Polycystic Ovary Syndrome Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A complex disorder characterized by infertility, HIRSUTISM; OBESITY; and various menstrual disturbances such as OLIGOMENORRHEA; AMENORRHEA; ANOVULATION. Polycystic ovary syndrome is usually associated with bilateral enlarged ovaries studded with atretic follicles, not with cysts. The term, polycystic ovary, is misleading. (Experimental Factor Ontology, EFO_0000660)
External Link https://www.disgenet.org/browser/0/1/0/C0032460
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Genes

904 genes associated with the disease Polycystic Ovary Syndrome in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ACACA acetyl-CoA carboxylase alpha
ACAN aggrecan
ACE angiotensin I converting enzyme
ACTA1 actin, alpha 1, skeletal muscle
ACTB actin, beta
ACVR1 activin A receptor, type I
ACVR2A activin A receptor, type IIA
ACVR2B activin A receptor, type IIB
ADA adenosine deaminase
ADA2 adenosine deaminase 2
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif, 19
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
ADARB1 adenosine deaminase, RNA-specific, B1
ADGRD2 adhesion G protein-coupled receptor D2
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIPOR1 adiponectin receptor 1
ADIPOR2 adiponectin receptor 2
ADM adrenomedullin
ADRA1A adrenoceptor alpha 1A
ADRA1B adrenoceptor alpha 1B
ADRA1D adrenoceptor alpha 1D
ADRA2B adrenoceptor alpha 2B
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
AFM afamin
AGER advanced glycosylation end product-specific receptor
AGO2 argonaute RISC catalytic component 2
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AGRP agouti related neuropeptide
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AHSG alpha-2-HS-glycoprotein
AKAP8 A kinase (PRKA) anchor protein 8
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALB albumin
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALMS1 Alstrom syndrome protein 1
AMH anti-Mullerian hormone
AMHR2 anti-Mullerian hormone receptor, type II
ANGPTL1 angiopoietin-like 1
ANGPTL2 angiopoietin-like 2
ANGPTL6 angiopoietin-like 6
ANGPTL8 angiopoietin like 8
ANLN anillin, actin binding protein
ANTXR2 anthrax toxin receptor 2
ANXA5 annexin A5
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APLN apelin
APOA1 apolipoprotein A-I
APOB apolipoprotein B
APOC1 apolipoprotein C-I
APOE apolipoprotein E
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
APRT adenine phosphoribosyltransferase
AQP7 aquaporin 7
AQP8 aquaporin 8
AQP9 aquaporin 9
AR androgen receptor
AREG amphiregulin
ARHGAP23 Rho GTPase activating protein 23
ARHGAP30 Rho GTPase activating protein 30
ARHGAP9 Rho GTPase activating protein 9
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARID1B AT rich interactive domain 1B (SWI1-like)
ARID4B AT rich interactive domain 4B (RBP1-like)
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARSD arylsulfatase D
ARTN artemin
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATAD1 ATPase family, AAA domain containing 1
ATF1 activating transcription factor 1
ATF4 activating transcription factor 4
ATF6 activating transcription factor 6
ATM ATM serine/threonine kinase
ATN1 atrophin 1
ATP5F1B ATP synthase F1 subunit beta
AVP arginine vasopressin
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BAAT bile acid CoA:amino acid N-acyltransferase
BAX BCL2-associated X protein
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCAR3 breast cancer anti-estrogen resistance 3
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL2 B-cell CLL/lymphoma 2
BCL2A1 BCL2-related protein A1
BCO1 beta-carotene oxygenase 1
BDNF brain-derived neurotrophic factor
BEST1 bestrophin 1
BGLAP bone gamma-carboxyglutamate (gla) protein
BHMT betaine--homocysteine S-methyltransferase
BLK BLK proto-oncogene, Src family tyrosine kinase
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3
BMP15 bone morphogenetic protein 15
BMP4 bone morphogenetic protein 4
BMP6 bone morphogenetic protein 6
BMPR1A bone morphogenetic protein receptor, type IA
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BMS1 BMS1 ribosome biogenesis factor
BRD2 bromodomain containing 2
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
C12ORF66 chromosome 12 open reading frame 66
