Ponatinib Gene Set

Dataset DrugBank Drug Targets
Category physical interactions
Type drug
Description A benzamide obtained by the formal condensation of the carboxy group of 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic acid with the anilino group of 4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)aniline. (Chemical Entities of Biological Interest Ontology, CHEBI_78543)
External Link http://www.drugbank.ca/drugs/DB08901
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Genes

17 interacting proteins for the Ponatinib drug from the curated DrugBank Drug Targets dataset.

Symbol Name
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
BCR breakpoint cluster region
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FGFR4 fibroblast growth factor receptor 4
FLT3 fms-related tyrosine kinase 3
KDR kinase insert domain receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LCK LCK proto-oncogene, Src family tyrosine kinase
LYN LYN proto-oncogene, Src family tyrosine kinase
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
RET ret proto-oncogene
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TEK TEK tyrosine kinase, endothelial