| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Posaconazole perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Posaconazole_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL5A2 | collagen, type V, alpha 2 | 0.0846371 |
| DST | dystonin | 0.0770724 |
| H1-0 | H1.0 linker histone | 0.0611869 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0581516 |
| HDAC9 | histone deacetylase 9 | 0.0514195 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.043818 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0402337 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0401075 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0397741 |
| THBS1 | thrombospondin 1 | 0.0383953 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0362468 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0352676 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0335107 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.0320844 |
| PDGFC | platelet derived growth factor C | 0.0311401 |
| NCKAP1 | NCK-associated protein 1 | 0.0310252 |
| COL3A1 | collagen, type III, alpha 1 | 0.030576 |
| GASK1B | golgi associated kinase 1B | 0.0303018 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0298793 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.029825 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0292611 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0292066 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0289351 |
| XPO1 | exportin 1 | 0.0288498 |
| ZNF217 | zinc finger protein 217 | 0.027095 |
| ANXA1 | annexin A1 | 0.0269087 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0266085 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0260106 |
| CFL2 | cofilin 2 (muscle) | 0.0257252 |
| STAG2 | stromal antigen 2 | 0.025328 |
| HBP1 | HMG-box transcription factor 1 | 0.025184 |
| PRELID2 | PRELI domain containing 2 | 0.023952 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0239304 |
| RIGI | RNA sensor RIG-I | 0.023333 |
| PCDH18 | protocadherin 18 | 0.0230319 |
| TM7SF3 | transmembrane 7 superfamily member 3 | 0.0227017 |
| ANXA5 | annexin A5 | 0.0226909 |
| USP3 | ubiquitin specific peptidase 3 | 0.0221382 |
| RBM26 | RNA binding motif protein 26 | 0.0219553 |
| ANKRD50 | ankyrin repeat domain 50 | 0.0218699 |
| EPHA3 | EPH receptor A3 | 0.0216167 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.021442 |
| PROS1 | protein S (alpha) | 0.0214079 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0213823 |
| ANLN | anillin, actin binding protein | 0.0213755 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0213061 |
| YAP1 | Yes-associated protein 1 | 0.0212053 |
| SUCO | SUN domain containing ossification factor | 0.020981 |
| SNX13 | sorting nexin 13 | 0.0208561 |
| CUL4B | cullin 4B | 0.0203799 |
| LDHA | lactate dehydrogenase A | 0.0199416 |
| ACTN4 | actinin, alpha 4 | 0.0199221 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0199057 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0199032 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0198173 |
| ARF4 | ADP-ribosylation factor 4 | 0.0195129 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.0194529 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0191224 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0190077 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0189664 |
| NFIB | nuclear factor I/B | 0.0188954 |
| PRKD1 | protein kinase D1 | 0.0188381 |
| TTK | TTK protein kinase | 0.0187293 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0183348 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0182634 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0181495 |
| MSN | moesin | 0.0179976 |
| CDK17 | cyclin-dependent kinase 17 | 0.0179454 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0178921 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0176824 |
| NPTN | neuroplastin | 0.0174318 |
| SEC24D | SEC24 family member D | 0.0171874 |
| FGFR1OP2 | FGFR1 oncogene partner 2 | 0.0169116 |
| NTM | neurotrimin | 0.016875 |
| PCBP2 | poly(rC) binding protein 2 | 0.0168201 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0168002 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0167829 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0166622 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0166564 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0166236 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0166102 |
| ATL2 | atlastin GTPase 2 | 0.0166057 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0164382 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.01643 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.016343 |
| PAXBP1 | PAX3 and PAX7 binding protein 1 | 0.0163342 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0163044 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0162994 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0162729 |
| ATF6 | activating transcription factor 6 | 0.0162269 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.0161966 |
| MYO6 | myosin VI | 0.0159535 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0158934 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0158397 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.0158271 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0158195 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.0157924 |
| RAB10 | RAB10, member RAS oncogene family | 0.0156918 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0156665 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0155656 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.20515 |