C19ORF68 chromosome 19 open reading frame 68
C1QL3 complement component 1, q subcomponent-like 3
C1QTNF3 C1q and tumor necrosis factor related protein 3
C3 complement component 3
C9ORF3 chromosome 9 open reading frame 3
CALCA calcitonin-related polypeptide alpha
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CAPN10 calpain 10
CAPN5 calpain 5
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CAVIN1 caveolae associated protein 1
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CBS cystathionine-beta-synthase
CBX2 chromobox homolog 2
CCDC176 coiled-coil domain containing 176
CCDC91 coiled-coil domain containing 91
CCHCR1 coiled-coil alpha-helical rod protein 1
CCK cholecystokinin
CCL2 chemokine (C-C motif) ligand 2
CCN1 cellular communication network factor 1
CCN2 cellular communication network factor 2
CCNB1 cyclin B1
CCND2 cyclin D2
CCNE2 cyclin E2
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD44 CD44 molecule (Indian blood group)
CD59 CD59 molecule, complement regulatory protein
CD68 CD68 molecule
CD69 CD69 molecule
CDC6 cell division cycle 6
CDH15 cadherin 15, type 1, M-cadherin (myotubule)
CDK2 cyclin-dependent kinase 2
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDX2 caudal type homeobox 2
CEP55 centrosomal protein 55kDa
CFAP97 cilia and flagella associated protein 97
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CGA glycoprotein hormones, alpha polypeptide
CGB chorionic gonadotropin, beta polypeptide
CGB5 chorionic gonadotropin, beta polypeptide 5
CGB8 chorionic gonadotropin, beta polypeptide 8
CHM choroideremia (Rab escort protein 1)
CHPT1 choline phosphotransferase 1
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CIB1 calcium and integrin binding 1 (calmyrin)
CIDEC cell death-inducing DFFA-like effector c
CKS2 CDC28 protein kinase regulatory subunit 2
CLDN4 claudin 4
CLIP2 CAP-GLY domain containing linker protein 2
CMTR2 cap methyltransferase 2
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CNR1 cannabinoid receptor 1 (brain)
CNTROB centrobin, centrosomal BRCA2 interacting protein
COMT catechol-O-methyltransferase
COPA coatomer protein complex, subunit alpha
CORIN corin, serine peptidase
COX2
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CPA1 carboxypeptidase A1 (pancreatic)
CPB2 carboxypeptidase B2 (plasma)
CPT1A carnitine palmitoyltransferase 1A (liver)
CPT2 carnitine palmitoyltransferase 2
CRB1 crumbs family member 1, photoreceptor morphogenesis associated
CREBBP CREB binding protein
CRISP2 cysteine-rich secretory protein 2
CRP C-reactive protein, pentraxin-related
CSF3 colony stimulating factor 3 (granulocyte)
CTF1 cardiotrophin 1
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTRL chymotrypsin-like
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL8 chemokine (C-X-C motif) ligand 8
CYBB cytochrome b-245, beta polypeptide
CYC1 cytochrome c-1
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DACT3 dishevelled-binding antagonist of beta-catenin 3
DAPK1 death-associated protein kinase 1
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DBP D site of albumin promoter (albumin D-box) binding protein
DCBLD2 discoidin, CUB and LCCL domain containing 2
DCN decorin
DCTN4 dynactin 4 (p62)
DCTN6 dynactin 6
DDIT3 DNA-damage-inducible transcript 3
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DENND1A DENN/MADD domain containing 1A
DESI1 desumoylating isopeptidase 1
DHCR7 7-dehydrocholesterol reductase
DHH desert hedgehog
DHRS11 dehydrogenase/reductase (SDR family) member 11
DHRS9 dehydrogenase/reductase (SDR family) member 9
DICER1 dicer 1, ribonuclease type III
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLG4 discs, large homolog 4 (Drosophila)
DMAP1 DNA methyltransferase 1 associated protein 1
DMD dystrophin
DMRT1 doublesex and mab-3 related transcription factor 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DOCK1 dedicator of cytokinesis 1
DPP4 dipeptidyl-peptidase 4
DRAM2 DNA-damage regulated autophagy modulator 2
DRD3 dopamine receptor D3
DSCC1 DNA replication and sister chromatid cohesion 1
ECI1 enoyl-CoA delta isomerase 1
EDN1 endothelin 1
EDN2 endothelin 2
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGR3 early growth response 3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ELANE elastase, neutrophil expressed
