Polydactyly Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
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Genes

804 genes co-occuring with the disease Polydactyly in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
LMBR1 limb development membrane protein 1 3.53
GLI3 GLI family zinc finger 3 3.459
BBS1 Bardet-Biedl syndrome 1 3.434
SHH sonic hedgehog 3.296
BBS2 Bardet-Biedl syndrome 2 3.288
ZP2 zona pellucida glycoprotein 2 (sperm receptor) 3.278
BBS4 Bardet-Biedl syndrome 4 3.217
BBS10 Bardet-Biedl syndrome 10 3.215
BBS7 Bardet-Biedl syndrome 7 3.193
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 3.174
EVC2 Ellis van Creveld syndrome 2 3.138
BBS5 Bardet-Biedl syndrome 5 3.116
TMEM67 transmembrane protein 67 3.099
BBS9 Bardet-Biedl syndrome 9 3.096
BBS12 Bardet-Biedl syndrome 12 3.056
IFT88 intraflagellar transport 88 3.039
CEP290 centrosomal protein 290kDa 3.022
IFT80 intraflagellar transport 80 3.015
MKS1 Meckel syndrome, type 1 3.011
ARL13B ADP-ribosylation factor-like 13B 2.999
CC2D2A coiled-coil and C2 domain containing 2A 2.994
RPGRIP1L RPGRIP1-like 2.993
OFD1 oral-facial-digital syndrome 1 2.978
IFT172 intraflagellar transport 172 2.967
TMEM216 transmembrane protein 216 2.963
TTC21B tetratricopeptide repeat domain 21B 2.95
WDR19 WD repeat domain 19 2.947
WDR35 WD repeat domain 35 2.897
IFT140 intraflagellar transport 140 2.864
GLI1 GLI family zinc finger 1 2.857
CPLANE1 ciliogenesis and planar polarity effector complex subunit 1 2.846
KIAA0586 KIAA0586 2.838
NPHP1 nephronophthisis 1 (juvenile) 2.819
EVC Ellis van Creveld protein 2.808
KIF7 kinesin family member 7 2.803
GLI2 GLI family zinc finger 2 2.794
IFT27 intraflagellar transport 27 2.792
HOXD13 homeobox D13 2.788
PTCH1 patched 1 2.782
KIF3A kinesin family member 3A 2.778
IFT52 intraflagellar transport 52 2.751
TCTN3 tectonic family member 3 2.747
BBIP1 BBSome interacting protein 1 2.743
IFT122 intraflagellar transport 122 2.742
TCTN2 tectonic family member 2 2.742
IFT43 intraflagellar transport 43 2.736
AHI1 Abelson helper integration site 1 2.713
SMO smoothened, frizzled class receptor 2.712
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 2.706
B9D1 B9 protein domain 1 2.687
ZNF141 zinc finger protein 141 2.684
SDCCAG8 serologically defined colon cancer antigen 8 2.668
TTC8 tetratricopeptide repeat domain 8 2.661
WDPCP WD repeat containing planar cell polarity effector 2.656
C2CD3 C2 calcium-dependent domain containing 3 2.646
TMEM231 transmembrane protein 231 2.643
B9D2 B9 protein domain 2 2.641
CEP164 centrosomal protein 164kDa 2.64
IHH indian hedgehog 2.627
IQCE IQ motif containing E 2.623
TCTN1 tectonic family member 1 2.616
IFT74 intraflagellar transport 74 2.616
NEK1 NIMA-related kinase 1 2.598
ALX4 ALX homeobox 4 2.578
NPHP4 nephronophthisis 4 2.568
NPHP3 nephronophthisis 3 (adolescent) 2.558
ALMS1 Alstrom syndrome protein 1 2.556
IFT20 intraflagellar transport 20 2.543
TULP3 tubby like protein 3 2.54
HAND2 heart and neural crest derivatives expressed 2 2.534
INVS inversin 2.498
RAB8A RAB8A, member RAS oncogene family 2.484
CEP120 centrosomal protein 120kDa 2.473
IFT81 intraflagellar transport 81 2.465
SCLT1 sodium channel and clathrin linker 1 2.445
SUFU suppressor of fused homolog (Drosophila) 2.44
CCP110 centriolar coiled coil protein 110kDa 2.43
IFT57 intraflagellar transport 57 2.429
LZTFL1 leucine zipper transcription factor-like 1 2.429
KIAA0825 KIAA0825 2.418
SSTR3 somatostatin receptor 3 2.393
INTU inturned planar cell polarity protein 2.385
TMEM107 transmembrane protein 107 2.377
HOXD12 homeobox D12 2.374
RAB3IP RAB3A interacting protein 2.359
FGF8 fibroblast growth factor 8 (androgen-induced) 2.355
IFT54 intraflagellar transport 54 2.353
TMEM237 transmembrane protein 237 2.347
CNTLN centlein, centrosomal protein 2.327
HYLS1 hydrolethalus syndrome 1 2.324
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 2.309
IQCB1 IQ motif containing B1 2.307
BMP4 bone morphogenetic protein 4 2.306
NEK8 NIMA-related kinase 8 2.282
GPR161 G protein-coupled receptor 161 2.282
BHLHA9 basic helix-loop-helix family, member a9 2.281
PKD2 polycystic kidney disease 2 (autosomal dominant) 2.279
STKLD1 serine/threonine kinase-like domain containing 1 2.279
SOX9 SRY (sex determining region Y)-box 9 2.278
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa 2.277
