| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Posaconazole perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Posaconazole_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.177506 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.173874 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.16672 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.134955 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0889655 |
| DST | dystonin | 0.0877997 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0825079 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0734695 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0669353 |
| FBN1 | fibrillin 1 | 0.0656202 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0639573 |
| LOXL2 | lysyl oxidase-like 2 | 0.0598271 |
| GPC6 | glypican 6 | 0.0586406 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0583524 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0579807 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0561436 |
| FLNB | filamin B, beta | 0.0550398 |
| CD109 | CD109 molecule | 0.0541095 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0539198 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0535494 |
| MYOF | myoferlin | 0.0525814 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0513612 |
| B2M | beta-2-microglobulin | 0.0510681 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0506405 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0483024 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0480316 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0474191 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.047386 |
| RUNX1 | runt-related transcription factor 1 | 0.0471793 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0469567 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0462331 |
| OGA | O-GlcNAcase | 0.0461699 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0450929 |
| ZNF292 | zinc finger protein 292 | 0.0450437 |
| CD44 | CD44 molecule (Indian blood group) | 0.0448012 |
| NAV2 | neuron navigator 2 | 0.0447248 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0445877 |
| ATP13A3 | ATPase type 13A3 | 0.0440807 |
| THBS2 | thrombospondin 2 | 0.0436281 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0435137 |
| HDAC9 | histone deacetylase 9 | 0.0424495 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0424346 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 0.0418073 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0408871 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0408655 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0407739 |
| SFTPA2 | surfactant protein A2 | 0.0407631 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0405863 |
| PRELID2 | PRELI domain containing 2 | 0.0402912 |
| FRMD5 | FERM domain containing 5 | 0.0399169 |
| ACTN4 | actinin, alpha 4 | 0.0387084 |
| FNIP1 | folliculin interacting protein 1 | 0.0383853 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0382948 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0368764 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0366605 |
| MB21D2 | Mab-21 domain containing 2 | 0.0366376 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0364986 |
| FADS2 | fatty acid desaturase 2 | 0.036037 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0359908 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0357668 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0350373 |
| COL1A2 | collagen, type I, alpha 2 | 0.0346061 |
| GOLGA4 | golgin A4 | 0.0343975 |
| XPO1 | exportin 1 | 0.0343663 |
| SQSTM1 | sequestosome 1 | 0.0341006 |
| MSI2 | musashi RNA-binding protein 2 | 0.0334066 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0332942 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.033263 |
| RTN4 | reticulon 4 | 0.0330478 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0329109 |
| YEATS2 | YEATS domain containing 2 | 0.0324137 |
| ANK2 | ankyrin 2, neuronal | 0.0323859 |
| NBAS | neuroblastoma amplified sequence | 0.0321979 |
| HELZ | helicase with zinc finger | 0.0321071 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0320708 |
| CTSB | cathepsin B | 0.0317623 |
| SBF2 | SET binding factor 2 | 0.0314855 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0314679 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0310506 |
| AUTS2 | autism susceptibility candidate 2 | 0.0304923 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0302977 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0302619 |
| TMOD1 | tropomodulin 1 | 0.030067 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0298843 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0298821 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 0.0296921 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0296352 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0293405 |
| ATXN1 | ataxin 1 | 0.0292179 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0290979 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.0284888 |
| GASK1B | golgi associated kinase 1B | 0.0284723 |
| RNF145 | ring finger protein 145 | 0.0283638 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0281792 |
| SPAG9 | sperm associated antigen 9 | 0.0280425 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0280081 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0276818 |
| FAM13A | family with sequence similarity 13, member A | 0.0276793 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 0.027664 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0273327 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.213963 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.177634 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.170129 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.139249 |
| CDH13 | cadherin 13 | -0.128471 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.100289 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0878 |
| TMSB10 | thymosin beta 10 | -0.0793722 |
| MT2A | metallothionein 2A | -0.0716891 |
| AHNAK | AHNAK nucleoprotein | -0.0697086 |
| CCND1 | cyclin D1 | -0.0685592 |
| PTMA | prothymosin, alpha | -0.0612837 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.060495 |
| COL5A1 | collagen, type V, alpha 1 | -0.0602911 |
| PODXL | podocalyxin-like | -0.0590433 |
| LMNA | lamin A/C | -0.0583411 |
| EGFR | epidermal growth factor receptor | -0.0580631 |
| EFNA5 | ephrin-A5 | -0.054735 |
| S100A6 | S100 calcium binding protein A6 | -0.0497975 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0484027 |
| ACTG1 | actin gamma 1 | -0.045482 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0453258 |
| POTEF | POTE ankyrin domain family, member F | -0.0374985 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0353184 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0325208 |
| CAVIN1 | caveolae associated protein 1 | -0.0318951 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0308156 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0294121 |
| FRMD4A | FERM domain containing 4A | -0.0292085 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0288918 |
| TPM4 | tropomyosin 4 | -0.0286826 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0281552 |
| CYTH3 | cytohesin 3 | -0.0277378 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0275808 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0274701 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0265198 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0262161 |
| RPL37A | ribosomal protein L37a | -0.025461 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0247972 |
| CANX | calnexin | -0.0245765 |
| FN1 | fibronectin 1 | -0.0243016 |
| RPS6 | ribosomal protein S6 | -0.0233305 |
| RPL12 | ribosomal protein L12 | -0.0227501 |
| TMSB4X | thymosin beta 4, X-linked | -0.0220525 |
| INTS6 | integrator complex subunit 6 | -0.021823 |
| S100A10 | S100 calcium binding protein A10 | -0.0217609 |
| RPS8 | ribosomal protein S8 | -0.0214574 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0213357 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0209055 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0208703 |
| KIAA1549L | KIAA1549-like | -0.0207746 |
| FSTL1 | follistatin-like 1 | -0.0206377 |
| RPS3 | ribosomal protein S3 | -0.020453 |
| RPLP1 | ribosomal protein, large, P1 | -0.0202503 |
| RIGI | RNA sensor RIG-I | -0.0201029 |
| RPL35A | ribosomal protein L35a | -0.0200994 |
| MAP1B | microtubule-associated protein 1B | -0.020013 |
| RPL26 | ribosomal protein L26 | -0.0198186 |
| MYADM | myeloid-associated differentiation marker | -0.0196195 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0195374 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0191811 |
| TBCA | tubulin folding cofactor A | -0.0189856 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0189163 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0187028 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0182675 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0179789 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0176749 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0174847 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0174287 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0173849 |
| CUX1 | cut-like homeobox 1 | -0.0172491 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0172051 |
| CDK6 | cyclin-dependent kinase 6 | -0.017145 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0169444 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0168991 |
| RACK1 | receptor for activated C kinase 1 | -0.0168518 |
| ACER3 | alkaline ceramidase 3 | -0.0168292 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0167099 |
| RPLP2 | ribosomal protein, large, P2 | -0.0166329 |
| RPL34 | ribosomal protein L34 | -0.0162787 |
| CEP112 | centrosomal protein 112kDa | -0.0162666 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0158979 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0158082 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0157643 |
| PRSS23 | protease, serine, 23 | -0.0157462 |
| RPS24 | ribosomal protein S24 | -0.0157192 |
| RPL28 | ribosomal protein L28 | -0.0157031 |
| RASAL2 | RAS protein activator like 2 | -0.0155446 |
| RPS27A | ribosomal protein S27a | -0.0155102 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit | -0.015489 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0154368 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0154306 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0154291 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0154108 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0153189 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0152488 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0152244 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0151457 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0148621 |
| C12ORF75 | chromosome 12 open reading frame 75 | -0.0147638 |
