| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Posaconazole perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Posaconazole_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.187418 |
| NDRG1 | N-myc downstream regulated 1 | 0.145906 |
| FAM13A | family with sequence similarity 13, member A | 0.141932 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.133019 |
| ANXA2 | annexin A2 | 0.121082 |
| ITGA6 | integrin, alpha 6 | 0.111624 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.102075 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0987297 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0968233 |
| TXNIP | thioredoxin interacting protein | 0.0920327 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0889436 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0879003 |
| FAT1 | FAT atypical cadherin 1 | 0.0867217 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0865219 |
| PRELID2 | PRELI domain containing 2 | 0.0819915 |
| LDHA | lactate dehydrogenase A | 0.080434 |
| TNS4 | tensin 4 | 0.0798848 |
| RNF43 | ring finger protein 43 | 0.079721 |
| DSPP | dentin sialophosphoprotein | 0.0761684 |
| PGK1 | phosphoglycerate kinase 1 | 0.0734326 |
| INSIG1 | insulin induced gene 1 | 0.0733094 |
| ENO1 | enolase 1, (alpha) | 0.0729867 |
| FLNB | filamin B, beta | 0.0726934 |
| CCNY | cyclin Y | 0.0718942 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0707936 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0703886 |
| EZR | ezrin | 0.0694687 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0677374 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0662682 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0659385 |
| EREG | epiregulin | 0.0657312 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0654555 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0648962 |
| TRIM2 | tripartite motif containing 2 | 0.0647469 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0632791 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0627328 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0617018 |
| ANXA11 | annexin A11 | 0.0600956 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0594384 |
| FDPS | farnesyl diphosphate synthase | 0.0592307 |
| PRSS3 | protease, serine, 3 | 0.0587651 |
| H1-0 | H1.0 linker histone | 0.0571775 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0562643 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0555403 |
| ACTN4 | actinin, alpha 4 | 0.0552141 |
| KRT8 | keratin 8, type II | 0.0551387 |
| EHF | ets homologous factor | 0.0534794 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0532309 |
| GPHN | gephyrin | 0.0531696 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0528505 |
| MED13L | mediator complex subunit 13-like | 0.0527986 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | 0.0509844 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0497551 |
| RREB1 | ras responsive element binding protein 1 | 0.048905 |
| PCDHB16 | protocadherin beta 16 | 0.0486222 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0486094 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0485823 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0481156 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0480207 |
| SHROOM3 | shroom family member 3 | 0.0476208 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0467009 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0461686 |
| PIGR | polymeric immunoglobulin receptor | 0.0460581 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0453189 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0452121 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0452005 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0449447 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.044652 |
| EPCAM | epithelial cell adhesion molecule | 0.0442556 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0440456 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.0425976 |
| KRT18 | keratin 18, type I | 0.0425307 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.042513 |
| ABHD2 | abhydrolase domain containing 2 | 0.0424302 |
| CALR | calreticulin | 0.0423159 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0422793 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0421031 |
| ZNF292 | zinc finger protein 292 | 0.0416663 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0409964 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0407907 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.039881 |
| WDR45B | WD repeat domain 45B | 0.0398759 |
| ABHD17C | abhydrolase domain containing 17C | 0.0397862 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0396133 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0393599 |
| TPD52 | tumor protein D52 | 0.0393315 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0388601 |
| RBM39 | RNA binding motif protein 39 | 0.0385051 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.038269 |
| TMEM41B | transmembrane protein 41B | 0.0381195 |
| LMO7 | LIM domain 7 | 0.0380481 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0377496 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0372054 |
| ADD3 | adducin 3 (gamma) | 0.0368005 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0365902 |
| LDLR | low density lipoprotein receptor | 0.0364483 |
| CDC42SE2 | CDC42 small effector 2 | 0.0363288 |
