| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ponatinib perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ponatinib_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.294879 |
| GPC5 | glypican 5 | 0.0871609 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0756039 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0651405 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0523156 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0490712 |
| COL3A1 | collagen, type III, alpha 1 | 0.04567 |
| PRKD1 | protein kinase D1 | 0.035481 |
| CENPF | centromere protein F, 350/400kDa | 0.0347939 |
| MKI67 | marker of proliferation Ki-67 | 0.0346558 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.034553 |
| SEPTIN9 | septin 9 | 0.0340981 |
| PLAT | plasminogen activator, tissue | 0.0331359 |
| LMNA | lamin A/C | 0.0331142 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0329604 |
| CLTC | clathrin, heavy chain (Hc) | 0.0327361 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0309684 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.030869 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0300098 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0300025 |
| DST | dystonin | 0.0298683 |
| LDHA | lactate dehydrogenase A | 0.0297431 |
| ATXN1 | ataxin 1 | 0.0270106 |
| GOLGA4 | golgin A4 | 0.0261048 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0260265 |
| ARRDC3 | arrestin domain containing 3 | 0.0257005 |
| TNRC6A | trinucleotide repeat containing 6A | 0.025592 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0255432 |
| CCDC59 | coiled-coil domain containing 59 | 0.0254241 |
| PHF3 | PHD finger protein 3 | 0.0251157 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0250186 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0245859 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0242539 |
| CHRM3 | cholinergic receptor, muscarinic 3 | 0.0242285 |
| FAM13A | family with sequence similarity 13, member A | 0.0236716 |
| PLEC | plectin | 0.0235736 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0232227 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0226109 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0217974 |
| MTREX | Mtr4 exosome RNA helicase | 0.0217727 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0217694 |
| TET1 | tet methylcytosine dioxygenase 1 | 0.0216744 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.0216568 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0215907 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0215771 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0215191 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0214496 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0213577 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0210237 |
| CALU | calumenin | 0.0207753 |
| TOM1L2 | target of myb1-like 2 (chicken) | 0.0207054 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.0206239 |
| RFX7 | regulatory factor X, 7 | 0.0206088 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0205785 |
| FLNB | filamin B, beta | 0.0205003 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0204569 |
| TPR | translocated promoter region, nuclear basket protein | 0.0202994 |
| STC2 | stanniocalcin 2 | 0.0202314 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 0.0198889 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0194617 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 0.0194453 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0194003 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0192867 |
| YTHDC1 | YTH domain containing 1 | 0.019132 |
| C1ORF21 | chromosome 1 open reading frame 21 | 0.0189705 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0189216 |
| HMBOX1 | homeobox containing 1 | 0.0189206 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0189027 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.018733 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0185232 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0185154 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.01846 |
| KLF6 | Kruppel-like factor 6 | 0.0184301 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.0183807 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.0183758 |
| RB1 | retinoblastoma 1 | 0.0183013 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 0.0182925 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0182749 |
| STAC | SH3 and cysteine rich domain | 0.0182571 |
| YEATS2 | YEATS domain containing 2 | 0.0181289 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0180327 |
| FDXR | ferredoxin reductase | 0.0179438 |
| TNRC6B | trinucleotide repeat containing 6B | 0.017887 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.0177984 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.01763 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0175269 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.0174568 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0174191 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | 0.017375 |
| PCMTD1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | 0.0173727 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0173208 |
| MAP4 | microtubule-associated protein 4 | 0.0172621 |
| NFX1 | nuclear transcription factor, X-box binding 1 | 0.0172025 |
| ZNF33B | zinc finger protein 33B | 0.0171291 |
| PRKCA | protein kinase C, alpha | 0.0170367 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0170114 |
| ANXA2 | annexin A2 | 0.0170013 |