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ELMO1 engulfment and cell motility 1
ELN elastin
EMSY EMSY transcriptional repressor, BRCA2 interacting
ENHO energy homeostasis associated
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPHA7 EPH receptor A7
EPHB2 EPH receptor B2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EPO erythropoietin
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ERCC2 excision repair cross-complementation group 2
EREG epiregulin
ERRFI1 ERBB receptor feedback inhibitor 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
F13A1 coagulation factor XIII, A1 polypeptide
F2 coagulation factor II (thrombin)
F3 coagulation factor III (thromboplastin, tissue factor)
F5 coagulation factor V (proaccelerin, labile factor)
FAAH fatty acid amide hydrolase
FABP1 fatty acid binding protein 1, liver
FABP4 fatty acid binding protein 4, adipocyte
FADD Fas (TNFRSF6)-associated via death domain
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FAM132A family with sequence similarity 132, member A
FAM84A family with sequence similarity 84, member A
FAS Fas cell surface death receptor
FAT1 FAT atypical cadherin 1
FBLN1 fibulin 1
FBN1 fibrillin 1
FBN3 fibrillin 3
FBRS fibrosin
FBXO44 F-box protein 44
FBXO8 F-box protein 8
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FEM1A fem-1 homolog a (C. elegans)
FEM1B fem-1 homolog b (C. elegans)
FEM1C fem-1 homolog c (C. elegans)
FGF13 fibroblast growth factor 13
FGF18 fibroblast growth factor 18
FGF19 fibroblast growth factor 19
FGF2 fibroblast growth factor 2 (basic)
FGF21 fibroblast growth factor 21
FGF23 fibroblast growth factor 23
FGG fibrinogen gamma chain
FKBP4 FK506 binding protein 4, 59kDa
FLAD1 flavin adenine dinucleotide synthetase 1
FLNA filamin A, alpha
FLT1 fms-related tyrosine kinase 1
FLT4 fms-related tyrosine kinase 4
FLVCR1 feline leukemia virus subgroup C cellular receptor 1
FMR1 fragile X mental retardation 1
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FOXP3 forkhead box P3
FSHB follicle stimulating hormone, beta polypeptide
FSHR follicle stimulating hormone receptor
FST follistatin
FTMT ferritin mitochondrial
FTO fat mass and obesity associated
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
FZD3 frizzled class receptor 3
G6PC glucose-6-phosphatase, catalytic subunit
GAB1 GRB2-associated binding protein 1
GABARAP GABA(A) receptor-associated protein
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA4 GATA binding protein 4
GATA6 GATA binding protein 6
GC group-specific component (vitamin D binding protein)
GCG glucagon
GCK glucokinase (hexokinase 4)
GCKR glucokinase (hexokinase 4) regulator
GDE1 glycerophosphodiester phosphodiesterase 1
GDF9 growth differentiation factor 9
GGT1 gamma-glutamyltransferase 1
GH1 growth hormone 1
GHR growth hormone receptor
GHRL ghrelin/obestatin prepropeptide
GIP gastric inhibitory polypeptide
GLIPR1 GLI pathogenesis-related 1
GLP1R glucagon-like peptide 1 receptor
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNAS GNAS complex locus
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GNRHR gonadotropin-releasing hormone receptor
GP1BB glycoprotein Ib (platelet), beta polypeptide
GPR3 G protein-coupled receptor 3
GPR83 G protein-coupled receptor 83
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GPX1 glutathione peroxidase 1
GPX3 glutathione peroxidase 3
GREB1 growth regulation by estrogen in breast cancer 1
GREM1 gremlin 1, DAN family BMP antagonist
GREM2 gremlin 2, DAN family BMP antagonist
GSK3B glycogen synthase kinase 3 beta
GSTK1 glutathione S-transferase kappa 1
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
GTF2I general transcription factor IIi
GTF2IRD1 GTF2I repeat domain containing 1
GYS2 glycogen synthase 2 (liver)
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HACD1 3-hydroxyacyl-CoA dehydratase 1
HAMP hepcidin antimicrobial peptide
HAS1 hyaluronan synthase 1
HAS2 hyaluronan synthase 2
HAS3 hyaluronan synthase 3
HDAC3 histone deacetylase 3
HELLS helicase, lymphoid-specific
HHEX hematopoietically expressed homeobox
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGA2 high mobility group AT-hook 2
HMGB1 high mobility group box 1
