Polymyositis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0085655
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Genes

174 genes associated with the disease Polymyositis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACR acrosin
ACTN3 actinin, alpha 3 (gene/pseudogene)
ADAM17 ADAM metallopeptidase domain 17
ADAM19 ADAM metallopeptidase domain 19
AGER advanced glycosylation end product-specific receptor
AGO2 argonaute RISC catalytic component 2
AIRE autoimmune regulator
ALOX5 arachidonate 5-lipoxygenase
BEST1 bestrophin 1
BLK BLK proto-oncogene, Src family tyrosine kinase
CABIN1 calcineurin binding protein 1
CALD1 caldesmon 1
CAMP cathelicidin antimicrobial peptide
CCL17 chemokine (C-C motif) ligand 17
CCL19 chemokine (C-C motif) ligand 19
CCL2 chemokine (C-C motif) ligand 2
CCL21 chemokine (C-C motif) ligand 21
CCL22 chemokine (C-C motif) ligand 22
CCN1 cellular communication network factor 1
CCN2 cellular communication network factor 2
CCR7 chemokine (C-C motif) receptor 7
CD163 CD163 molecule
CD207 CD207 molecule, langerin
CD28 CD28 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD68 CD68 molecule
CD80 CD80 molecule
CD86 CD86 molecule
CDK2AP2 cyclin-dependent kinase 2 associated protein 2
CDKN2A cyclin-dependent kinase inhibitor 2A
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHIT1 chitinase 1 (chitotriosidase)
CKLF chemokine-like factor
CLCN1 chloride channel, voltage-sensitive 1
CLEC4C C-type lectin domain family 4, member C
CNTN2 contactin 2 (axonal)
CPM carboxypeptidase M
CRP C-reactive protein, pentraxin-related
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR4 chemokine (C-X-C motif) receptor 4
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DCPS decapping enzyme, scavenger
DCTN4 dynactin 4 (p62)
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEFB103A defensin, beta 103A
DEFB103B defensin, beta 103B
DMD dystrophin
DNASE1L3 deoxyribonuclease I-like 3
DYSF dysferlin
ELANE elastase, neutrophil expressed
ERBB3 erb-b2 receptor tyrosine kinase 3
EXOSC10 exosome component 10
EXOSC9 exosome component 9
FABP3 fatty acid binding protein 3, muscle and heart
FAM167A family with sequence similarity 167, member A
FOXP3 forkhead box P3
FSCN1 fascin actin-bundling protein 1
FSD1 fibronectin type III and SPRY domain containing 1
FSD1L fibronectin type III and SPRY domain containing 1-like
GLIS3 GLIS family zinc finger 3
GNLY granulysin
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
HARS1 histidyl-tRNA synthetase 1
HARS2 histidyl-tRNA synthetase 2, mitochondrial
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGB1 high mobility group box 1
HPGDS hematopoietic prostaglandin D synthase
IFIH1 interferon induced with helicase C domain 1
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IL15 interleukin 15
IL15RA interleukin 15 receptor, alpha
IL17A interleukin 17A
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL2 interleukin 2
IL21 interleukin 21
IL21R interleukin 21 receptor
IL22 interleukin 22
IL2RA interleukin 2 receptor, alpha
IL3RA interleukin 3 receptor, alpha (low affinity)
IL4 interleukin 4
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
IRF5 interferon regulatory factor 5
ISG20 interferon stimulated exonuclease gene 20kDa
ISYNA1 inositol-3-phosphate synthase 1
KARS1 lysyl-tRNA synthetase 1
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
MB myoglobin
MEFV Mediterranean fever
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIP major intrinsic protein of lens fiber
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MYD88 myeloid differentiation primary response 88
MYH2 myosin, heavy chain 2, skeletal muscle, adult
NECAP2 NECAP endocytosis associated 2
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NLRP3 NLR family, pyrin domain containing 3
NOS2 nitric oxide synthase 2, inducible
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NT5C1A 5'-nucleotidase, cytosolic IA
NUP62 nucleoporin 62kDa
OPTN optineurin
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
POMC proopiomelanocortin
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRC protein tyrosine phosphatase, receptor type, C
PUF60 poly-U binding splicing factor 60KDa
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RBM45 RNA binding motif protein 45
RIT2 Ras-like without CAAX 2
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPP14 ribonuclease P/MRP 14kDa subunit
S100A11 S100 calcium binding protein A11
S100A9 S100 calcium binding protein A9
S100B S100 calcium binding protein B
SCN4A sodium channel, voltage gated, type IV alpha subunit
SDC1 syndecan 1
SF3B6 splicing factor 3b, subunit 6, 14kDa
SLURP1 secreted LY6/PLAUR domain containing 1
SMAD2 SMAD family member 2
SMN1 survival of motor neuron 1, telomeric
SMN2 survival of motor neuron 2, centromeric
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNRPN small nuclear ribonucleoprotein polypeptide N
SNURF SNRPN upstream reading frame
SOCS3 suppressor of cytokine signaling 3
SOD1 superoxide dismutase 1, soluble
SQSTM1 sequestosome 1
STMN1 stathmin 1
SUB1 SUB1 homolog (S. cerevisiae)
TARDBP TAR DNA binding protein
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TGM2 transglutaminase 2
TIA1 TIA1 cytotoxic granule-associated RNA binding protein
TIMP1 TIMP metallopeptidase inhibitor 1
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR7 toll-like receptor 7
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TP53 tumor protein p53
TRIM33 tripartite motif containing 33
TYK2 tyrosine kinase 2
UTRN utrophin
VEGFA vascular endothelial growth factor A