| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Posaconazole perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Posaconazole_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.148217 |
| FAM13A | family with sequence similarity 13, member A | 0.123069 |
| NDRG1 | N-myc downstream regulated 1 | 0.110386 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.108667 |
| FNDC3B | fibronectin type III domain containing 3B | 0.107781 |
| LMO7 | LIM domain 7 | 0.103488 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.09233 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0890765 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0876923 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0868997 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0856386 |
| MCL1 | myeloid cell leukemia 1 | 0.0804988 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.078027 |
| ARRDC3 | arrestin domain containing 3 | 0.0746546 |
| ASPH | aspartate beta-hydroxylase | 0.0740104 |
| MYOF | myoferlin | 0.0735271 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0716985 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0693941 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0657643 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0650971 |
| SPAG9 | sperm associated antigen 9 | 0.0650676 |
| TPD52 | tumor protein D52 | 0.0631999 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0629642 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.061851 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0607192 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0598682 |
| LDHA | lactate dehydrogenase A | 0.0594246 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0582853 |
| PDE8A | phosphodiesterase 8A | 0.0576551 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0572304 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0567098 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0566265 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0555601 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0548698 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0547415 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0543848 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0536187 |
| SLTM | SAFB-like, transcription modulator | 0.0528536 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0525664 |
| PCBP2 | poly(rC) binding protein 2 | 0.0519688 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0517877 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0512191 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0504328 |
| SMAD3 | SMAD family member 3 | 0.0500457 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0498963 |
| RNF145 | ring finger protein 145 | 0.0481635 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0480061 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.047951 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.047704 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0475638 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0474793 |
| CCNL1 | cyclin L1 | 0.0469483 |
| ANXA2 | annexin A2 | 0.046129 |
| FDPS | farnesyl diphosphate synthase | 0.0456676 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0455529 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0453413 |
| TXNRD1 | thioredoxin reductase 1 | 0.0447158 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0441234 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0440508 |
| RUNX1 | runt-related transcription factor 1 | 0.043625 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0434182 |
| RAB6A | RAB6A, member RAS oncogene family | 0.042816 |
| HELZ | helicase with zinc finger | 0.0427819 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0423002 |
| CPE | carboxypeptidase E | 0.0418615 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0417292 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0414781 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0411613 |
| UVRAG | UV radiation resistance associated | 0.0411128 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0409402 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0403893 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0400852 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0400043 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0387347 |
| ENO1 | enolase 1, (alpha) | 0.0379938 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0373594 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0372926 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0369947 |
| SLMAP | sarcolemma associated protein | 0.0369498 |
| JMJD1C | jumonji domain containing 1C | 0.0369325 |
| TMEM165 | transmembrane protein 165 | 0.0369233 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0367775 |
| ATP13A3 | ATPase type 13A3 | 0.0367124 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0364564 |
| ANKRD37 | ankyrin repeat domain 37 | 0.0362812 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0358057 |
| PTMA | prothymosin, alpha | 0.0354642 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0354357 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0353797 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0353603 |
| MGAT4C | MGAT4 family, member C | 0.0349122 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0347572 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0347206 |
| TOP1 | topoisomerase (DNA) I | 0.0343423 |
| SCEL | sciellin | 0.0340157 |
| S100A10 | S100 calcium binding protein A10 | 0.0331383 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0331284 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0323243 |
| NCKAP1 | NCK-associated protein 1 | 0.0321654 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0321574 |
| Symbol | Name | Standardized Value |
|---|---|---|
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0521993 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0427797 |
| OSMR | oncostatin M receptor | -0.0383838 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0345486 |
| GM2A | GM2 ganglioside activator | -0.0301064 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0300255 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0294064 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0291303 |
| HLA-B | major histocompatibility complex, class I, B | -0.0282134 |
| CANX | calnexin | -0.0281405 |
| HDLBP | high density lipoprotein binding protein | -0.0272531 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | -0.0258509 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0251666 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0251395 |
| TBC1D22A | TBC1 domain family, member 22A | -0.024318 |
| AHNAK | AHNAK nucleoprotein | -0.0239832 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.023455 |
| SP100 | SP100 nuclear antigen | -0.0231064 |
| RPS24 | ribosomal protein S24 | -0.0230932 |
| RNF213 | ring finger protein 213 | -0.0217796 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0209248 |
| TRIM56 | tripartite motif containing 56 | -0.0203137 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0201793 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0199118 |
| SDC4 | syndecan 4 | -0.0197016 |
| PMP22 | peripheral myelin protein 22 | -0.0195982 |
| FAAH2 | fatty acid amide hydrolase 2 | -0.0193231 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0186961 |
| HM13 | histocompatibility (minor) 13 | -0.0179887 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0178847 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0178228 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0177955 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0176184 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0174496 |
| RIGI | RNA sensor RIG-I | -0.0170953 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0168349 |
| ADAR | adenosine deaminase, RNA-specific | -0.0167539 |
| SEC24D | SEC24 family member D | -0.0167012 |
| AGR2 | anterior gradient 2 | -0.0166647 |
| FAM110C | family with sequence similarity 110, member C | -0.0166119 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.016431 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0157185 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0156752 |
| SMIM14 | small integral membrane protein 14 | -0.0156035 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0155895 |
| STC1 | stanniocalcin 1 | -0.0155182 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0152896 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0152419 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0150918 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0148031 |
| RNF169 | ring finger protein 169 | -0.0147851 |
| PRELID2 | PRELI domain containing 2 | -0.0146909 |
| ALG11 | ALG11, alpha-1,2-mannosyltransferase | -0.0146093 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0145924 |
| FRMD4B | FERM domain containing 4B | -0.0143679 |
| PRKCE | protein kinase C, epsilon | -0.0143555 |
| PLSCR1 | phospholipid scramblase 1 | -0.0143362 |
| SMYD3 | SET and MYND domain containing 3 | -0.0142817 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0142443 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0141949 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0141808 |
| CDK12 | cyclin-dependent kinase 12 | -0.013489 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0134521 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0134036 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0133966 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa | -0.0126496 |
| KIAA1328 | KIAA1328 | -0.0125088 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0123935 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0123541 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0122643 |
| CHMP1B | charged multivesicular body protein 1B | -0.0122406 |
| SLF2 | SMC5-SMC6 complex localization factor 2 | -0.0121774 |
| RPL38 | ribosomal protein L38 | -0.0121445 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0121094 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0118987 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0117548 |
| ABLIM1 | actin binding LIM protein 1 | -0.0117457 |
| GOLGA3 | golgin A3 | -0.011644 |
| SHTN1 | shootin 1 | -0.0116097 |
| GPC5 | glypican 5 | -0.0115531 |
| ARCN1 | archain 1 | -0.0115502 |
| KIAA1217 | KIAA1217 | -0.0115274 |
| TMEM263 | transmembrane protein 263 | -0.0114707 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0114601 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0114085 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.0114039 |
| VDAC1 | voltage-dependent anion channel 1 | -0.011313 |
| CCND1 | cyclin D1 | -0.0112789 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.01124 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0110638 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.011018 |
| RRBP1 | ribosome binding protein 1 | -0.0108104 |
| BET1 | Bet1 golgi vesicular membrane trafficking protein | -0.0107918 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0107074 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0106394 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0105401 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0104382 |
| FBXO22 | F-box protein 22 | -0.0103665 |
| LAMA4 | laminin, alpha 4 | -0.0102533 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.0102322 |
