| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Posaconazole perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Posaconazole_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.14219 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.109544 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0882245 |
| HELZ | helicase with zinc finger | 0.0874279 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0867209 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0856193 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0817888 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0817583 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0804326 |
| COL5A2 | collagen, type V, alpha 2 | 0.0749635 |
| PGK1 | phosphoglycerate kinase 1 | 0.0748817 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0733995 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0729926 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0723073 |
| DST | dystonin | 0.072169 |
| LDHA | lactate dehydrogenase A | 0.0710836 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.069148 |
| ENO1 | enolase 1, (alpha) | 0.0683863 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.067977 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0675407 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0666033 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.066396 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0655423 |
| FLNB | filamin B, beta | 0.0617988 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0613785 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0586473 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0586122 |
| COPA | coatomer protein complex, subunit alpha | 0.0579235 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0570626 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0566718 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0540737 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0507123 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0496722 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0490467 |
| SET | SET nuclear proto-oncogene | 0.0478653 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0466782 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0462045 |
| VCL | vinculin | 0.0458024 |
| ZNF292 | zinc finger protein 292 | 0.0452587 |
| PDE10A | phosphodiesterase 10A | 0.0449716 |
| FN1 | fibronectin 1 | 0.0448916 |
| MED13L | mediator complex subunit 13-like | 0.0445634 |
| SPAG9 | sperm associated antigen 9 | 0.0443309 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0439684 |
| RBM39 | RNA binding motif protein 39 | 0.043532 |
| CENPF | centromere protein F, 350/400kDa | 0.0430986 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0423105 |
| PHF21A | PHD finger protein 21A | 0.0421842 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0419506 |
| ERBIN | erbb2 interacting protein | 0.0419367 |
| RPL11 | ribosomal protein L11 | 0.041162 |
| GPC6 | glypican 6 | 0.0407247 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0407084 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0396843 |
| STC1 | stanniocalcin 1 | 0.0385293 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0384424 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0384197 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.037707 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0376367 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0371206 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.037104 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0368429 |
| MYO10 | myosin X | 0.0355021 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0350368 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0349442 |
| EZR | ezrin | 0.0345915 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0345455 |
| PRDX1 | peroxiredoxin 1 | 0.0340154 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0333941 |
| SMYD3 | SET and MYND domain containing 3 | 0.0333748 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0330175 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0327597 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0310978 |
| MKI67 | marker of proliferation Ki-67 | 0.0307586 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0303094 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0303051 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0302091 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0300897 |
| ATXN2 | ataxin 2 | 0.0296437 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0293172 |
| RPL26 | ribosomal protein L26 | 0.028721 |
| MYOF | myoferlin | 0.0284601 |
| RPS14 | ribosomal protein S14 | 0.0283849 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0278205 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0272791 |
| SEPTIN7 | septin 7 | 0.0268927 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0266224 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0262401 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0261669 |
| GLG1 | golgi glycoprotein 1 | 0.0256565 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0254517 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.025165 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0243887 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0241903 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0241864 |
| RORA | RAR-related orphan receptor A | 0.0236803 |
| GOLGB1 | golgin B1 | 0.0236771 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0234083 |
| RTN4 | reticulon 4 | 0.0223407 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0212891 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.333284 |
| VIM | vimentin | -0.116958 |
| EGFR | epidermal growth factor receptor | -0.115814 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.113566 |
| EFNA5 | ephrin-A5 | -0.107566 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.103119 |
| MYO1E | myosin IE | -0.0926381 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0900468 |
| LAMB3 | laminin, beta 3 | -0.089976 |
| LAMC2 | laminin, gamma 2 | -0.0811058 |
| LAMA4 | laminin, alpha 4 | -0.0800791 |
| RPL15 | ribosomal protein L15 | -0.0797181 |
| RPS13 | ribosomal protein S13 | -0.0732014 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0713205 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0708038 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0649556 |
| SLTM | SAFB-like, transcription modulator | -0.0640336 |
| RPL37 | ribosomal protein L37 | -0.0636093 |
| AREG | amphiregulin | -0.0629781 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0603667 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0603206 |
| EGR1 | early growth response 1 | -0.0597562 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0593746 |
| RPL12 | ribosomal protein L12 | -0.0591842 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0586779 |
| TMSB10 | thymosin beta 10 | -0.0579232 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0569162 |
| ACTG1 | actin gamma 1 | -0.0560491 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0556826 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.05554 |
| TOP1 | topoisomerase (DNA) I | -0.0554667 |
| CDH13 | cadherin 13 | -0.0554069 |
| RPS23 | ribosomal protein S23 | -0.0550787 |
| ITGA6 | integrin, alpha 6 | -0.0540286 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0532614 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0531406 |
| RPS4X | ribosomal protein S4, X-linked | -0.0529514 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0529062 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0522818 |
| YAP1 | Yes-associated protein 1 | -0.0520805 |
| RPS24 | ribosomal protein S24 | -0.0520278 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0518902 |
| FHIT | fragile histidine triad | -0.0514575 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0505912 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0505499 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0500705 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0497707 |
| PTMA | prothymosin, alpha | -0.0495049 |
| OLA1 | Obg-like ATPase 1 | -0.0487153 |
| PRKCA | protein kinase C, alpha | -0.0476573 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.045983 |
| RPL34 | ribosomal protein L34 | -0.0457461 |
| PTK2 | protein tyrosine kinase 2 | -0.0453717 |
| HMGA2 | high mobility group AT-hook 2 | -0.0443497 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0429627 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0428981 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0427099 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.042019 |
| LMO7 | LIM domain 7 | -0.0391484 |
| RPS16 | ribosomal protein S16 | -0.0390061 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0369406 |
| PARD3 | par-3 family cell polarity regulator | -0.0361882 |
| GPHN | gephyrin | -0.0360143 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0327811 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0327693 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.032713 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0323806 |
| SEPTIN2 | septin 2 | -0.0319346 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0319271 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0313606 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0310957 |
| RPL23 | ribosomal protein L23 | -0.0310381 |
| CANX | calnexin | -0.0309709 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0307917 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0305502 |
| HDLBP | high density lipoprotein binding protein | -0.0303308 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0299883 |
| RPL37A | ribosomal protein L37a | -0.0299869 |
| IER3 | immediate early response 3 | -0.027749 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0269506 |
| RPL31 | ribosomal protein L31 | -0.026569 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.026192 |
| PRELID2 | PRELI domain containing 2 | -0.0252846 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0251683 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0243074 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0240164 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0235584 |
| PCBP2 | poly(rC) binding protein 2 | -0.0233685 |
| RPL32 | ribosomal protein L32 | -0.0230061 |
| H3-3B | H3.3 histone B | -0.0227956 |
| STK24 | serine/threonine kinase 24 | -0.0223819 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0216893 |
| ANXA2 | annexin A2 | -0.0214997 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0210758 |
| CDK13 | cyclin-dependent kinase 13 | -0.0209353 |
| FNIP1 | folliculin interacting protein 1 | -0.0207658 |
| FTL | ferritin, light polypeptide | -0.0207639 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0206824 |
| VMP1 | vacuole membrane protein 1 | -0.0205914 |
| RPLP0 | ribosomal protein, large, P0 | -0.020548 |