| COL11A1 | collagen, type XI, alpha 1 | -0.171344 |
| CADM2 | cell adhesion molecule 2 | -0.159883 |
| TMSB10 | thymosin beta 10 | -0.150254 |
| PTMA | prothymosin, alpha | -0.132478 |
| RPS16 | ribosomal protein S16 | -0.114107 |
| RPS6 | ribosomal protein S6 | -0.100569 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0985197 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0966806 |
| RPS8 | ribosomal protein S8 | -0.0921889 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0877187 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0842066 |
| JMJD1C | jumonji domain containing 1C | -0.0766698 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0726679 |
| COL1A2 | collagen, type I, alpha 2 | -0.0726475 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0721778 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0702647 |
| LRRC4C | leucine rich repeat containing 4C | -0.0699483 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0661842 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0622555 |
| RPL37A | ribosomal protein L37a | -0.0621203 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0616552 |
| RPL35A | ribosomal protein L35a | -0.0611899 |
| RPLP1 | ribosomal protein, large, P1 | -0.0607203 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0601381 |
| ACTG1 | actin gamma 1 | -0.0600119 |
| PHIP | pleckstrin homology domain interacting protein | -0.0598004 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0595623 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0595091 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0565796 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0564914 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0536022 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0535662 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0532358 |
| GNAS | GNAS complex locus | -0.0528405 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0527462 |
| GPC3 | glypican 3 | -0.0527089 |
| SRP54 | signal recognition particle 54kDa | -0.0518777 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0511728 |
| SMYD3 | SET and MYND domain containing 3 | -0.0502696 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.048754 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0482574 |
| PFN1 | profilin 1 | -0.0479337 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0475729 |
| PRTG | protogenin | -0.0474927 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0473679 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0473217 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0471693 |
| RPL23 | ribosomal protein L23 | -0.046934 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0463627 |
| RPL11 | ribosomal protein L11 | -0.0459488 |
| RPL12 | ribosomal protein L12 | -0.0442661 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0435224 |
| RPL5 | ribosomal protein L5 | -0.0433185 |
| RPL37 | ribosomal protein L37 | -0.0426338 |
| FTL | ferritin, light polypeptide | -0.0424591 |
| MAP4 | microtubule-associated protein 4 | -0.0421841 |
| RPS12 | ribosomal protein S12 | -0.0411148 |
| RPS3 | ribosomal protein S3 | -0.0410777 |
| FBXO17 | F-box protein 17 | -0.0410047 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0409488 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0404465 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0403586 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0403094 |
| LYST | lysosomal trafficking regulator | -0.0399843 |
| CCDC88A | coiled-coil domain containing 88A | -0.0397349 |
| ITGAV | integrin, alpha V | -0.0395907 |
| TOX | thymocyte selection-associated high mobility group box | -0.0394039 |
| RPL19 | ribosomal protein L19 | -0.0391507 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0389807 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0389711 |
| PEG10 | paternally expressed 10 | -0.0389232 |
| NEBL | nebulette | -0.0388486 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0384592 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.038127 |
| RPLP2 | ribosomal protein, large, P2 | -0.0379317 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0376298 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0374952 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0374319 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0371245 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0370798 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0367247 |
| SNX6 | sorting nexin 6 | -0.0365358 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0362777 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0361196 |
| RPL31 | ribosomal protein L31 | -0.035933 |
| TENM3 | teneurin transmembrane protein 3 | -0.0357918 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0351842 |
| RPS13 | ribosomal protein S13 | -0.0351656 |
| ANKRD12 | ankyrin repeat domain 12 | -0.034773 |
| RPL36A | ribosomal protein L36a | -0.0345787 |
| TMSB4X | thymosin beta 4, X-linked | -0.0343938 |
| CUX1 | cut-like homeobox 1 | -0.0342676 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0339326 |
| TUBA1B | tubulin, alpha 1b | -0.0337679 |
| APOE | apolipoprotein E | -0.0336087 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0336032 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0335495 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0335229 |
| WASF2 | WAS protein family, member 2 | -0.0333841 |
