNA filamin A, alpha 4.0
ADAM8 ADAM metallopeptidase domain 8 4.0
FERMT3 fermitin family member 3 4.0
SPATA13 spermatogenesis associated 13 4.0
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 3.0