| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Posaconazole perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Posaconazole_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TENM3 | teneurin transmembrane protein 3 | 0.0756358 |
| PCBP2 | poly(rC) binding protein 2 | 0.0755658 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0739582 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0739489 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0669694 |
| DST | dystonin | 0.0635613 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0583683 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0570034 |
| MED13L | mediator complex subunit 13-like | 0.0563722 |
| CCNL1 | cyclin L1 | 0.0548657 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.05386 |
| USP34 | ubiquitin specific peptidase 34 | 0.052658 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0521287 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0506435 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0501439 |
| RPL23 | ribosomal protein L23 | 0.0470726 |
| EPHA6 | EPH receptor A6 | 0.0466942 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0460428 |
| AXIN2 | axin 2 | 0.0457901 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0454579 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0443039 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0427675 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0412587 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0399519 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0397074 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0394919 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0394294 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0390852 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0381593 |
| CPOX | coproporphyrinogen oxidase | 0.037386 |
| NEK7 | NIMA-related kinase 7 | 0.0368327 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.036325 |
| NBAS | neuroblastoma amplified sequence | 0.0362747 |
| TBK1 | TANK-binding kinase 1 | 0.0359648 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0356884 |
| GASK1B | golgi associated kinase 1B | 0.0348071 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0347481 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0347156 |
| TMSB10 | thymosin beta 10 | 0.0341608 |
| CDK19 | cyclin-dependent kinase 19 | 0.0339089 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0338506 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0331364 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0325232 |
| KLHL24 | kelch-like family member 24 | 0.0319769 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0319105 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | 0.0314943 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.031434 |
| ARRDC3 | arrestin domain containing 3 | 0.0314027 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0312684 |
| SMYD3 | SET and MYND domain containing 3 | 0.0311385 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0309236 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0304145 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0303298 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0300276 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0299501 |
| HDAC9 | histone deacetylase 9 | 0.0298706 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0298646 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0296769 |
| PRR16 | proline rich 16 | 0.0296763 |
| YEATS2 | YEATS domain containing 2 | 0.0296742 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0294116 |
| PGK1 | phosphoglycerate kinase 1 | 0.029371 |
| RAD51B | RAD51 paralog B | 0.0288294 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0284834 |
| XPO1 | exportin 1 | 0.028456 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0281698 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0281672 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.028044 |
| TFG | TRK-fused gene | 0.0279812 |
| ZNF292 | zinc finger protein 292 | 0.027941 |
| TPM3 | tropomyosin 3 | 0.0279294 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0279262 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0276822 |
| MGAT4C | MGAT4 family, member C | 0.0275748 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0273979 |
| CEP192 | centrosomal protein 192kDa | 0.027322 |
| CEP70 | centrosomal protein 70kDa | 0.026963 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.02696 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0266912 |
| RPL3 | ribosomal protein L3 | 0.0264584 |
| SYT1 | synaptotagmin I | 0.0264145 |
| MSI2 | musashi RNA-binding protein 2 | 0.0262759 |
| ANXA1 | annexin A1 | 0.0262496 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0262388 |
| TNPO1 | transportin 1 | 0.0260162 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0259543 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0259234 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0255175 |
| LPIN2 | lipin 2 | 0.0254901 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0252437 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0252342 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0251009 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0250518 |
| PCNX1 | pecanex 1 | 0.0250201 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0250075 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0250042 |
| DNAJC13 | DnaJ (Hsp40) homolog, subfamily C, member 13 | 0.0249609 |
| OGA | O-GlcNAcase | 0.0248873 |
| FRYL | FRY-like | 0.024805 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0247614 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.236514 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.2058 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.148514 |
| ACTG1 | actin gamma 1 | -0.112874 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0861605 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0829726 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0810037 |
| HMGA2 | high mobility group AT-hook 2 | -0.0792279 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0769807 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0719307 |
| PCDH7 | protocadherin 7 | -0.0635043 |
| EHBP1 | EH domain binding protein 1 | -0.0630137 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0602439 |
| ZNF804A | zinc finger protein 804A | -0.0566327 |
| PTMA | prothymosin, alpha | -0.0562219 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0550162 |
| RASAL2 | RAS protein activator like 2 | -0.0546989 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0500561 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.044984 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0427953 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0412641 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0404779 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0398231 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.036978 |
| CLDN1 | claudin 1 | -0.0362174 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0360927 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0353434 |
| ASPH | aspartate beta-hydroxylase | -0.0350791 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0346081 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0340638 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0314156 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0305197 |
| NAV3 | neuron navigator 3 | -0.0304575 |
| CCND1 | cyclin D1 | -0.0299924 |
| TUBA1B | tubulin, alpha 1b | -0.0299907 |
| S100A6 | S100 calcium binding protein A6 | -0.0287669 |
| MKI67 | marker of proliferation Ki-67 | -0.0284627 |
| JMJD1C | jumonji domain containing 1C | -0.0284176 |
| NHSL1 | NHS-like 1 | -0.0282376 |
| BCHE | butyrylcholinesterase | -0.0273559 |
| EDN1 | endothelin 1 | -0.0268653 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0268459 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0266451 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | -0.0257468 |
| AHNAK | AHNAK nucleoprotein | -0.0257041 |
| RTN4 | reticulon 4 | -0.0254922 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0248626 |
| CEP112 | centrosomal protein 112kDa | -0.0248207 |
| MTAP | methylthioadenosine phosphorylase | -0.0248061 |
| TMEM41B | transmembrane protein 41B | -0.0247965 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.024433 |
| CANX | calnexin | -0.0241894 |
| NLGN1 | neuroligin 1 | -0.0239716 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | -0.0237367 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0235959 |
| GNAS | GNAS complex locus | -0.0235531 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0235237 |
| NABP1 | nucleic acid binding protein 1 | -0.0226635 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0225362 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0219915 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0219368 |
| MYPN | myopalladin | -0.0212561 |
| BRI3BP | BRI3 binding protein | -0.0207331 |
| HMGB1 | high mobility group box 1 | -0.0206768 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.020662 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0202957 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0201879 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0201781 |
| S100A10 | S100 calcium binding protein A10 | -0.0201063 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0199779 |
| CAVIN1 | caveolae associated protein 1 | -0.0198244 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0192862 |
| RPS27A | ribosomal protein S27a | -0.019193 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0190797 |
| KLF6 | Kruppel-like factor 6 | -0.0189358 |
| CMIP | c-Maf inducing protein | -0.0189236 |
| CUX1 | cut-like homeobox 1 | -0.0189191 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.0187656 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0187499 |
| TPM4 | tropomyosin 4 | -0.0187202 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.018704 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0183478 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0181796 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0180304 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0179071 |
| LMO7 | LIM domain 7 | -0.0177749 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.017759 |
| RPS24 | ribosomal protein S24 | -0.0176644 |
| BPTF | bromodomain PHD finger transcription factor | -0.0173363 |
| GCG | glucagon | -0.0172593 |
| RPS6 | ribosomal protein S6 | -0.0170127 |
| EGR1 | early growth response 1 | -0.016921 |
| R3HDM2 | R3H domain containing 2 | -0.0168573 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | -0.0167663 |
| RPL38 | ribosomal protein L38 | -0.0167171 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0166561 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0164708 |
| TBCA | tubulin folding cofactor A | -0.0164027 |
| BRCA1 | breast cancer 1, early onset | -0.0163236 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0162131 |
