Portal Hypertension Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0020541
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Genes

166 genes associated with the disease Portal Hypertension in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
ACVRL1 activin A receptor type II-like 1
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRB3 adrenoceptor beta 3
AFP alpha-fetoprotein
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
ALB albumin
ALMS1 Alstrom syndrome protein 1
ALOX5 arachidonate 5-lipoxygenase
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
ANKRD11 ankyrin repeat domain 11
ANO1 anoctamin 1, calcium activated chloride channel
ARHGAP31 Rho GTPase activating protein 31
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARRB2 arrestin, beta 2
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
AVP arginine vasopressin
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like
BDKRB2 bradykinin receptor B2
BOC BOC cell adhesion associated, oncogene regulated
BTNL2 butyrophilin-like 2
CA9 carbonic anhydrase IX
CALR calreticulin
CC2D2A coiled-coil and C2 domain containing 2A
CCN2 cellular communication network factor 2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLDN1 claudin 1
CPEB1 cytoplasmic polyadenylation element binding protein 1
CPEB4 cytoplasmic polyadenylation element binding protein 4
CST3 cystatin C
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CX3CL1 chemokine (C-X3-C motif) ligand 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DCDC2 doublecortin domain containing 2
DDAH1 dimethylarginine dimethylaminohydrolase 1
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DGUOK deoxyguanosine kinase
DLL4 delta-like 4 (Drosophila)
DOCK6 dedicator of cytokinesis 6
DUSP1 dual specificity phosphatase 1
EDN1 endothelin 1
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
ENG endoglin
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
F5 coagulation factor V (proaccelerin, labile factor)
FARSB phenylalanyl-tRNA synthetase, beta subunit
FBL fibrillarin
GBE1 glucan (1,4-alpha-), branching enzyme 1
GDF2 growth differentiation factor 2
GLIS3 GLIS family zinc finger 3
GPBAR1 G protein-coupled bile acid receptor 1
GPR35 G protein-coupled receptor 35
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GRK2 G protein-coupled receptor kinase 2
HFE hemochromatosis
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMOX1 heme oxygenase 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA4 heat shock 70kDa protein 4
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IL12A interleukin 12A
IL12RB1 interleukin 12 receptor, beta 1
IL17A interleukin 17A
IL18 interleukin 18
IL1B interleukin 1, beta
IL6 interleukin 6
IMPACT impact RWD domain protein
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IRF5 interferon regulatory factor 5
ISYNA1 inositol-3-phosphate synthase 1
ITCH itchy E3 ubiquitin protein ligase
JAK2 Janus kinase 2
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KDR kinase insert domain receptor
KLF2 Kruppel-like factor 2
KLK3 kallikrein-related peptidase 3
LCN2 lipocalin 2
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS9 lectin, galactoside-binding, soluble, 9
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MAT2B methionine adenosyltransferase II, beta
MEOX2 mesenchyme homeobox 2
MMEL1 membrane metallo-endopeptidase-like 1
MPL MPL proto-oncogene, thrombopoietin receptor
MST1 macrophage stimulating 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NAAA N-acylethanolamine acid amidase
NANOS1 nanos homolog 1 (Drosophila)
NANOS3 nanos homolog 3 (Drosophila)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NEUROG3 neurogenin 3
NGFR nerve growth factor receptor
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NR1D1 nuclear receptor subfamily 1, group D, member 1
NR1H4 nuclear receptor subfamily 1, group H, member 4
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
PCDH20 protocadherin 20
PCNA proliferating cell nuclear antigen
PDE5A phosphodiesterase 5A, cGMP-specific
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PGF placental growth factor
PIGM phosphatidylinositol glycan anchor biosynthesis, class M
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PNPLA3 patatin-like phospholipase domain containing 3
POU2AF1 POU class 2 associating factor 1
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PRL prolactin
PTEN phosphatase and tensin homolog
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBP4 retinol binding protein 4, plasma
RBPJ recombination signal binding protein for immunoglobulin kappa J region
REN renin
RETN resistin
RHOA ras homolog family member A
RPGRIP1L RPGRIP1-like
RSC1A1 regulatory solute carrier protein, family 1, member 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SH2B2 SH2B adaptor protein 2
SHPK sedoheptulokinase
SLC30A10 solute carrier family 30, member 10
SMAD4 SMAD family member 4
SMIM1 small integral membrane protein 1 (Vel blood group)
SP110 SP110 nuclear body protein
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SPP1 secreted phosphoprotein 1
SST somatostatin
TCF4 transcription factor 4
TET2 tet methylcytosine dioxygenase 2
TGFB1 transforming growth factor, beta 1
TH tyrosine hydroxylase
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TJP2 tight junction protein 2
TLX2 T-cell leukemia homeobox 2
TM7SF2 transmembrane 7 superfamily member 2
TMEM67 transmembrane protein 67
TNF tumor necrosis factor
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNPO3 transportin 3
TXNRD3 thioredoxin reductase 3
UTS2 urotensin 2
UTS2B urotensin 2B
UTS2R urotensin 2 receptor
VASH1 vasohibin 1
VEGFA vascular endothelial growth factor A
VWF von Willebrand factor
XDH xanthine dehydrogenase
XPR1 xenotropic and polytropic retrovirus receptor 1
ZNF469 zinc finger protein 469