HMGB2 high mobility group box 2
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMMR hyaluronan-mediated motility receptor (RHAMM)
HMOX1 heme oxygenase 1
HNF1A HNF1 homeobox A
HNF4A hepatocyte nuclear factor 4, alpha
HOOK3 hook microtubule-tethering protein 3
HOXA10 homeobox A10
HP haptoglobin
HPGDS hematopoietic prostaglandin D synthase
HRAS Harvey rat sarcoma viral oncogene homolog
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HSD17B13 hydroxysteroid (17-beta) dehydrogenase 13
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA1A heat shock 70kDa protein 1A
HSPA1B heat shock 70kDa protein 1B
HSPA4 heat shock 70kDa protein 4
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPB1 heat shock 27kDa protein 1
HSPB2 heat shock 27kDa protein 2
HSPB3 heat shock 27kDa protein 3
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
IAPP islet amyloid polypeptide
IARS1 isoleucyl-tRNA synthetase 1
ICAM1 intercellular adhesion molecule 1
IDE insulin-degrading enzyme
IFI27 interferon, alpha-inducible protein 27
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGFBP1 insulin-like growth factor binding protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP4 insulin-like growth factor binding protein 4
IGFBP6 insulin-like growth factor binding protein 6
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL10 interleukin 10
IL11 interleukin 11
IL17A interleukin 17A
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL2RA interleukin 2 receptor, alpha
IL32 interleukin 32
IL34 interleukin 34
IL6 interleukin 6
IL7 interleukin 7
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
INHA inhibin, alpha
INHBA inhibin, beta A
INHBB inhibin, beta B
INS insulin
INSIG2 insulin induced gene 2
INSL3 insulin-like 3 (Leydig cell)
INSL5 insulin-like 5
INSL6 insulin-like 6
INSR insulin receptor
IQCC IQ motif containing C
IRF1 interferon regulatory factor 1
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
ISG20 interferon stimulated exonuclease gene 20kDa
ISYNA1 inositol-3-phosphate synthase 1
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB5 integrin, beta 5
ITK IL2-inducible T-cell kinase
ITLN1 intelectin 1 (galactofuranose binding)
JAK2 Janus kinase 2
JSRP1 junctional sarcoplasmic reticulum protein 1
JUN jun proto-oncogene
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIF7 kinesin family member 7
KISS1 KiSS-1 metastasis-suppressor
KISS1R KISS1 receptor
KITLG KIT ligand
KL klotho
KLK3 kallikrein-related peptidase 3
KNG1 kininogen 1
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast)
KRT16 keratin 16, type I
KRT3 keratin 3, type II
LALBA lactalbumin, alpha-
LARP4 La ribonucleoprotein domain family, member 4
LCN2 lipocalin 2
LCT lactase
LDLR low density lipoprotein receptor
LEAP2 liver expressed antimicrobial peptide 2
LEP leptin
LEPR leptin receptor
LGALS3 lectin, galactoside-binding, soluble, 3
LGR6 leucine-rich repeat containing G protein-coupled receptor 6
LHB luteinizing hormone beta polypeptide
LHCGR luteinizing hormone/choriogonadotropin receptor
LIF leukemia inhibitory factor
LIFR leukemia inhibitory factor receptor alpha
LIMK1 LIM domain kinase 1
LIN28B lin-28 homolog B (C. elegans)
LIPE lipase, hormone-sensitive
LMNA lamin A/C
LMNB2 lamin B2
LOC102724560 cystathionine beta-synthase
LOX lysyl oxidase
LPA lipoprotein, Lp(a)
LPCAT2 lysophosphatidylcholine acyltransferase 2
LPIN1 lipin 1
LPL lipoprotein lipase
LPP LIM domain containing preferred translocation partner in lipoma
LRP5 low density lipoprotein receptor-related protein 5
LRRC16B leucine rich repeat containing 16B
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LTK leukocyte receptor tyrosine kinase
LUM lumican
LYN LYN proto-oncogene, Src family tyrosine kinase
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAGEA11 melanoma antigen family A11
MANEA mannosidase, endo-alpha
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K15 mitogen-activated protein kinase kinase kinase 15
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAPRE1 microtubule-associated protein, RP/EB family, member 1
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MC3R melanocortin 3 receptor
MC4R melanocortin 4 receptor
MCF2L2 MCF.2 cell line derived transforming sequence-like 2