RPGR retinitis pigmentosa GTPase regulator 2.272
IFT46 intraflagellar transport 46 2.261
HOXD11 homeobox D11 2.243
CEP41 centrosomal protein 41kDa 2.239
DHCR7 7-dehydrocholesterol reductase 2.237
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 2.227
CEP83 centrosomal protein 83kDa 2.222
KIF3B kinesin family member 3B 2.215
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 2.207
RNF32 ring finger protein 32 2.202
MCHR1 melanin-concentrating hormone receptor 1 2.186
CCDC28B coiled-coil domain containing 28B 2.18
PKD1 polycystic kidney disease 1 (autosomal dominant) 2.18
HOXA13 homeobox A13 2.176
KIF17 kinesin family member 17 2.171
PITX1 paired-like homeodomain 1 2.164
NEK9 NIMA-related kinase 9 2.164
FUZ fuzzy planar cell polarity protein 2.152
RAB23 RAB23, member RAS oncogene family 2.15
IFT22 intraflagellar transport 22 2.15
FGF4 fibroblast growth factor 4 2.148
SALL1 spalt-like transcription factor 1 2.137
MSX2 msh homeobox 2 2.124
MSX1 msh homeobox 1 2.117
ARL3 ADP-ribosylation factor-like 3 2.096
PCNT pericentrin 2.095
AKT3 v-akt murine thymoma viral oncogene homolog 3 2.083
TRIM32 tripartite motif containing 32 2.079
CPLANE2 ciliogenesis and planar polarity effector complex subunit 2 2.07
TMEM138 transmembrane protein 138 2.058
CEP19 centrosomal protein 19kDa 2.057
ADCY3 adenylate cyclase 3 2.056
FBF1 Fas (TNFRSF6) binding factor 1 2.053
TBX5 T-box 5 2.052
ARL13A ADP-ribosylation factor-like 13A 2.052
RHO rhodopsin 2.047
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 2.033
TBC1D32 TBC1 domain family, member 32 2.026
IFT38 intraflagellar transport 38 2.024
GREM1 gremlin 1, DAN family BMP antagonist 2.021
CSPP1 centrosome and spindle pole associated protein 1 2.008
PAX6 paired box 6 2.008
MIPOL1 mirror-image polydactyly 1 2.008
TTBK2 tau tubulin kinase 2 2.003
OTX2 orthodenticle homeobox 2 2.003
ARL6 ADP-ribosylation factor-like 6 2.002
ZIC2 Zic family member 2 1.982
CEP97 centrosomal protein 97kDa 1.963
ARMC9 armadillo repeat containing 9 1.956
CCND2 cyclin D2 1.947
SIX3 SIX homeobox 3 1.944
TXNDC15 thioredoxin domain containing 15 1.927
CEP89 centrosomal protein 89kDa 1.925
FGF10 fibroblast growth factor 10 1.924
BMP7 bone morphogenetic protein 7 1.916
GDF5 growth differentiation factor 5 1.911
DDX59 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 1.911
EFCAB7 EF-hand calcium binding domain 7 1.909
KIF24 kinesin family member 24 1.887
NIN ninein (GSK3B interacting protein) 1.886
MEGF8 multiple EGF-like-domains 8 1.886
TBX3 T-box 3 1.87
EPHA4 EPH receptor A4 1.861
PTCH2 patched 2 1.86
TNC tenascin C 1.858
GREM2 gremlin 2, DAN family BMP antagonist 1.858
CHD7 chromodomain helicase DNA binding protein 7 1.855
FGF17 fibroblast growth factor 17 1.852
TULP1 tubby like protein 1 1.838
CTCF CCCTC-binding factor (zinc finger protein) 1.838
COL2A1 collagen, type II, alpha 1 1.83
IRX6 iroquois homeobox 6 1.825
CDON cell adhesion associated, oncogene regulated 1.825
ALX3 ALX homeobox 3 1.825
KIAA0753 KIAA0753 1.824
NKX2-2 NK2 homeobox 2 1.824
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6 1.82
PORCN porcupine homolog (Drosophila) 1.817
FGF9 fibroblast growth factor 9 1.814
TWIST1 twist family bHLH transcription factor 1 1.812
IRX3 iroquois homeobox 3 1.812
ZIC3 Zic family member 3 1.811
FGF18 fibroblast growth factor 18 1.811
WNT6 wingless-type MMTV integration site family, member 6 1.807
FGF3 fibroblast growth factor 3 1.807
CBY1 chibby homolog 1 (Drosophila) 1.805
RAB11A RAB11A, member RAS oncogene family 1.793
FGF20 fibroblast growth factor 20 1.788
MC4R melanocortin 4 receptor 1.788
TMEM17 transmembrane protein 17 1.785
FGF16 fibroblast growth factor 16 1.783
FGFR3 fibroblast growth factor receptor 3 1.78
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.776
NOM1 nucleolar protein with MIF4G domain 1 1.776
NIPBL Nipped-B homolog (Drosophila) 1.775
FGF22 fibroblast growth factor 22 1.775
TOGARAM1 TOG array regulator of axonemal microtubules 1 1.774
FGF5 fibroblast growth factor 5 1.769
RUNX2 runt-related transcription factor 2 1.769
VANGL2 VANGL planar cell polarity protein 2 1.768
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.762
FGF6 fibroblast growth factor 6 1.759
FAM149B1 family with sequence similarity 149, member B1 1.757
DLX5 distal-less homeobox 5 1.756
PAX9 paired box 9 1.756
KIFAP3 kinesin-associated protein 3 1.755