| SYT1 | synaptotagmin I | 0.016817 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0167749 |
| CPSF6 | cleavage and polyadenylation specific factor 6, 68kDa | 0.0167465 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.37319 |
| LSAMP | limbic system-associated membrane protein | -0.195551 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.141602 |
| NRG1 | neuregulin 1 | -0.131671 |
| RPS6 | ribosomal protein S6 | -0.108708 |
| VIM | vimentin | -0.090522 |
| PTMA | prothymosin, alpha | -0.0872732 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0784713 |
| FMN1 | formin 1 | -0.0722218 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0702708 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.067684 |
| RNF213 | ring finger protein 213 | -0.0664232 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0659401 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0641819 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0619945 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0619911 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0595482 |
| KLHL13 | kelch-like family member 13 | -0.0593481 |
| RPLP1 | ribosomal protein, large, P1 | -0.0582181 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0564321 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0550714 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0545471 |
| RPS24 | ribosomal protein S24 | -0.0532774 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0524189 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0524169 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0511545 |
| ASPH | aspartate beta-hydroxylase | -0.0510747 |
| FHIT | fragile histidine triad | -0.0509164 |
| RIGI | RNA sensor RIG-I | -0.0497945 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0497302 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0495978 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0484335 |
| SP100 | SP100 nuclear antigen | -0.0458492 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0449058 |
| IER3 | immediate early response 3 | -0.0439227 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0435616 |
| RPS19 | ribosomal protein S19 | -0.0415761 |
| B2M | beta-2-microglobulin | -0.0409477 |
| GNAS | GNAS complex locus | -0.0408966 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0407448 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0406955 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0406932 |
| FTL | ferritin, light polypeptide | -0.0405405 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0403677 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0403042 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0402558 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0397347 |
| MX2 | MX dynamin-like GTPase 2 | -0.039227 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0383769 |
| RPL32 | ribosomal protein L32 | -0.0382668 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0380601 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0379003 |
| VCL | vinculin | -0.0371817 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0371579 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0369332 |
| RPL34 | ribosomal protein L34 | -0.0366709 |
| RBM39 | RNA binding motif protein 39 | -0.0357034 |
| QKI | QKI, KH domain containing, RNA binding | -0.0342033 |
| CCNL1 | cyclin L1 | -0.0340328 |
| RPL35A | ribosomal protein L35a | -0.0339574 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0339283 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0337401 |
| DGKH | diacylglycerol kinase, eta | -0.0337261 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0336629 |
| RAD51B | RAD51 paralog B | -0.033451 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0332759 |
| RPS16 | ribosomal protein S16 | -0.0328083 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0319321 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0318548 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0315392 |
| DACH2 | dachshund family transcription factor 2 | -0.031526 |
| RPS3 | ribosomal protein S3 | -0.0313931 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0313556 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0313089 |
| ZNF804A | zinc finger protein 804A | -0.0309371 |
| NREP | neuronal regeneration related protein | -0.0304761 |
| TMSB10 | thymosin beta 10 | -0.0303267 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0298706 |
| RPS12 | ribosomal protein S12 | -0.0298581 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0298226 |
| CNTN4 | contactin 4 | -0.0297188 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0295456 |
| RPS25 | ribosomal protein S25 | -0.0294794 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0288905 |
| RPS5 | ribosomal protein S5 | -0.0284328 |
| COPA | coatomer protein complex, subunit alpha | -0.0283162 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0282351 |
| RNF145 | ring finger protein 145 | -0.0280967 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0280449 |
| MX1 | MX dynamin-like GTPase 1 | -0.0275004 |
| RPL26 | ribosomal protein L26 | -0.0272016 |
| TOP1 | topoisomerase (DNA) I | -0.0272007 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0268435 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0267757 |
| PLPP1 | phospholipid phosphatase 1 | -0.0263595 |
| RPLP0 | ribosomal protein, large, P0 | -0.0263173 |
| AUTS2 | autism susceptibility candidate 2 | -0.026297 |
| RGS5 | regulator of G-protein signaling 5 | -0.0261276 |
| H3-3B | H3.3 histone B | -0.0258466 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0257936 |