MCM2 minichromosome maintenance complex component 2
MCM7 minichromosome maintenance complex component 7
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECP2 methyl CpG binding protein 2
MEF2A myocyte enhancer factor 2A
MELTF melanotransferrin
MEP1A meprin A, alpha (PABA peptide hydrolase)
MFAP1 microfibrillar-associated protein 1
MGAT5B mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIOX myo-inositol oxygenase
MIP major intrinsic protein of lens fiber
MKRN3 makorin ring finger protein 3
MMP1 matrix metallopeptidase 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP26 matrix metallopeptidase 26
MMP9 matrix metallopeptidase 9
MMRN1 multimerin 1
MOK MOK protein kinase
MORN1 MORN repeat containing 1
MPG N-methylpurine-DNA glycosylase
MPO myeloperoxidase
MRO maestro
MSC musculin
MSTN myostatin
MSX1 msh homeobox 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTNR1A melatonin receptor 1A
MTNR1B melatonin receptor 1B
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MUC1 mucin 1, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUSK muscle, skeletal, receptor tyrosine kinase
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NAMPT nicotinamide phosphoribosyltransferase
NANOS3 nanos homolog 3 (Drosophila)
NANS N-acetylneuraminic acid synthase
NBN nibrin
NCF1 neutrophil cytosolic factor 1
NCOA3 nuclear receptor coactivator 3
NCOA4 nuclear receptor coactivator 4
NCOR1 nuclear receptor corepressor 1
NEGR1 neuronal growth regulator 1
NEIL2 nei endonuclease VIII-like 2 (E. coli)
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NGF nerve growth factor (beta polypeptide)
NGFR nerve growth factor receptor
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies)
NLRP1 NLR family, pyrin domain containing 1
NMNAT3 nicotinamide nucleotide adenylyltransferase 3
NNMT nicotinamide N-methyltransferase
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NOP53 NOP53 ribosome biogenesis factor
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NOTCH3 notch 3
NPB neuropeptide B
NPPB natriuretic peptide B
NPPC natriuretic peptide C
NPR2 natriuretic peptide receptor 2
NQO1 NAD(P)H dehydrogenase, quinone 1
NR0B1 nuclear receptor subfamily 0, group B, member 1
NR0B2 nuclear receptor subfamily 0, group B, member 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR5A1 nuclear receptor subfamily 5, group A, member 1
NRG1 neuregulin 1
NRIP1 nuclear receptor interacting protein 1
NUCB2 nucleobindin 2
NUP62 nucleoporin 62kDa
ODF3B outer dense fiber of sperm tails 3B
OR10A4 olfactory receptor, family 10, subfamily A, member 4
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene)
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PAEP progestagen-associated endometrial protein
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PAX6 paired box 6
PBK PDZ binding kinase
PCLAF PCNA clamp associated factor
PCNA proliferating cell nuclear antigen
PCSK1 proprotein convertase subtilisin/kexin type 1
PCSK9 proprotein convertase subtilisin/kexin type 9
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDE8A phosphodiesterase 8A
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDLIM4 PDZ and LIM domain 4
PDPK1 3-phosphoinositide dependent protein kinase 1
PEA15 phosphoprotein enriched in astrocytes 15
PF4 platelet factor 4
PGR progesterone receptor
PHB prohibitin
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLAT plasminogen activator, tissue
PLAUR plasminogen activator, urokinase receptor
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
PLG plasminogen
PLIN1 perilipin 1
PLXNA2 plexin A2
PMEL premelanosome protein
PNN pinin, desmosome associated protein
PNPLA2 patatin-like phospholipase domain containing 2
PNPLA3 patatin-like phospholipase domain containing 3
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
POMC proopiomelanocortin
PON1 paraoxonase 1
PON2 paraoxonase 2
POR P450 (cytochrome) oxidoreductase
POSTN periostin, osteoblast specific factor
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PPP1R12C protein phosphatase 1, regulatory subunit 12C
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PPP1R3A protein phosphatase 1, regulatory subunit 3A
PPP5C protein phosphatase 5, catalytic subunit
PPT1 palmitoyl-protein thioesterase 1
PRDX1 peroxiredoxin 1
PRDX3 peroxiredoxin 3