FGFR2 fibroblast growth factor receptor 2 1.752
EHD1 EH-domain containing 1 1.749
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 1.748
CEP104 centrosomal protein 104kDa 1.74
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.739
ACAN aggrecan 1.735
TBX4 T-box 4 1.733
FGF7 fibroblast growth factor 7 1.731
PAX3 paired box 3 1.728
WNT7A wingless-type MMTV integration site family, member 7A 1.726
DHH desert hedgehog 1.722
EFNB1 ephrin-B1 1.722
CROCC ciliary rootlet coiled-coil, rootletin 1.717
HESX1 HESX homeobox 1 1.716
SMAD9 SMAD family member 9 1.715
FGFR1 fibroblast growth factor receptor 1 1.71
DYNLT1 dynein, light chain, Tctex-type 1 1.709
SPATA7 spermatogenesis associated 7 1.708
OCRL oculocerebrorenal syndrome of Lowe 1.705
FOXA2 forkhead box A2 1.704
PCM1 pericentriolar material 1 1.702
TGFB1 transforming growth factor, beta 1 1.702
DVL1 dishevelled segment polarity protein 1 1.691
BMP2 bone morphogenetic protein 2 1.688
USH2A Usher syndrome 2A (autosomal recessive, mild) 1.688
RABL2A RAB, member of RAS oncogene family-like 2A 1.684
ZSWIM6 zinc finger, SWIM-type containing 6 1.676
SALL4 spalt-like transcription factor 4 1.674
RAB28 RAB28, member RAS oncogene family 1.674
ETV5 ets variant 5 1.673
LCA5 Leber congenital amaurosis 5 1.672
PRPH2 peripherin 2 (retinal degeneration, slow) 1.664
PKD1L1 polycystic kidney disease 1 like 1 1.661
PITX2 paired-like homeodomain 2 1.661
HOXD10 homeobox D10 1.653
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.65
ETV4 ets variant 4 1.643
PIBF1 progesterone immunomodulatory binding factor 1 1.642
GLIS2 GLIS family zinc finger 2 1.639
MOSMO modulator of smoothened 1.628
EYS eyes shut homolog (Drosophila) 1.624
RPE65 retinal pigment epithelium-specific protein 65kDa 1.62
SIX6 SIX homeobox 6 1.619
CEP131 centrosomal protein 131kDa 1.61
GAS1 growth arrest-specific 1 1.609
DYNLL1 dynein, light chain, LC8-type 1 1.609
NKX3-2 NK3 homeobox 2 1.605
LEPR leptin receptor 1.604
DISP1 dispatched homolog 1 (Drosophila) 1.6
DLX6 distal-less homeobox 6 1.598
MKKS McKusick-Kaufman syndrome 1.595
PRRX1 paired related homeobox 1 1.595
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 1.592
CEP170 centrosomal protein 170kDa 1.592
TMEM218 transmembrane protein 218 1.588
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 1.588
CEP63 centrosomal protein 63kDa 1.587
FOXJ1 forkhead box J1 1.585
RAB34 RAB34, member RAS oncogene family 1.583
ODF2 outer dense fiber of sperm tails 2 1.58
CDK20 cyclin-dependent kinase 20 1.58
FRAS1 Fraser extracellular matrix complex subunit 1 1.578
NOG noggin 1.578
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.577
ESX1 ESX homeobox 1 1.576
CETN2 centrin, EF-hand protein, 2 1.573
PAX1 paired box 1 1.572
TRIM8 tripartite motif containing 8 1.57
LHX3 LIM homeobox 3 1.569
CFAP410 cilia and flagella associated protein 410 1.56
POMC proopiomelanocortin 1.558
LHX4 LIM homeobox 4 1.553
TBX1 T-box 1 1.553
PAX2 paired box 2 1.551
DACH1 dachshund family transcription factor 1 1.551
CNGB1 cyclic nucleotide gated channel beta 1 1.549
IRX5 iroquois homeobox 5 1.548
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.54
MNX1 motor neuron and pancreas homeobox 1 1.538
TBX2 T-box 2 1.535
GDF6 growth differentiation factor 6 1.533
RABIF RAB interacting factor 1.533
GPC3 glypican 3 1.529
TRIP11 thyroid hormone receptor interactor 11 1.529
NPY2R neuropeptide Y receptor Y2 1.525
RABL2B RAB, member of RAS oncogene family-like 2B 1.523
BMPR1B bone morphogenetic protein receptor, type IB 1.522
TUB tubby bipartite transcription factor 1.521
NDE1 nudE neurodevelopment protein 1 1.521
IRX1 iroquois homeobox 1 1.517
CEP135 centrosomal protein 135kDa 1.516
ZNF423 zinc finger protein 423 1.516
DNAH11 dynein, axonemal, heavy chain 11 1.516
HOXD9 homeobox D9 1.514
TBX6 T-box 6 1.512
LRRC45 leucine rich repeat containing 45 1.51
NKX6-1 NK6 homeobox 1 1.508
SASS6 spindle assembly 6 homolog (C. elegans) 1.508
EMX2 empty spiracles homeobox 2 1.507
EN2 engrailed homeobox 2 1.505
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.502
NKX6-2 NK6 homeobox 2 1.5
WNT5A wingless-type MMTV integration site family, member 5A 1.499
EBP emopamil binding protein (sterol isomerase) 1.498
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.497
INS insulin 1.497
WDR62 WD repeat domain 62 1.493
