| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Posaconazole perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Posaconazole_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INHBA | inhibin, beta A | 0.12334 |
| NDRG1 | N-myc downstream regulated 1 | 0.0933682 |
| FN1 | fibronectin 1 | 0.0894582 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0798438 |
| MYO10 | myosin X | 0.0794223 |
| OXR1 | oxidation resistance 1 | 0.0739655 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0730515 |
| STC1 | stanniocalcin 1 | 0.07156 |
| DST | dystonin | 0.0707113 |
| ASPH | aspartate beta-hydroxylase | 0.0673747 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0633648 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0623634 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0616731 |
| VIM | vimentin | 0.059924 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0583204 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.058043 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0555824 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.054367 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0528861 |
| COG5 | component of oligomeric golgi complex 5 | 0.0523904 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0522178 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0510789 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0505179 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0499844 |
| HLA-A | major histocompatibility complex, class I, A | 0.0491807 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0486839 |
| PRKCA | protein kinase C, alpha | 0.0479808 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0479369 |
| RTN4 | reticulon 4 | 0.0473783 |
| PHF3 | PHD finger protein 3 | 0.0472181 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0467982 |
| FAT1 | FAT atypical cadherin 1 | 0.0457475 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0452289 |
| MORF4L2 | mortality factor 4 like 2 | 0.0451996 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0449368 |
| MMP1 | matrix metallopeptidase 1 | 0.0448702 |
| FAM13A | family with sequence similarity 13, member A | 0.044633 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0441914 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0439832 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0435948 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0432801 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.042747 |
| VMP1 | vacuole membrane protein 1 | 0.0422563 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0421348 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0419397 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0416136 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.041471 |
| RIGI | RNA sensor RIG-I | 0.0413987 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0399553 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0399143 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0389379 |
| YEATS2 | YEATS domain containing 2 | 0.0384959 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0383348 |
| PLS3 | plastin 3 | 0.0383068 |
| LMO7 | LIM domain 7 | 0.0382942 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0374928 |
| TPM4 | tropomyosin 4 | 0.0371523 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0370698 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0369237 |
| RNF145 | ring finger protein 145 | 0.0366182 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.036421 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0361608 |
| HLA-B | major histocompatibility complex, class I, B | 0.0355446 |
| SUCO | SUN domain containing ossification factor | 0.0355302 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0354486 |
| H1-0 | H1.0 linker histone | 0.0354222 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0353886 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0352488 |
| CALU | calumenin | 0.0351862 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.0349011 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0348058 |
| ENO1 | enolase 1, (alpha) | 0.0346013 |
| YBX3 | Y box binding protein 3 | 0.0345292 |
| NEK7 | NIMA-related kinase 7 | 0.0345217 |
| SETD5 | SET domain containing 5 | 0.0341519 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0336046 |
| MTSS1 | metastasis suppressor 1 | 0.0329158 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0326076 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0324357 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0323471 |
| PGK1 | phosphoglycerate kinase 1 | 0.0322947 |
| KYNU | kynureninase | 0.0316981 |
| CANX | calnexin | 0.0310536 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0308221 |
| RPS4X | ribosomal protein S4, X-linked | 0.0307325 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0298259 |
| COL5A2 | collagen, type V, alpha 2 | 0.0296162 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0295607 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0290931 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0290393 |
| PTEN | phosphatase and tensin homolog | 0.0285043 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0285007 |
| RPS3 | ribosomal protein S3 | 0.0284048 |
| NME7 | NME/NM23 family member 7 | 0.028387 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0280784 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0280134 |
| AFF1 | AF4/FMR2 family, member 1 | 0.027956 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0278225 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0277362 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0276101 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.180948 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.177069 |
| MT2A | metallothionein 2A | -0.13857 |
| FTL | ferritin, light polypeptide | -0.125765 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.107605 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.104789 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0911335 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0778347 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0720867 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0697133 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0684226 |
| FLNB | filamin B, beta | -0.0675305 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0658757 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0633256 |
| RPS16 | ribosomal protein S16 | -0.0626651 |
| CCND1 | cyclin D1 | -0.0602132 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0580435 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0573433 |
| POTEF | POTE ankyrin domain family, member F | -0.0563639 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0556564 |
| GOLGA4 | golgin A4 | -0.0542099 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0537389 |
| FBXO11 | F-box protein 11 | -0.0536931 |
| RAB10 | RAB10, member RAS oncogene family | -0.0534083 |
| SFTPA2 | surfactant protein A2 | -0.052543 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0495057 |
| RSF1 | remodeling and spacing factor 1 | -0.0482941 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0478451 |
| RPL31 | ribosomal protein L31 | -0.0476682 |
| SBF2 | SET binding factor 2 | -0.0474318 |
| C3 | complement component 3 | -0.0465612 |
| SLTM | SAFB-like, transcription modulator | -0.0462946 |
| RPLP1 | ribosomal protein, large, P1 | -0.0449943 |
| TXNRD1 | thioredoxin reductase 1 | -0.0449323 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0438186 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0435214 |
| RPLP2 | ribosomal protein, large, P2 | -0.0431112 |
| STK24 | serine/threonine kinase 24 | -0.0429443 |
| EXOC4 | exocyst complex component 4 | -0.0426136 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0422082 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0419467 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0414775 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0410212 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0408685 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0402595 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0400396 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0398023 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0391637 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0387627 |
| EGFR | epidermal growth factor receptor | -0.0379929 |
| CD109 | CD109 molecule | -0.0379118 |
| PAPOLA | poly(A) polymerase alpha | -0.0376511 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0374499 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0370253 |
| OLA1 | Obg-like ATPase 1 | -0.036835 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0367038 |
| RPS19 | ribosomal protein S19 | -0.0364809 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.036474 |
| C1D | C1D nuclear receptor corepressor | -0.0364515 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0360824 |
| NF1 | neurofibromin 1 | -0.0359716 |
| DIAPH3 | diaphanous-related formin 3 | -0.0359074 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0358311 |
| RNF213 | ring finger protein 213 | -0.0357373 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.035685 |
| SNX9 | sorting nexin 9 | -0.035549 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0351862 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0348846 |
| SVIL | supervillin | -0.0344237 |
| SNX14 | sorting nexin 14 | -0.0343206 |
| GLIS3 | GLIS family zinc finger 3 | -0.0342523 |
| RPL11 | ribosomal protein L11 | -0.0340727 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0339841 |
| SQSTM1 | sequestosome 1 | -0.0335401 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0332737 |
| NUP58 | nucleoporin 58 | -0.0330799 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0325919 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0322919 |
| EXOC6B | exocyst complex component 6B | -0.0321448 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0321357 |
| TMSB10 | thymosin beta 10 | -0.0321092 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0320477 |
| TXNIP | thioredoxin interacting protein | -0.0320174 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.03159 |
| CDK17 | cyclin-dependent kinase 17 | -0.031584 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0315401 |
| RBM25 | RNA binding motif protein 25 | -0.0314566 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0313005 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0311569 |
| RPS14 | ribosomal protein S14 | -0.0305996 |
| RPL35A | ribosomal protein L35a | -0.0305823 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0305803 |
| KIAA1217 | KIAA1217 | -0.0305143 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0303832 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0303703 |
| S100A6 | S100 calcium binding protein A6 | -0.0301881 |
| MMP12 | matrix metallopeptidase 12 | -0.0300066 |
| SEPTIN7 | septin 7 | -0.0298911 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0295681 |
| CCDC88A | coiled-coil domain containing 88A | -0.0295107 |
