| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Posaconazole perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Posaconazole_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.209496 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.129788 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.118942 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0959237 |
| CAPRIN2 | caprin family member 2 | 0.0816941 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0769563 |
| ENO1 | enolase 1, (alpha) | 0.0767045 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0660935 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0659008 |
| PGK1 | phosphoglycerate kinase 1 | 0.0631646 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0601095 |
| FLNB | filamin B, beta | 0.0592939 |
| FMNL2 | formin-like 2 | 0.0591987 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0589674 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0588308 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0587051 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0583226 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0573863 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0569994 |
| FNIP1 | folliculin interacting protein 1 | 0.0563419 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0539921 |
| EZR | ezrin | 0.0538067 |
| OGA | O-GlcNAcase | 0.0534829 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0528019 |
| RPS12 | ribosomal protein S12 | 0.0525936 |
| SPAG9 | sperm associated antigen 9 | 0.0524347 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0494939 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0489015 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0483086 |
| LDHA | lactate dehydrogenase A | 0.0482698 |
| PCBP2 | poly(rC) binding protein 2 | 0.0481209 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0477984 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0474303 |
| TMSB10 | thymosin beta 10 | 0.0467859 |
| NDRG1 | N-myc downstream regulated 1 | 0.0467772 |
| SQSTM1 | sequestosome 1 | 0.0458792 |
| XPO1 | exportin 1 | 0.0456482 |
| YEATS2 | YEATS domain containing 2 | 0.0454828 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0449198 |
| ZNF292 | zinc finger protein 292 | 0.0447709 |
| PRELID2 | PRELI domain containing 2 | 0.0441735 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0435102 |
| TXNIP | thioredoxin interacting protein | 0.0432988 |
| TSC22D1 | TSC22 domain family, member 1 | 0.043161 |
| RPL23 | ribosomal protein L23 | 0.0418342 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0407551 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0407384 |
| RPS3 | ribosomal protein S3 | 0.0402548 |
| MKI67 | marker of proliferation Ki-67 | 0.0395978 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.038358 |
| RPS19 | ribosomal protein S19 | 0.0382955 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0376019 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.037584 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0373769 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0370902 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0367999 |
| RAD51B | RAD51 paralog B | 0.0365152 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0364206 |
| TOP1 | topoisomerase (DNA) I | 0.0363847 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0360938 |
| PHF21A | PHD finger protein 21A | 0.0360845 |
| ANK2 | ankyrin 2, neuronal | 0.0354177 |
| ARRDC3 | arrestin domain containing 3 | 0.0354105 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0351116 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0350989 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0350261 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0347763 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0342409 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0341431 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0340306 |
| CDK19 | cyclin-dependent kinase 19 | 0.0337633 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0336214 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0333622 |
| SRPK2 | SRSF protein kinase 2 | 0.0332293 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0330269 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0329102 |
| MYO10 | myosin X | 0.0323889 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0322945 |
| APP | amyloid beta (A4) precursor protein | 0.0322094 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.032207 |
| ERBIN | erbb2 interacting protein | 0.0321597 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0321467 |
| CENPF | centromere protein F, 350/400kDa | 0.0321142 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.030793 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0307155 |
| EFNA5 | ephrin-A5 | 0.0306532 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.030584 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0305246 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0304503 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0304436 |
| RTTN | rotatin | 0.0302859 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0302805 |
| CCNL1 | cyclin L1 | 0.0301866 |
| NBAS | neuroblastoma amplified sequence | 0.0301397 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0300641 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0300622 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0298059 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0296704 |