PRDX4 peroxiredoxin 4
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKAG3 protein kinase, AMP-activated, gamma 3 non-catalytic subunit
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKD2 protein kinase D2
PRL prolactin
PRLR prolactin receptor
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROK1 prokineticin 1
PRPF31 pre-mRNA processing factor 31
PRSS55 protease, serine, 55
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTAFR platelet-activating factor receptor
PTBP1 polypyrimidine tract binding protein 1
PTBP2 polypyrimidine tract binding protein 2
PTCRA pre T-cell antigen receptor alpha
PTEN phosphatase and tensin homolog
PTGDR prostaglandin D2 receptor (DP)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTPA protein phosphatase 2 phosphatase activator
PTRH2 peptidyl-tRNA hydrolase 2
PTX3 pentraxin 3, long
PWWP2B PWWP domain containing 2B
PYCARD PYD and CARD domain containing
PYY peptide YY
RAB2A RAB2A, member RAS oncogene family
RAB5B RAB5B, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RACGAP1 Rac GTPase activating protein 1
RAD50 RAD50 homolog (S. cerevisiae)
RAD54B RAD54 homolog B (S. cerevisiae)
RAPSN receptor-associated protein of the synapse
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RASL10B RAS-like, family 10, member B
RB1 retinoblastoma 1
RBM45 RNA binding motif protein 45
RBP4 retinol binding protein 4, plasma
REN renin
RENBP renin binding protein
RETN resistin
REXO1 REX1, RNA exonuclease 1 homolog (S. cerevisiae)
RFC2 replication factor C (activator 1) 2, 40kDa
RHOG ras homolog family member G
RHPN1 rhophilin, Rho GTPase binding protein 1
RNF6 ring finger protein (C3H2C3 type) 6
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
ROR1 receptor tyrosine kinase-like orphan receptor 1
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPL3 ribosomal protein L3
RPL36A ribosomal protein L36a
RPL37A ribosomal protein L37a
RPS26 ribosomal protein S26
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RRM2 ribonucleotide reductase M2
RUNX2 runt-related transcription factor 2
RUNX3 runt-related transcription factor 3
S100A1 S100 calcium binding protein A1
S100A4 S100 calcium binding protein A4
S100A6 S100 calcium binding protein A6
S100A7A S100 calcium binding protein A7A
S100B S100 calcium binding protein B
S100P S100 calcium binding protein P
SAP30L SAP30-like
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SCT secretin
SELENBP1 selenium binding protein 1
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SEPP1 selenoprotein P, plasma, 1
SERBP1 SERPINE1 mRNA binding protein 1
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SET SET nuclear proto-oncogene
SETD2 SET domain containing 2
SFRP4 secreted frizzled-related protein 4
SFRP5 secreted frizzled-related protein 5
SFTPC surfactant protein C
SFXN1 sideroflexin 1
SGK3 serum/glucocorticoid regulated kinase family, member 3
SGSM3 small G protein signaling modulator 3
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SHBG sex hormone-binding globulin
SIRT1 sirtuin 1
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC2A4RG SLC2A4 regulator
SLC30A8 solute carrier family 30 (zinc transporter), member 8
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC35G1 solute carrier family 35, member G1
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC47A2 solute carrier family 47 (multidrug and toxin extrusion), member 2
SLC5A11 solute carrier family 5 (sodium/inositol cotransporter), member 11
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLCO6A1 solute carrier organic anion transporter family, member 6A1
SLPI secretory leukocyte peptidase inhibitor
SMAD1 SMAD family member 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMAD6 SMAD family member 6
SMAD7 SMAD family member 7
SNAI1 snail family zinc finger 1
SOCS3 suppressor of cytokine signaling 3
SOD2 superoxide dismutase 2, mitochondrial
SORBS1 sorbin and SH3 domain containing 1
SORCS1 sortilin-related VPS10 domain containing receptor 1
SOX15 SRY (sex determining region Y)-box 15
SOX3 SRY (sex determining region Y)-box 3
SOX5 SRY (sex determining region Y)-box 5
SOX9 SRY (sex determining region Y)-box 9
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPATA21 spermatogenesis associated 21
