| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Posaconazole perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Posaconazole_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EFNA5 | ephrin-A5 | 0.155964 |
| MYOF | myoferlin | 0.133934 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.119216 |
| DST | dystonin | 0.104744 |
| ASPH | aspartate beta-hydroxylase | 0.104018 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.100279 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0958706 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0951385 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0932183 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0925832 |
| GDA | guanine deaminase | 0.0916695 |
| FLNB | filamin B, beta | 0.0906073 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0799157 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0793469 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0767261 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0737391 |
| TXNRD1 | thioredoxin reductase 1 | 0.0716586 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0696824 |
| NEK7 | NIMA-related kinase 7 | 0.0676061 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0676002 |
| FN1 | fibronectin 1 | 0.0673896 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0662434 |
| MCL1 | myeloid cell leukemia 1 | 0.0625115 |
| PGK1 | phosphoglycerate kinase 1 | 0.0609719 |
| SPAG9 | sperm associated antigen 9 | 0.059315 |
| FAM13A | family with sequence similarity 13, member A | 0.0557676 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0552531 |
| OGA | O-GlcNAcase | 0.0544141 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0529513 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0517599 |
| EZR | ezrin | 0.0504506 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0500507 |
| NRCAM | neuronal cell adhesion molecule | 0.0489801 |
| CD109 | CD109 molecule | 0.0489671 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0477076 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0472773 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.047175 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0463371 |
| RTN4 | reticulon 4 | 0.0462607 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0461421 |
| ANXA1 | annexin A1 | 0.0460809 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0458317 |
| ENO1 | enolase 1, (alpha) | 0.0448515 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0441714 |
| RBM39 | RNA binding motif protein 39 | 0.0431016 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0423809 |
| TMSB10 | thymosin beta 10 | 0.0423092 |
| NDRG1 | N-myc downstream regulated 1 | 0.0421237 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0418824 |
| LDHA | lactate dehydrogenase A | 0.0414942 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0397192 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0395858 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0395366 |
| CENPF | centromere protein F, 350/400kDa | 0.0391179 |
| NBAS | neuroblastoma amplified sequence | 0.0389092 |
| SMYD3 | SET and MYND domain containing 3 | 0.0381833 |
| CTSC | cathepsin C | 0.0376429 |
| ATXN1 | ataxin 1 | 0.0375222 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0374253 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0373914 |
| FTL | ferritin, light polypeptide | 0.0373389 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0370876 |
| PCBP2 | poly(rC) binding protein 2 | 0.036825 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0364045 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0361717 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0361295 |
| GRAMD1B | GRAM domain containing 1B | 0.0358667 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0357084 |
| MT2A | metallothionein 2A | 0.0354798 |
| USP34 | ubiquitin specific peptidase 34 | 0.0353552 |
| CTBP2 | C-terminal binding protein 2 | 0.0352583 |
| PCBP3 | poly(rC) binding protein 3 | 0.035257 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.03517 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0351562 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0349527 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0349412 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0349201 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0347555 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0343388 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0337777 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0335738 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0335167 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0334104 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0333934 |
| PHF21A | PHD finger protein 21A | 0.0333332 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0330741 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0329286 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0323905 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0322686 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0321683 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0320531 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.031391 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0312232 |
| MORF4L2 | mortality factor 4 like 2 | 0.0312184 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.031073 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0309382 |
| CALU | calumenin | 0.0307926 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0306671 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0305145 |
| ZNF292 | zinc finger protein 292 | 0.0299906 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.132851 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.130576 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0905113 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0751586 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0692453 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0591513 |
| RPS6 | ribosomal protein S6 | -0.0552364 |
| PTMA | prothymosin, alpha | -0.0457307 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0443373 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0400698 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0365525 |
| ACTG1 | actin gamma 1 | -0.0345634 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0343566 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0325381 |
| RPS8 | ribosomal protein S8 | -0.0323675 |
| RPS24 | ribosomal protein S24 | -0.0321607 |
| HLA-B | major histocompatibility complex, class I, B | -0.0298729 |
| RPL36A | ribosomal protein L36a | -0.0288456 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0286589 |
| RPS23 | ribosomal protein S23 | -0.0273881 |
| ASTN2 | astrotactin 2 | -0.0271806 |
| CDH13 | cadherin 13 | -0.0269387 |
| INHBA | inhibin, beta A | -0.026697 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0264929 |
| CD44 | CD44 molecule (Indian blood group) | -0.0248439 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0247593 |
| STC1 | stanniocalcin 1 | -0.023632 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | -0.02352 |
| RPL31 | ribosomal protein L31 | -0.0220057 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0219747 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0217204 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0212936 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0210227 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0205122 |
| KIAA0825 | KIAA0825 | -0.0203399 |
| CADM2 | cell adhesion molecule 2 | -0.0200119 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0197823 |
| R3HDM2 | R3H domain containing 2 | -0.019678 |
| S100A10 | S100 calcium binding protein A10 | -0.0194114 |
| RPL26 | ribosomal protein L26 | -0.0191946 |
| PCDH9 | protocadherin 9 | -0.0190508 |
| RPL39 | ribosomal protein L39 | -0.0189809 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0187663 |
| RPS27 | ribosomal protein S27 | -0.0186432 |
| RANBP17 | RAN binding protein 17 | -0.0186306 |
| POTEF | POTE ankyrin domain family, member F | -0.0184504 |
| RPS16 | ribosomal protein S16 | -0.0182517 |
| CUX1 | cut-like homeobox 1 | -0.0182194 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0177235 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0173767 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0172865 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0170688 |
| SMAD2 | SMAD family member 2 | -0.0168166 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0167625 |
| RPL8 | ribosomal protein L8 | -0.0164114 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0164087 |
| RPL28 | ribosomal protein L28 | -0.0161607 |
| LSAMP | limbic system-associated membrane protein | -0.0160999 |
| IL6 | interleukin 6 | -0.0157529 |
| RPS29 | ribosomal protein S29 | -0.0154185 |
| CHL1 | cell adhesion molecule L1-like | -0.0152649 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0152551 |
| RPLP2 | ribosomal protein, large, P2 | -0.0152021 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0149808 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0149249 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0149071 |
| PCED1B | PC-esterase domain containing 1B | -0.0147678 |
| HLA-A | major histocompatibility complex, class I, A | -0.0146391 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0145647 |
| AEBP2 | AE binding protein 2 | -0.0145614 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | -0.014415 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0141766 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0141209 |
| PCDH15 | protocadherin-related 15 | -0.0139635 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.0139411 |
| RPS14 | ribosomal protein S14 | -0.0138474 |
| HDAC8 | histone deacetylase 8 | -0.0135625 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.013482 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0134275 |
| MAP1B | microtubule-associated protein 1B | -0.0133647 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0132139 |
| RPS28 | ribosomal protein S28 | -0.0132105 |
| RPS25 | ribosomal protein S25 | -0.0132036 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0131924 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0129458 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0129165 |
| ESM1 | endothelial cell-specific molecule 1 | -0.0128936 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | -0.0128638 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0125928 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.01236 |
| RPS15 | ribosomal protein S15 | -0.0122548 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0121989 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0121973 |
| RPLP1 | ribosomal protein, large, P1 | -0.012183 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0120641 |
| TBCA | tubulin folding cofactor A | -0.0120461 |
| RPS27A | ribosomal protein S27a | -0.0119799 |
| RASAL2 | RAS protein activator like 2 | -0.0119058 |
| ATP9B | ATPase, class II, type 9B | -0.0115871 |
| SUMF1 | sulfatase modifying factor 1 | -0.0115466 |