SOX2 SRY (sex determining region Y)-box 2 1.488
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.484
MYO7A myosin VIIA 1.484
GLB1 galactosidase, beta 1 1.484
FBN2 fibrillin 2 1.483
PRRX2 paired related homeobox 2 1.483
BOC BOC cell adhesion associated, oncogene regulated 1.481
GSK3B glycogen synthase kinase 3 beta 1.481
ARF4 ADP-ribosylation factor 4 1.48
RTTN rotatin 1.477
DNAH5 dynein, axonemal, heavy chain 5 1.474
ACTB actin, beta 1.469
RDH12 retinol dehydrogenase 12 (all-trans/9-cis/11-cis) 1.468
SOX5 SRY (sex determining region Y)-box 5 1.465
BMPR1A bone morphogenetic protein receptor, type IA 1.463
RASA1 RAS p21 protein activator (GTPase activating protein) 1 1.462
DNAI1 dynein, axonemal, intermediate chain 1 1.459
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 1.459
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1.456
SMOC1 SPARC related modular calcium binding 1 1.456
ISL1 ISL LIM homeobox 1 1.451
DYNLL2 dynein, light chain, LC8-type 2 1.448
CYS1 cystin 1 1.448
WNT1 wingless-type MMTV integration site family, member 1 1.447
GPC4 glypican 4 1.446
SHOX short stature homeobox 1.446
GPC5 glypican 5 1.444
RAD21 RAD21 homolog (S. pombe) 1.444
SP7 Sp7 transcription factor 1.443
SMC3 structural maintenance of chromosomes 3 1.439
DVL2 dishevelled segment polarity protein 2 1.438
IGF1 insulin-like growth factor 1 (somatomedin C) 1.435
GPC6 glypican 6 1.435
LEP leptin 1.435
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 1.433
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.431
WNT10B wingless-type MMTV integration site family, member 10B 1.426
EN1 engrailed homeobox 1 1.426
HDAC6 histone deacetylase 6 1.424
FAM161A family with sequence similarity 161, member A 1.423
GATA4 GATA binding protein 4 1.422
ANKMY2 ankyrin repeat and MYND domain containing 2 1.421
CEP350 centrosomal protein 350kDa 1.421
ROM1 retinal outer segment membrane protein 1 1.42
STX3 syntaxin 3 1.42
SCAPER S-phase cyclin A-associated protein in the ER 1.416
PTEN phosphatase and tensin homolog 1.413
EP300 E1A binding protein p300 1.413
POC1A POC1 centriolar protein A 1.411
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 1.407
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.405
FBN1 fibrillin 1 1.405
CRX cone-rod homeobox 1.405
TSC2 tuberous sclerosis 2 1.402
OLIG2 oligodendrocyte lineage transcription factor 2 1.401
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 1.4
H3-3B H3.3 histone B 1.399
PRKD1 protein kinase D1 1.399
H3C13 H3 clustered histone 13 1.398
H3-5 H3.5 histone 1.398
TUBA1A tubulin, alpha 1a 1.398
H3-4 H3.4 histone, cluster member 1.397
HNF1B HNF1 homeobox B 1.397
TTLL6 tubulin tyrosine ligase-like family member 6 1.397
GRK1 G protein-coupled receptor kinase 1 1.397
LMX1B LIM homeobox transcription factor 1, beta 1.395
UNC119B unc-119 homolog B (C. elegans) 1.392
H3C12 H3 clustered histone 12 1.391
FREM1 FRAS1 related extracellular matrix 1 1.39
WNT9B wingless-type MMTV integration site family, member 9B 1.39
FBN3 fibrillin 3 1.387
WNT3A wingless-type MMTV integration site family, member 3A 1.387
PRPF31 pre-mRNA processing factor 31 1.386
FLNA filamin A, alpha 1.386
POC1B POC1 centriolar protein B 1.383
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.383
SMC1A structural maintenance of chromosomes 1A 1.381
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 1.378
DYNLT3 dynein, light chain, Tctex-type 3 1.375
RFX1 regulatory factor X, 1 (influences HLA class II expression) 1.374
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.374
CEP152 centrosomal protein 152kDa 1.374
TTLL10 tubulin tyrosine ligase-like family member 10 1.374
PTF1A pancreas specific transcription factor, 1a 1.372
DYNLRB1 dynein, light chain, roadblock-type 1 1.371
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 1.37
TP63 tumor protein p63 1.37
RAB36 RAB36, member RAS oncogene family 1.369
TAAR1 trace amine associated receptor 1 1.369
SHOX2 short stature homeobox 2 1.368
VPS13B vacuolar protein sorting 13 homolog B (yeast) 1.367
VSX2 visual system homeobox 2 1.366
SOX3 SRY (sex determining region Y)-box 3 1.364
CETN3 centrin, EF-hand protein, 3 1.364
GATA6 GATA binding protein 6 1.363
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.361
RIMS4 regulating synaptic membrane exocytosis 4 1.361
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial 1.36