| FNBP1L | formin binding protein 1-like | 0.0362705 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0362089 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.035903 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.12802 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0969257 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.092742 |
| MYO1E | myosin IE | -0.0725459 |
| ACTG1 | actin gamma 1 | -0.0715479 |
| RPS6 | ribosomal protein S6 | -0.0542667 |
| TMSB10 | thymosin beta 10 | -0.0507663 |
| RPS8 | ribosomal protein S8 | -0.048189 |
| NPSR1 | neuropeptide S receptor 1 | -0.0452938 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.042998 |
| EGFR | epidermal growth factor receptor | -0.0392872 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0367492 |
| RPLP2 | ribosomal protein, large, P2 | -0.034943 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0325544 |
| RPL9 | ribosomal protein L9 | -0.032542 |
| VCL | vinculin | -0.0318723 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0317941 |
| RPL35A | ribosomal protein L35a | -0.0314099 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0312119 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0298643 |
| POTEF | POTE ankyrin domain family, member F | -0.0281671 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0278762 |
| TFF1 | trefoil factor 1 | -0.027174 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0266955 |
| RPS29 | ribosomal protein S29 | -0.0266619 |
| CCND1 | cyclin D1 | -0.0265515 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0262153 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0247919 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0235316 |
| CDK13 | cyclin-dependent kinase 13 | -0.0229929 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0229195 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0227687 |
| IER3 | immediate early response 3 | -0.022579 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0225461 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0224111 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0220997 |
| INTS6 | integrator complex subunit 6 | -0.0217502 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0213368 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0207642 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0207269 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0206411 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0201953 |
| RPL37A | ribosomal protein L37a | -0.0201568 |
| POF1B | premature ovarian failure, 1B | -0.0200984 |
| SVIL | supervillin | -0.0197268 |
| RPL31 | ribosomal protein L31 | -0.0195918 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0193637 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0190738 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0190207 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0189378 |
| DEK | DEK proto-oncogene | -0.0187579 |
| CCDC91 | coiled-coil domain containing 91 | -0.018652 |
| TBCA | tubulin folding cofactor A | -0.0185169 |
| HMGB1 | high mobility group box 1 | -0.0184421 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0184302 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0183466 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0183319 |
| MT2A | metallothionein 2A | -0.0182735 |
| VCAN | versican | -0.0182132 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0181811 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0180847 |
| SIK3 | SIK family kinase 3 | -0.0179298 |
| S100A6 | S100 calcium binding protein A6 | -0.0178093 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.017632 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0176259 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0175457 |
| RPS27A | ribosomal protein S27a | -0.0175416 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0171861 |
| AHI1 | Abelson helper integration site 1 | -0.0171167 |
| LAMA4 | laminin, alpha 4 | -0.0170722 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0170644 |
| RPLP1 | ribosomal protein, large, P1 | -0.0170306 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.0170084 |
| RPS19 | ribosomal protein S19 | -0.0168076 |
| HMGA2 | high mobility group AT-hook 2 | -0.016775 |
| AEBP2 | AE binding protein 2 | -0.0164733 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0164618 |
| RPL28 | ribosomal protein L28 | -0.0164263 |
| TUBA1B | tubulin, alpha 1b | -0.0163814 |
| KLK10 | kallikrein-related peptidase 10 | -0.0163511 |
| RPL8 | ribosomal protein L8 | -0.0162355 |
| RPS21 | ribosomal protein S21 | -0.0161893 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0161623 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0158714 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0158618 |
| DSTN | destrin (actin depolymerizing factor) | -0.0157891 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0156012 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0155671 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0155358 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0154912 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0154655 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0154409 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0152754 |
| HEATR5A | HEAT repeat containing 5A | -0.0152572 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0151449 |
| FBXO11 | F-box protein 11 | -0.0150792 |
| COG5 | component of oligomeric golgi complex 5 | -0.0150507 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0150472 |
| CUX1 | cut-like homeobox 1 | -0.0147971 |
| RPL38 | ribosomal protein L38 | -0.0147471 |
