| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Posaconazole perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Posaconazole_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SDK1 | sidekick cell adhesion molecule 1 | 0.148718 |
| FAM13A | family with sequence similarity 13, member A | 0.132494 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.130964 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0960308 |
| PRELID2 | PRELI domain containing 2 | 0.0883754 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0879918 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0830276 |
| GPC6 | glypican 6 | 0.081005 |
| NDRG1 | N-myc downstream regulated 1 | 0.0774323 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0771085 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0749697 |
| NAV2 | neuron navigator 2 | 0.0747722 |
| MEF2A | myocyte enhancer factor 2A | 0.0742649 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.071997 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0686763 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0682185 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0643845 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0580749 |
| SMAD3 | SMAD family member 3 | 0.0572149 |
| FLNB | filamin B, beta | 0.0568379 |
| RAD51B | RAD51 paralog B | 0.0559092 |
| NGLY1 | N-glycanase 1 | 0.0539062 |
| FAM20C | family with sequence similarity 20, member C | 0.0530445 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0526865 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0523077 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0515691 |
| LOX | lysyl oxidase | 0.0514151 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.050993 |
| ADD3 | adducin 3 (gamma) | 0.0501333 |
| CA12 | carbonic anhydrase XII | 0.0498507 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.049371 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0491383 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0488979 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0482484 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0478302 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0456413 |
| RARB | retinoic acid receptor, beta | 0.0456323 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0443726 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0438511 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0428715 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0415076 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0414961 |
| RUNX2 | runt-related transcription factor 2 | 0.040891 |
| HELZ | helicase with zinc finger | 0.0408531 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0405276 |
| ZNF292 | zinc finger protein 292 | 0.0404455 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0399565 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0379293 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0378928 |
| RAI14 | retinoic acid induced 14 | 0.0374568 |
| TSPAN5 | tetraspanin 5 | 0.03699 |
| SLTM | SAFB-like, transcription modulator | 0.0368134 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0366016 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.0363177 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0361414 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0359208 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0359128 |
| PHF21A | PHD finger protein 21A | 0.0358913 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0356521 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0355531 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0352477 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0344353 |
| DST | dystonin | 0.0343599 |
| PRR16 | proline rich 16 | 0.0330895 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0324691 |
| MECOM | MDS1 and EVI1 complex locus | 0.0324613 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0324571 |
| TLR2 | toll-like receptor 2 | 0.03233 |
| CEP250 | centrosomal protein 250kDa | 0.0322686 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0320206 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0311828 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0311072 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0311062 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0307552 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0306302 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0304631 |
| LDHA | lactate dehydrogenase A | 0.0302391 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0299527 |
| PFKP | phosphofructokinase, platelet | 0.0299057 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0298845 |
| ATXN1 | ataxin 1 | 0.0298232 |
| ANXA1 | annexin A1 | 0.0294155 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0293736 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0291541 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0289334 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0286207 |
| PLIN2 | perilipin 2 | 0.0285778 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0282346 |
| RBM39 | RNA binding motif protein 39 | 0.0280171 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.0280163 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0280138 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0277516 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0273005 |
| H1-0 | H1.0 linker histone | 0.027256 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0271748 |
| HDAC9 | histone deacetylase 9 | 0.0271622 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0270167 |
| ANGPTL4 | angiopoietin-like 4 | 0.0269978 |
| CCNL1 | cyclin L1 | 0.026643 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0265275 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.221453 |
| CD44 | CD44 molecule (Indian blood group) | -0.194195 |
| VIM | vimentin | -0.193514 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0911587 |
| PTMA | prothymosin, alpha | -0.0666346 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0649326 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0648553 |
| GLCCI1 | glucocorticoid induced 1 | -0.0587239 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0586337 |
| FTL | ferritin, light polypeptide | -0.0565923 |
| UBC | ubiquitin C | -0.0551762 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0535362 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0521855 |
| IER3 | immediate early response 3 | -0.0500629 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0491219 |
| OSMR | oncostatin M receptor | -0.049114 |
| POTEF | POTE ankyrin domain family, member F | -0.0460956 |
| KYNU | kynureninase | -0.044865 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0420258 |
| RPLP1 | ribosomal protein, large, P1 | -0.0414986 |
| RPS6 | ribosomal protein S6 | -0.0396809 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0394577 |
| AHNAK | AHNAK nucleoprotein | -0.0364275 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0361412 |
| HAS2 | hyaluronan synthase 2 | -0.0358806 |
| ACTG1 | actin gamma 1 | -0.0358367 |
| S100A6 | S100 calcium binding protein A6 | -0.0357979 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0357422 |
| GOLGA4 | golgin A4 | -0.0354591 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0349331 |
| STC1 | stanniocalcin 1 | -0.0343336 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0334527 |
| CCNI | cyclin I | -0.033025 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0319356 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0318985 |
| RPLP2 | ribosomal protein, large, P2 | -0.0318511 |
| MT2A | metallothionein 2A | -0.0315114 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0312521 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0311274 |
| RPS8 | ribosomal protein S8 | -0.0308297 |
| TMSB10 | thymosin beta 10 | -0.0285018 |
| RPS21 | ribosomal protein S21 | -0.0284613 |
| RPS24 | ribosomal protein S24 | -0.0282605 |
| NRP1 | neuropilin 1 | -0.0277348 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0273652 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0273302 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0272357 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0271548 |
| RPL28 | ribosomal protein L28 | -0.0265173 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0261368 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0259865 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.025674 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0254583 |
| IL1R1 | interleukin 1 receptor, type I | -0.0252574 |
| RPLP0 | ribosomal protein, large, P0 | -0.0247148 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0247105 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0242136 |
| RPS23 | ribosomal protein S23 | -0.0239432 |
| RPL32 | ribosomal protein L32 | -0.0238203 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0237042 |
| HMGA2 | high mobility group AT-hook 2 | -0.0236848 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0236186 |
| PKM | pyruvate kinase, muscle | -0.0236054 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0235474 |
| RPS16 | ribosomal protein S16 | -0.023402 |
| FNBP1 | formin binding protein 1 | -0.0229622 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0228376 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0225093 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0224253 |
| RBM25 | RNA binding motif protein 25 | -0.0223838 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0223617 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | -0.0221234 |
| FRMD5 | FERM domain containing 5 | -0.0221128 |
| S100A10 | S100 calcium binding protein A10 | -0.0217384 |
| SEPTIN7 | septin 7 | -0.0215414 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.021509 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | -0.021501 |
| TXNRD1 | thioredoxin reductase 1 | -0.0213561 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0210995 |
| RPS29 | ribosomal protein S29 | -0.0210541 |
| VRK2 | vaccinia related kinase 2 | -0.0207458 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0205236 |
| RPL34 | ribosomal protein L34 | -0.0204998 |
| BPTF | bromodomain PHD finger transcription factor | -0.0204713 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0201274 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0199704 |
| MARS1 | methionyl-tRNA synthetase 1 | -0.0199316 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0197776 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.0197768 |
| KIAA1217 | KIAA1217 | -0.0197423 |
| PARD3 | par-3 family cell polarity regulator | -0.0197053 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0195691 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0194767 |
| NTN4 | netrin 4 | -0.0194442 |
| RPL19 | ribosomal protein L19 | -0.0194267 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0192508 |
| GRAMD1B | GRAM domain containing 1B | -0.0192239 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0192171 |
| CDCP1 | CUB domain containing protein 1 | -0.0191767 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0191491 |