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.36
FREM2 FRAS1 related extracellular matrix protein 2 1.357
PAX7 paired box 7 1.357
CREBBP CREB binding protein 1.357
CHRD chordin 1.357
EXOC5 exocyst complex component 5 1.355
GNAS GNAS complex locus 1.354
FMN1 formin 1 1.352
SIX1 SIX homeobox 1 1.35
EXOC4 exocyst complex component 4 1.35
PROKR2 prokineticin receptor 2 1.349
IGF2 insulin-like growth factor 2 1.347
PROP1 PROP paired-like homeobox 1 1.346
ALB albumin 1.346
WNT4 wingless-type MMTV integration site family, member 4 1.345
IRF6 interferon regulatory factor 6 1.342
NSD1 nuclear receptor binding SET domain protein 1 1.342
MCIDAS multiciliate differentiation and DNA synthesis associated cell cycle protein 1.341
HHIP hedgehog interacting protein 1.339
FBXW4 F-box and WD repeat domain containing 4 1.331
FBLN1 fibulin 1 1.33
SEPTIN2 septin 2 1.33
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.329
UNC119 unc-119 homolog (C. elegans) 1.328
DEPDC5 DEP domain containing 5 1.328
KATNB1 katanin p80 (WD repeat containing) subunit B 1 1.323
AXIN2 axin 2 1.322
LHX2 LIM homeobox 2 1.322
MMP13 matrix metallopeptidase 13 1.321
TGIF1 TGFB-induced factor homeobox 1 1.318
NODAL nodal growth differentiation factor 1.316
TRAPPC6A trafficking protein particle complex 6A 1.316
CCDC40 coiled-coil domain containing 40 1.315
LEF1 lymphoid enhancer-binding factor 1 1.313
CDHR1 cadherin-related family member 1 1.311
TWIST2 twist family bHLH transcription factor 2 1.311
ZIC1 Zic family member 1 1.31
EPHA7 EPH receptor A7 1.309
MDFIC MyoD family inhibitor domain containing 1.309
SIM1 single-minded family bHLH transcription factor 1 1.306
TP53 tumor protein p53 1.302
HOXA11 homeobox A11 1.301
FGF2 fibroblast growth factor 2 (basic) 1.298
SOX6 SRY (sex determining region Y)-box 6 1.298
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 1.297
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 1.296
FGF13 fibroblast growth factor 13 1.296
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) 1.293
SRY sex determining region Y 1.293
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 1.291
KIF19 kinesin family member 19 1.29
JAG1 jagged 1 1.287
SH2B1 SH2B adaptor protein 1 1.286
DAW1 dynein assembly factor with WDR repeat domains 1 1.286
AGRP agouti related neuropeptide 1.286
ANOS1 anosmin 1 1.286
CEP162 centrosomal protein 162kDa 1.283
CBY3 chibby homolog 3 (Drosophila) 1.282
KIF3C kinesin family member 3C 1.282
MAP3K20 mitogen-activated protein kinase kinase kinase 20 1.279
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 1.277
PCSK1 proprotein convertase subtilisin/kexin type 1 1.276
VANGL1 VANGL planar cell polarity protein 1 1.274
ZBTB18 zinc finger and BTB domain containing 18 1.273
PTHLH parathyroid hormone-like hormone 1.272
PLK4 polo-like kinase 4 1.272
RFX2 regulatory factor X, 2 (influences HLA class II expression) 1.271
GJA1 gap junction protein, alpha 1, 43kDa 1.271
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 1.27
FOXG1 forkhead box G1 1.268
CNTRL centriolin 1.265
FLNB filamin B, beta 1.264
RAB6A RAB6A, member RAS oncogene family 1.264
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 1.262
CHIA chitinase, acidic 1.261
FOXC1 forkhead box C1 1.261
NDNF neuron-derived neurotrophic factor 1.258
CTU2 cytosolic thiouridylase subunit 2 homolog (S. pombe) 1.257
PRH2 proline-rich protein HaeIII subfamily 2 1.257
TBL1X transducin (beta)-like 1X-linked 1.256
CEP250 centrosomal protein 250kDa 1.254
KIF2A kinesin heavy chain member 2A 1.253
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 1.253
CEP78 centrosomal protein 78kDa 1.253
RFX3 regulatory factor X, 3 (influences HLA class II expression) 1.253
FOXF1 forkhead box F1 1.252
SPRY4 sprouty homolog 4 (Drosophila) 1.25
COL9A1 collagen, type IX, alpha 1 1.249
EOMES eomesodermin 1.249
KISS1R KISS1 receptor 1.247
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 1.247
LRP5 low density lipoprotein receptor-related protein 5 1.246
USH1C Usher syndrome 1C (autosomal recessive, severe) 1.243
MED12 mediator complex subunit 12 1.241
ANKUB1 ankyrin repeat and ubiquitin domain containing 1 1.238
NINL ninein-like 1.236
TTLL3 tubulin tyrosine ligase-like family member 3 1.234
KMT2D lysine (K)-specific methyltransferase 2D 1.23
USP9X ubiquitin specific peptidase 9, X-linked 1.23
FTO fat mass and obesity associated 1.23