| CEP170 | centrosomal protein 170kDa | 0.0294562 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0292023 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.359661 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.16693 |
| VIM | vimentin | -0.110682 |
| TP63 | tumor protein p63 | -0.0859312 |
| MT2A | metallothionein 2A | -0.0823938 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0779111 |
| ACTG1 | actin gamma 1 | -0.0755976 |
| TXNRD1 | thioredoxin reductase 1 | -0.0712166 |
| TMSB4X | thymosin beta 4, X-linked | -0.0696176 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0693203 |
| CD44 | CD44 molecule (Indian blood group) | -0.0685915 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0606557 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0558784 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0481427 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0435054 |
| RPL36A | ribosomal protein L36a | -0.0427487 |
| HLA-B | major histocompatibility complex, class I, B | -0.0417235 |
| MT1X | metallothionein 1X | -0.0399147 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0355015 |
| RPS24 | ribosomal protein S24 | -0.0354195 |
| SRGN | serglycin | -0.0345928 |
| POTEF | POTE ankyrin domain family, member F | -0.034562 |
| NEK10 | NIMA-related kinase 10 | -0.0312269 |
| RPS6 | ribosomal protein S6 | -0.0312228 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0304674 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0302831 |
| PYGL | phosphorylase, glycogen, liver | -0.030275 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0297369 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0295892 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0287666 |
| SP100 | SP100 nuclear antigen | -0.0287357 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0280354 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0278665 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0272985 |
| RPL28 | ribosomal protein L28 | -0.0272072 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0270059 |
| RIGI | RNA sensor RIG-I | -0.0269266 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0267502 |
| EMP1 | epithelial membrane protein 1 | -0.0263831 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0259485 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0258857 |
| PLSCR1 | phospholipid scramblase 1 | -0.0257701 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0250216 |
| RPL38 | ribosomal protein L38 | -0.0247513 |
| AHNAK | AHNAK nucleoprotein | -0.0246791 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0246209 |
| RASA2 | RAS p21 protein activator 2 | -0.0245666 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0245325 |
| RPS15 | ribosomal protein S15 | -0.0243531 |
| RPS23 | ribosomal protein S23 | -0.0243033 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.024087 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0236572 |
| PDE10A | phosphodiesterase 10A | -0.0232782 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.023173 |
| CMIP | c-Maf inducing protein | -0.0226711 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0222714 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0221087 |
| FERMT1 | fermitin family member 1 | -0.0220119 |
| S100A10 | S100 calcium binding protein A10 | -0.021839 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0217327 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0214777 |
| TGM2 | transglutaminase 2 | -0.0214701 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0212796 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | -0.0212593 |
| OSMR | oncostatin M receptor | -0.0212427 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.020921 |
| PTMA | prothymosin, alpha | -0.0207256 |
| RGS4 | regulator of G-protein signaling 4 | -0.020595 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0204875 |
| MT1E | metallothionein 1E | -0.0200436 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.01982 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.019782 |
| PRDX1 | peroxiredoxin 1 | -0.0196932 |
| RPL7A | ribosomal protein L7a | -0.0195919 |
| RPL32 | ribosomal protein L32 | -0.0194795 |
| SDC4 | syndecan 4 | -0.0193553 |
| RPS16 | ribosomal protein S16 | -0.0193314 |
| RPS29 | ribosomal protein S29 | -0.0192773 |
| ERCC1 | excision repair cross-complementation group 1 | -0.0192436 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0189102 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0187138 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0185869 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0183502 |
| PMP22 | peripheral myelin protein 22 | -0.0182374 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0181597 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0181531 |
| RPS28 | ribosomal protein S28 | -0.0180883 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0178044 |
| ECE1 | endothelin converting enzyme 1 | -0.0177504 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0177204 |
| RGS5 | regulator of G-protein signaling 5 | -0.0176253 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0176233 |
| CCNI | cyclin I | -0.0176097 |
| S100A6 | S100 calcium binding protein A6 | -0.0176039 |
| MB21D2 | Mab-21 domain containing 2 | -0.0175153 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0174615 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0174162 |
| RPLP0 | ribosomal protein, large, P0 | -0.0172233 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0167689 |
| HMGB1 | high mobility group box 1 | -0.016592 |
