Polycystic Kidney Disease Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An autosomal dominant disease characterized by the presence of multiple cysts located_in the kidney resulting from ciliopathy that disrupts the function of primary cilium. (Human Disease Ontology, DOID_898)
External Link https://www.disgenet.org/browser/0/1/0/C3149841
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Genes

43 genes associated with the disease Polycystic Kidney Disease in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACLY ATP citrate lyase
ALB albumin
APRT adenine phosphoribosyltransferase
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
CCNF cyclin F
CD36 CD36 molecule (thrombospondin receptor)
CTCF CCCTC-binding factor (zinc finger protein)
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11
DOCK3 dedicator of cytokinesis 3
DZIP1L DAZ interacting zinc finger protein 1-like
EFNB2 ephrin-B2
EGR1 early growth response 1
FASN fatty acid synthase
FJX1 four jointed box 1 (Drosophila)
GANAB glucosidase, alpha; neutral AB
GFER growth factor, augmenter of liver regeneration
HBA1 hemoglobin, alpha 1
HBA2 hemoglobin, alpha 2
HDAC7 histone deacetylase 7
HNF1B HNF1 homeobox B
IL6 interleukin 6
KDR kinase insert domain receptor
KIF3A kinesin family member 3A
MED1 mediator complex subunit 1
MFAP1 microfibrillar-associated protein 1
NOS3 nitric oxide synthase 3 (endothelial cell)
NPS neuropeptide S
PCNA proliferating cell nuclear antigen
PDHX pyruvate dehydrogenase complex, component X
PEBP1 phosphatidylethanolamine binding protein 1
PGP phosphoglycolate phosphatase
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKD2 polycystic kidney disease 2 (autosomal dominant)
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRKD1 protein kinase D1
SMYD2 SET and MYND domain containing 2
TNF tumor necrosis factor
TOP2B topoisomerase (DNA) II beta 180kDa
TOPBP1 topoisomerase (DNA) II binding protein 1
TSC2 tuberous sclerosis 2
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
VEGFA vascular endothelial growth factor A