SPP1 secreted phosphoprotein 1
SPPL3 signal peptide peptidase like 3
SPTBN4 spectrin, beta, non-erythrocytic 4
SPZ1 spermatogenic leucine zipper 1
SQSTM1 sequestosome 1
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
SREBF1 sterol regulatory element binding transcription factor 1
SREBF2 sterol regulatory element binding transcription factor 2
SRF serum response factor (c-fos serum response element-binding transcription factor)
SRSF10 serine/arginine-rich splicing factor 10
SRY sex determining region Y
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STAR steroidogenic acute regulatory protein
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STC1 stanniocalcin 1
STK11 serine/threonine kinase 11
STK26 serine/threonine protein kinase 26
STON1-GTF2A1L STON1-GTF2A1L readthrough
STOX1 storkhead box 1
STS steroid sulfatase (microsomal), isozyme S
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
SUOX sulfite oxidase
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAC1 tachykinin, precursor 1
TAC3 tachykinin 3
TACR3 tachykinin receptor 3
TADA1 transcriptional adaptor 1
TAS2R13 taste receptor, type 2, member 13
TBC1D4 TBC1 domain family, member 4
TBL2 transducin (beta)-like 2
TBX1 T-box 1
TCF15 transcription factor 15 (basic helix-loop-helix)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TEAD2 TEA domain family member 2
TFAM transcription factor A, mitochondrial
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFBR1 transforming growth factor, beta receptor 1
TH tyrosine hydroxylase
THADA thyroid adenoma associated
THAP3 THAP domain containing, apoptosis associated protein 3
THBS1 thrombospondin 1
TICAM2 toll-like receptor adaptor molecule 2
TICRR TOPBP1-interacting checkpoint and replication regulator
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP3 TIMP metallopeptidase inhibitor 3
TIMP4 TIMP metallopeptidase inhibitor 4
TLE5 TLE family member 5, transcriptional modulator
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TM4SF4 transmembrane 4 L six family member 4
TMED7 transmembrane emp24 protein transport domain containing 7
TMED7-TICAM2 TMED7-TICAM2 readthrough
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2
TMEM120B transmembrane protein 120B
TMEM151A transmembrane protein 151A
TMEM151B transmembrane protein 151B
TMEM18 transmembrane protein 18
TMF1 TATA element modulatory factor 1
TNC tenascin C
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNFSF12-TNFSF13 TNFSF12-TNFSF13 readthrough
TNPO2 transportin 2
TNRC6B trinucleotide repeat containing 6B
TONSL tonsoku-like, DNA repair protein
TOP1 topoisomerase (DNA) I
TOP2A topoisomerase (DNA) II alpha 170kDa
TOR2A torsin family 2, member A
TOX3 TOX high mobility group box family member 3
TP53 tumor protein p53
TPD52 tumor protein D52
TPM1 tropomyosin 1 (alpha)
TPM2 tropomyosin 2 (beta)
TPT1 tumor protein, translationally-controlled 1
TRIB3 tribbles pseudokinase 3
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSPAN31 tetraspanin 31
TTK TTK protein kinase
TTLL9 tubulin tyrosine ligase-like family member 9
UBE2H ubiquitin-conjugating enzyme E2H
UCN2 urocortin 2
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
USP34 ubiquitin specific peptidase 34
VCAM1 vascular cell adhesion molecule 1
VCAN versican
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIM vimentin
VIP vasoactive intestinal peptide
WFS1 Wolfram syndrome 1 (wolframin)
WISP1 WNT1 inducible signaling pathway protein 1
WNT1 wingless-type MMTV integration site family, member 1
WNT2B wingless-type MMTV integration site family, member 2B
WNT3A wingless-type MMTV integration site family, member 3A
WNT4 wingless-type MMTV integration site family, member 4
WNT5A wingless-type MMTV integration site family, member 5A
WNT8B wingless-type MMTV integration site family, member 8B
WT1 Wilms tumor 1
XK X-linked Kx blood group
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
YAP1 Yes-associated protein 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZBTB16 zinc finger and BTB domain containing 16
ZGLP1 zinc finger, GATA-like protein 1
ZMYM5 zinc finger, MYM-type 5
ZNF205 zinc finger protein 205
ZNF217 zinc finger protein 217
ZNF410 zinc finger protein 410
ZNF430 zinc finger protein 430
ZP4 zona pellucida glycoprotein 4