SNAP29 synaptosomal-associated protein, 29kDa 1.226
CEP128 centrosomal protein 128kDa 1.226
DPCD deleted in primary ciliary dyskinesia homolog (mouse) 1.224
EXOC6 exocyst complex component 6 1.224
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit 1.224
FSHB follicle stimulating hormone, beta polypeptide 1.223
DUSP6 dual specificity phosphatase 6 1.222
POU3F4 POU class 3 homeobox 4 1.221
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 1.221
DZANK1 double zinc ribbon and ankyrin repeat domains 1 1.219
CNGA3 cyclic nucleotide gated channel alpha 3 1.217
VAX1 ventral anterior homeobox 1 1.215
ARRB2 arrestin, beta 2 1.213
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.212
HYDIN HYDIN, axonemal central pair apparatus protein 1.211
INPP5B inositol polyphosphate-5-phosphatase, 75kDa 1.21
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 1.209
HOXB8 homeobox B8 1.208
LRP6 low density lipoprotein receptor-related protein 6 1.208
CCDC14 coiled-coil domain containing 14 1.207
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 1.207
SIX2 SIX homeobox 2 1.206
SMAD6 SMAD family member 6 1.206
FAT4 FAT atypical cadherin 4 1.205
KIF27 kinesin family member 27 1.204
COL10A1 collagen, type X, alpha 1 1.204
ACVR1 activin A receptor, type I 1.204
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 1.202
ZFPM2 zinc finger protein, FOG family member 2 1.201
RAI1 retinoic acid induced 1 1.201
NEK2 NIMA-related kinase 2 1.2
SCARF2 scavenger receptor class F, member 2 1.2
EHMT1 euchromatic histone-lysine N-methyltransferase 1 1.197
ANKRD11 ankyrin repeat domain 11 1.196
DNAI2 dynein, axonemal, intermediate chain 2 1.196
PCARE photoreceptor cilium actin regulator 1.195
DLX2 distal-less homeobox 2 1.192
WNT9A wingless-type MMTV integration site family, member 9A 1.191
TTLL5 tubulin tyrosine ligase-like family member 5 1.188
COL1A1 collagen, type I, alpha 1 1.187
DZIP1L DAZ interacting zinc finger protein 1-like 1.185
SAG S-antigen; retina and pineal gland (arrestin) 1.184
ESYT2 extended synaptotagmin-like protein 2 1.184
MAGEL2 melanoma antigen family L2 1.184
DYNLRB2 dynein, light chain, roadblock-type 2 1.182
TCOF1 Treacher Collins-Franceschetti syndrome 1 1.182
RNF157 ring finger protein 157 1.181
RABEP1 rabaptin, RAB GTPase binding effector protein 1 1.178
CETN1 centrin, EF-hand protein, 1 1.178
LHX1 LIM homeobox 1 1.178
GATA1 GATA binding protein 1 (globin transcription factor 1) 1.177
RBM33 RNA binding motif protein 33 1.175
GLIS1 GLIS family zinc finger 1 1.169
WHRN whirlin 1.168
HOXA2 homeobox A2 1.166
CFC1 cripto, FRL-1, cryptic family 1 1.166
TRPV4 transient receptor potential cation channel, subfamily V, member 4 1.164
BGLAP bone gamma-carboxyglutamate (gla) protein 1.163
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 1.162
PTH parathyroid hormone 1.16
DNAH8 dynein, axonemal, heavy chain 8 1.16
LBR lamin B receptor 1.16
TRAPPC2 trafficking protein particle complex 2 1.159
ADCY6 adenylate cyclase 6 1.159
HHAT hedgehog acyltransferase 1.159
DPH2 DPH2 homolog (S. cerevisiae) 1.159
HOXA10 homeobox A10 1.159
DVL3 dishevelled segment polarity protein 3 1.158
MAPKBP1 mitogen-activated protein kinase binding protein 1 1.156
GBX2 gastrulation brain homeobox 2 1.155
EXT1 exostosin glycosyltransferase 1 1.155
RHOA ras homolog family member A 1.154
MYOD1 myogenic differentiation 1 1.153
RNF216 ring finger protein 216 1.152
ARRB1 arrestin, beta 1 1.151
KIF21A kinesin family member 21A 1.15
FMR1 fragile X mental retardation 1 1.15
TMEM80 transmembrane protein 80 1.149
PKD2L1 polycystic kidney disease 2-like 1 1.149
COL1A2 collagen, type I, alpha 2 1.148
PXDN peroxidasin 1.147
AFP alpha-fetoprotein 1.147
ETV2 ets variant 2 1.145
GP1BB glycoprotein Ib (platelet), beta polypeptide 1.144
DAND5 DAN domain family member 5, BMP antagonist 1.143
RAB17 RAB17, member RAS oncogene family 1.142
OSR2 odd-skipped related transciption factor 2 1.141
TUBD1 tubulin, delta 1 1.141
DACT1 dishevelled-binding antagonist of beta-catenin 1 1.14
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 1.139
BMP5 bone morphogenetic protein 5 1.139
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase 1.139
ZBTB16 zinc finger and BTB domain containing 16 1.137
CEP192 centrosomal protein 192kDa 1.137
SPAG6 sperm associated antigen 6 1.136
