Polyarthritis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C4552091
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Genes

192 genes associated with the disease Polyarthritis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACAN aggrecan
ACP3 acid phosphatase 3
ACRBP acrosin binding protein
ADCY7 adenylate cyclase 7
ALOX12 arachidonate 12-lipoxygenase
ALOX5 arachidonate 5-lipoxygenase
ANKRD55 ankyrin repeat domain 55
ANKRD9 ankyrin repeat domain 9
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
AQP9 aquaporin 9
AREG amphiregulin
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ATN1 atrophin 1
AVL9 AVL9 homolog (S. cerevisiase)
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BEND2 BEN domain containing 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTG1 B-cell translocation gene 1, anti-proliferative
BTG3 BTG family, member 3
C2ORF88 chromosome 2 open reading frame 88
C8B complement component 8, beta polypeptide
C9ORF3 chromosome 9 open reading frame 3
C9ORF72 chromosome 9 open reading frame 72
CALD1 caldesmon 1
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CARD14 caspase recruitment domain family, member 14
CD14 CD14 molecule
CD247 CD247 molecule
CD40LG CD40 ligand
CD69 CD69 molecule
CD83 CD83 molecule
CD8B CD8b molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CLU clusterin
CMTM2 CKLF-like MARVEL transmembrane domain containing 2
COL2A1 collagen, type II, alpha 1
COPA coatomer protein complex, subunit alpha
CPT2 carnitine palmitoyltransferase 2
CREM cAMP responsive element modulator
CRP C-reactive protein, pentraxin-related
CRYGD crystallin, gamma D
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSK cathepsin K
CTTN cortactin
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
DAPK1 death-associated protein kinase 1
DDIT3 DNA-damage-inducible transcript 3
DMP1 dentin matrix acidic phosphoprotein 1
DNASE2 deoxyribonuclease II, lysosomal
DUSP1 dual specificity phosphatase 1
DUSP2 dual specificity phosphatase 2
DUSP4 dual specificity phosphatase 4
DYSF dysferlin
EGF epidermal growth factor
EGR1 early growth response 1
ELF2 E74-like factor 2 (ets domain transcription factor)
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ETNK1 ethanolamine kinase 1
ETV6 ets variant 6
FAM20A family with sequence similarity 20, member A
FAXDC2 fatty acid hydroxylase domain containing 2
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCHSD2 FCH and double SH3 domains 2
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL2 FOS-like antigen 2
FOXP1 forkhead box P1
GADD45A growth arrest and DNA-damage-inducible, alpha
GMPR guanosine monophosphate reductase
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GP1BB glycoprotein Ib (platelet), beta polypeptide
GPI glucose-6-phosphate isomerase
HBEGF heparin-binding EGF-like growth factor
HERPUD2 HERPUD family member 2
HIST1H2AE histone cluster 1, H2ae
HIST1H2BG histone cluster 1, H2bg
HK1 hexokinase 1
HLA-A major histocompatibility complex, class I, A
HLA-C major histocompatibility complex, class I, C
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HP haptoglobin
HSPA14 heat shock 70kDa protein 14
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IGF1R insulin-like growth factor 1 receptor
IL10 interleukin 10
IL17A interleukin 17A
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL23A interleukin 23, alpha subunit p19
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IRF5 interferon regulatory factor 5
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGB5 integrin, beta 5
JMJD1C jumonji domain containing 1C
JUN jun proto-oncogene
KAT6B K(lysine) acetyltransferase 6B
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KLF4 Kruppel-like factor 4 (gut)
KRAS Kirsten rat sarcoma viral oncogene homolog
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
LPP LIM domain containing preferred translocation partner in lipoma
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
LTA lymphotoxin alpha
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAML2 mastermind-like 2 (Drosophila)
MAP2 microtubule-associated protein 2
MAPK1 mitogen-activated protein kinase 1
MBL2 mannose-binding lectin (protein C) 2, soluble
MEFV Mediterranean fever
MEX3C mex-3 RNA binding family member C
MMP1 matrix metallopeptidase 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP3 matrix metallopeptidase 3
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
MSN moesin
MTSS1 metastasis suppressor 1
MYZAP myocardial zonula adherens protein
NDEL1 nudE neurodevelopment protein 1-like 1
NLRP1 NLR family, pyrin domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRG1 neuregulin 1
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OR10A4 olfactory receptor, family 10, subfamily A, member 4
OSM oncostatin M
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PDCD1 programmed cell death 1
PER1 period circadian clock 1
PGM5 phosphoglucomutase 5
PLAUR plasminogen activator, urokinase receptor
PLK2 polo-like kinase 2
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PRORP protein only RNase P catalytic subunit
PROS1 protein S (alpha)
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PTH parathyroid hormone
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
R3HDM2 R3H domain containing 2
RASGEF1B RasGEF domain family, member 1B
RBM45 RNA binding motif protein 45
RBM47 RNA binding motif protein 47
RERE arginine-glutamic acid dipeptide (RE) repeats
RHOBTB1 Rho-related BTB domain containing 1
RNF103 ring finger protein 103
RNPC3 RNA-binding region (RNP1, RRM) containing 3
RPS19 ribosomal protein S19
SH3BGRL2 SH3 domain binding glutamate-rich protein like 2
SHOC2 soc-2 suppressor of clear homolog (C. elegans)
SIK1 salt-inducible kinase 1
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SMAD3 SMAD family member 3
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
STAB1 stabilin 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STIM1 stromal interaction molecule 1
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TFDP1 transcription factor Dp-1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
THBS1 thrombospondin 1
TNF tumor necrosis factor
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNIK TRAF2 and NCK interacting kinase
TRAF1 TNF receptor-associated factor 1
TREML1 triggering receptor expressed on myeloid cells-like 1
TTLL5 tubulin tyrosine ligase-like family member 5
TUBB2A tubulin, beta 2A class IIa
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBE3C ubiquitin protein ligase E3C
UHRF1BP1L UHRF1 binding protein 1-like
VCAN versican
VTCN1 V-set domain containing T cell activation inhibitor 1
WASF3 WAS protein family, member 3
WWOX WW domain containing oxidoreductase
ZFAND3 zinc finger, AN1-type domain 3
ZFC3H1 zinc finger, C3H1-type containing
ZFP36 ZFP36 ring finger protein