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 1.134
ATXN10 ataxin 10 1.133
FANCB Fanconi anemia, complementation group B 1.133
TSEN54 TSEN54 tRNA splicing endonuclease subunit 1.133
NSDHL NAD(P) dependent steroid dehydrogenase-like 1.131
EPHB3 EPH receptor B3 1.131
SOS1 son of sevenless homolog 1 (Drosophila) 1.13
NPY5R neuropeptide Y receptor Y5 1.13
KAT6B K(lysine) acetyltransferase 6B 1.129
DCTN1 dynactin 1 1.129
AXIN1 axin 1 1.129
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase 1.129
RP1L1 retinitis pigmentosa 1-like 1 1.128
HOXA9 homeobox A9 1.128
STK36 serine/threonine kinase 36 1.127
DPH1 diphthamide biosynthesis 1 1.127
SLC26A2 solute carrier family 26 (anion exchanger), member 2 1.127
UBE3B ubiquitin protein ligase E3B 1.127
NR2E3 nuclear receptor subfamily 2, group E, member 3 1.127
EYA1 EYA transcriptional coactivator and phosphatase 1 1.125
NEK11 NIMA-related kinase 11 1.124
NPY neuropeptide Y 1.123
KIF14 kinesin family member 14 1.123
PXDNL peroxidasin-like 1.122
RARG retinoic acid receptor, gamma 1.122
PLEK2 pleckstrin 2 1.121
CUX1 cut-like homeobox 1 1.12
RARB retinoic acid receptor, beta 1.119
WNT3 wingless-type MMTV integration site family, member 3 1.119
DLL1 delta-like 1 (Drosophila) 1.118
KCTD17 potassium channel tetramerization domain containing 17 1.117
MAP2K1 mitogen-activated protein kinase kinase 1 1.117
CDH23 cadherin-related 23 1.116
FEZF1 FEZ family zinc finger 1 1.113
CFAP53 cilia and flagella associated protein 53 1.113
PLEK pleckstrin 1.112
WT1 Wilms tumor 1 1.11
CDKN3 cyclin-dependent kinase inhibitor 3 1.11
TUBB3 tubulin, beta 3 class III 1.109
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20 1.109
LEFTY2 left-right determination factor 2 1.108
NDN necdin, melanoma antigen (MAGE) family member 1.105
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 1.105
RP9 retinitis pigmentosa 9 (autosomal dominant) 1.103
NDEL1 nudE neurodevelopment protein 1-like 1 1.102
POC5 POC5 centriolar protein 1.101
LGALS4 lectin, galactoside-binding, soluble, 4 1.1
ANKRD6 ankyrin repeat domain 6 1.099
LMBRD2 LMBR1 domain containing 2 1.097
PCDH15 protocadherin-related 15 1.095
POU5F1 POU class 5 homeobox 1 1.095
PHGDH phosphoglycerate dehydrogenase 1.094
NR0B1 nuclear receptor subfamily 0, group B, member 1 1.094
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 1.094
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 1.093
SLCO6A1 solute carrier organic anion transporter family, member 6A1 1.093
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 1.092
HOXB6 homeobox B6 1.09
CUL3 cullin 3 1.087
NEK4 NIMA-related kinase 4 1.087
MYH14 myosin, heavy chain 14, non-muscle 1.087
HDAC9 histone deacetylase 9 1.086
NR5A1 nuclear receptor subfamily 5, group A, member 1 1.085
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor 1.082
NF1 neurofibromin 1 1.082
ADCY8 adenylate cyclase 8 (brain) 1.08
TXLNB taxilin beta 1.08
PEX6 peroxisomal biogenesis factor 6 1.079
GOLGA2 golgin A2 1.079
MAPK3 mitogen-activated protein kinase 3 1.079
TRAPPC3 trafficking protein particle complex 3 1.078
KCTD13 potassium channel tetramerization domain containing 13 1.078
EGF epidermal growth factor 1.077
STIL SCL/TAL1 interrupting locus 1.077
GPR22 G protein-coupled receptor 22 1.074
SAP18 Sin3A-associated protein, 18kDa 1.072
NANOG Nanog homeobox 1.072
BARX1 BARX homeobox 1 1.07
CCDC39 coiled-coil domain containing 39 1.07
AVPR2 arginine vasopressin receptor 2 1.069
L1CAM L1 cell adhesion molecule 1.069
GPR63 G protein-coupled receptor 63 1.069
HAND1 heart and neural crest derivatives expressed 1 1.068
EFTUD2 elongation factor Tu GTP binding domain containing 2 1.067
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.066
HNF4A hepatocyte nuclear factor 4, alpha 1.066
ARR3 arrestin 3, retinal (X-arrestin) 1.066
MEF2C myocyte enhancer factor 2C 1.065
DSPP dentin sialophosphoprotein 1.064
ZBTB11 zinc finger and BTB domain containing 11 1.062
KLLN killin, p53-regulated DNA replication inhibitor 1.062
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 1.061
CALML6 calmodulin-like 6 1.061
POLR1D polymerase (RNA) I polypeptide D, 16kDa 1.058
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 1.058
SEC63 SEC63 homolog (S. cerevisiae) 1.058
TLX1 T-cell leukemia homeobox 1 1.057
LRP2 low density lipoprotein receptor-related protein 2 1.057
VPS25 vacuolar protein sorting 25 homolog (S. cerevisiae) 1.057
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 1.056
FBXW11 F-box and WD repeat domain containing 11 1.056
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 1.054
RCC1 regulator of chromosome condensation 1 1.054
CCNQ cyclin Q 1.053
CHSY1 chondroitin sulfate synthase 1 1.053
PRICKLE2 prickle homolog 2 (Drosophila) 1.053
EFNB2 ephrin-B2 1.052
MYO5A myosin VA (heavy chain 12, myoxin) 1.05
MAK male germ cell-associated kinase 1.05
TGFB3 transforming growth factor, beta 3 1.05
TRNP1 TMF1-regulated nuclear protein 1 1.049
CALML4 calmodulin-like 4 1.048
LDB1 LIM domain binding 1 1.048
WAPL WAPL cohesin release factor 1.047
RFX4 regulatory factor X, 4 (influences HLA class II expression) 1.046
CALML3 calmodulin-like 3 1.046
ACVR2B activin A receptor, type IIB 1.045
CALML5 calmodulin-like 5 1.045
PRICKLE1 prickle homolog 1 (Drosophila) 1.045
CCNO cyclin O 1.045
ZPR1 ZPR1 zinc finger 1.043
MECP2 methyl CpG binding protein 2 1.043
LBX1 ladybird homeobox 1 1.042
SPRY2 sprouty homolog 2 (Drosophila) 1.042
SST somatostatin 1.041
ASCL1 achaete-scute family bHLH transcription factor 1 1.04
SHOC2 soc-2 suppressor of clear homolog (C. elegans) 1.039
TUBE1 tubulin, epsilon 1 1.038
DBX2 developing brain homeobox 2 1.038
TMEM11 transmembrane protein 11 1.037
TBX18 T-box 18 1.037
ARHGAP6 Rho GTPase activating protein 6 1.036
PAPPA pregnancy-associated plasma protein A, pappalysin 1 1.035
MBD5 methyl-CpG binding domain protein 5 1.035
NKX2-5 NK2 homeobox 5 1.034
CRELD1 cysteine-rich with EGF-like domains 1 1.034
TUBB2B tubulin, beta 2B class IIb 1.033
EMX1 empty spiracles homeobox 1 1.031
GAS8 growth arrest-specific 8 1.031
DISC1 disrupted in schizophrenia 1 1.031
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 1.03
PRKCSH protein kinase C substrate 80K-H 1.028
SETD5 SET domain containing 5 1.027
EXOC3 exocyst complex component 3 1.027
CDK5RAP2 CDK5 regulatory subunit associated protein 2 1.027
SMAD4 SMAD family member 4 1.026
CNGA1 cyclic nucleotide gated channel alpha 1 1.026
MOK MOK protein kinase 1.026
NOTCH1 notch 1 1.026
RILPL1 Rab interacting lysosomal protein-like 1 1.025
PPP2R5D protein phosphatase 2, regulatory subunit B', delta 1.024
ZNF335 zinc finger protein 335 1.024
TRPS1 trichorhinophalangeal syndrome I 1.024
SNURF SNRPN upstream reading frame 1.024
GREB1L growth regulation by estrogen in breast cancer-like 1.024
DCDC2 doublecortin domain containing 2 1.023
RIMS1 regulating synaptic membrane exocytosis 1 1.021
GOLPH3 golgi phosphoprotein 3 (coat-protein) 1.02
BICD2 bicaudal D homolog 2 (Drosophila) 1.019
MSMO1 methylsterol monooxygenase 1 1.019
WDR73 WD repeat domain 73 1.017
FAM234B family with sequence similarity 234 member B 1.017
SLCO2A1 solute carrier organic anion transporter family, member 2A1 1.016
EPHA1 EPH receptor A1 1.016
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 1.016
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.016
CEP55 centrosomal protein 55kDa 1.016
LZTR1 leucine-zipper-like transcription regulator 1 1.015
STRA6 stimulated by retinoic acid 6 1.014
FOXC2 forkhead box C2 1.014
CEP57 centrosomal protein 57kDa 1.013
CDH17 cadherin 17, LI cadherin (liver-intestine) 1.013
ZNF699 zinc finger protein 699 1.012
CNGB3 cyclic nucleotide gated channel beta 3 1.012
SYNE2 spectrin repeat containing, nuclear envelope 2 1.012
SNRPN small nuclear ribonucleoprotein polypeptide N 1.012
FRA10AC1 fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1 1.012
GOLGB1 golgin B1 1.011
ZNF629 zinc finger protein 629 1.01
ADGRV1 adhesion G protein-coupled receptor V1 1.01
ZNF501 zinc finger protein 501 1.01
ZNF44 zinc finger protein 44 1.009
ZNF763 zinc finger protein 763 1.008
ZNF436 zinc finger protein 436 1.008
AURKA aurora kinase A 1.008
CCND1 cyclin D1 1.008
KIFC3 kinesin family member C3 1.008
TSEN34 TSEN34 tRNA splicing endonuclease subunit 1.007
HCCS holocytochrome c synthase 1.007
SOX10 SRY (sex determining region Y)-box 10 1.007
DZIP1 DAZ interacting zinc finger protein 1 1.007
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.006
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.006
TNPO1 transportin 1 1.003
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 1.0
ZNF569 zinc finger protein 569 1.0
MID1 midline 1 1.0
TRARG1 trafficking regulator of GLUT4 (SLC2A4) 1 1.0