| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Posaconazole perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Posaconazole_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.388567 |
| DST | dystonin | 0.152697 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.152337 |
| FN1 | fibronectin 1 | 0.141175 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.140597 |
| COL6A3 | collagen, type VI, alpha 3 | 0.128814 |
| PDE10A | phosphodiesterase 10A | 0.108246 |
| FNDC3B | fibronectin type III domain containing 3B | 0.103526 |
| FRMD4A | FERM domain containing 4A | 0.0983377 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0973831 |
| MYOF | myoferlin | 0.0873443 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0798288 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0778914 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0748442 |
| CADM1 | cell adhesion molecule 1 | 0.0745596 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0693871 |
| TNS3 | tensin 3 | 0.0651814 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0635958 |
| LDHA | lactate dehydrogenase A | 0.0635953 |
| NAV2 | neuron navigator 2 | 0.0595716 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0568577 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0565859 |
| BICC1 | BicC family RNA binding protein 1 | 0.0544104 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0529904 |
| SFTPA2 | surfactant protein A2 | 0.0511414 |
| VCAN | versican | 0.0498884 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.049657 |
| FNIP1 | folliculin interacting protein 1 | 0.0496424 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0460731 |
| ATXN1 | ataxin 1 | 0.0459215 |
| PHF21A | PHD finger protein 21A | 0.0456741 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0442805 |
| RAI14 | retinoic acid induced 14 | 0.0441407 |
| FBXO32 | F-box protein 32 | 0.0439877 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0437448 |
| FLNB | filamin B, beta | 0.0432957 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0415531 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0412024 |
| PGK1 | phosphoglycerate kinase 1 | 0.0410022 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.040775 |
| ENO1 | enolase 1, (alpha) | 0.0401487 |
| CCNL1 | cyclin L1 | 0.0394154 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0391352 |
| SMAD3 | SMAD family member 3 | 0.038878 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0385582 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0383657 |
| FMNL2 | formin-like 2 | 0.0382415 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0377924 |
| ZNF292 | zinc finger protein 292 | 0.0373187 |
| SQSTM1 | sequestosome 1 | 0.0369365 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0363606 |
| PLIN2 | perilipin 2 | 0.0360121 |
| PRELID2 | PRELI domain containing 2 | 0.0355356 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0350997 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.034952 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0344983 |
| HELZ | helicase with zinc finger | 0.0344895 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0343323 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0340093 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0337594 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.033274 |
| FAM13A | family with sequence similarity 13, member A | 0.0332191 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0319625 |
| LRRC7 | leucine rich repeat containing 7 | 0.0315249 |
| OGA | O-GlcNAcase | 0.0313257 |
| QKI | QKI, KH domain containing, RNA binding | 0.0312802 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0311781 |
| INSIG1 | insulin induced gene 1 | 0.031003 |
| RNF213 | ring finger protein 213 | 0.0301113 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0298128 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0293443 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0289904 |
| MX1 | MX dynamin-like GTPase 1 | 0.0286993 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0285706 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0283955 |
| CENPF | centromere protein F, 350/400kDa | 0.0281194 |
| AFDN | afadin, adherens junction formation factor | 0.0279039 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0278663 |
| PCBP2 | poly(rC) binding protein 2 | 0.0277617 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0271327 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0269159 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0262864 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.026178 |
| SCARB1 | scavenger receptor class B, member 1 | 0.0256504 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0256478 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0255239 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.02533 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0253275 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0250728 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0249585 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0248403 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0247644 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0246932 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0245234 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0243668 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0237444 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0235824 |
| CTSB | cathepsin B | 0.0234855 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0234431 |
| CD109 | CD109 molecule | 0.0231772 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.229095 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.126514 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0797495 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0748374 |
| CD44 | CD44 molecule (Indian blood group) | -0.0739059 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0673074 |
| GLIS3 | GLIS family zinc finger 3 | -0.062029 |
| HMGA2 | high mobility group AT-hook 2 | -0.049622 |
| RPS6 | ribosomal protein S6 | -0.0475685 |
| IER3 | immediate early response 3 | -0.046088 |
| STC1 | stanniocalcin 1 | -0.0428646 |
| ACTG1 | actin gamma 1 | -0.0425165 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0393703 |
| HLA-B | major histocompatibility complex, class I, B | -0.0392987 |
| DEK | DEK proto-oncogene | -0.0391437 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0366471 |
| RPS24 | ribosomal protein S24 | -0.0359607 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0347635 |
| RPL36A | ribosomal protein L36a | -0.034688 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0340276 |
| RPS8 | ribosomal protein S8 | -0.032604 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0325606 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0309608 |
| RPLP2 | ribosomal protein, large, P2 | -0.0297404 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0288742 |
| PTMA | prothymosin, alpha | -0.0287065 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0286241 |
| RPL5 | ribosomal protein L5 | -0.0285863 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.027167 |
| RPLP1 | ribosomal protein, large, P1 | -0.026727 |
| MT2A | metallothionein 2A | -0.0257533 |
| MAP1B | microtubule-associated protein 1B | -0.0251535 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0250594 |
| SRGN | serglycin | -0.024797 |
| RPS21 | ribosomal protein S21 | -0.0243637 |
| OSMR | oncostatin M receptor | -0.0240797 |
| RPS23 | ribosomal protein S23 | -0.0234958 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.023249 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0227958 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0226101 |
| RPL26 | ribosomal protein L26 | -0.0225668 |
| CDH13 | cadherin 13 | -0.0216535 |
| RPS10 | ribosomal protein S10 | -0.0215023 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0212192 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0207356 |
| RPL28 | ribosomal protein L28 | -0.0203577 |
| POTEF | POTE ankyrin domain family, member F | -0.020185 |
| JMJD1C | jumonji domain containing 1C | -0.0201583 |
| CTSD | cathepsin D | -0.0200296 |
| RPL9 | ribosomal protein L9 | -0.0199626 |
| CAVIN1 | caveolae associated protein 1 | -0.019476 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0193275 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0184109 |
| FLOT1 | flotillin 1 | -0.0182279 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0180817 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0179655 |
| GPC6 | glypican 6 | -0.0179428 |
| TMSB10 | thymosin beta 10 | -0.0178776 |
| CDCP1 | CUB domain containing protein 1 | -0.0175797 |
| HLA-E | major histocompatibility complex, class I, E | -0.0175762 |
| SYAP1 | synapse associated protein 1 | -0.0171861 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0171611 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0169318 |
| ASTN2 | astrotactin 2 | -0.0168328 |
| RPLP0 | ribosomal protein, large, P0 | -0.0166353 |
| RPS15 | ribosomal protein S15 | -0.0158071 |
| TRIM56 | tripartite motif containing 56 | -0.0156216 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0154731 |
| IL6 | interleukin 6 | -0.0153535 |
| GSTO1 | glutathione S-transferase omega 1 | -0.0148551 |
| SDC4 | syndecan 4 | -0.0145882 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0144142 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0143443 |
| RPL38 | ribosomal protein L38 | -0.0142865 |
| HMGB1 | high mobility group box 1 | -0.0142631 |
| RPL34 | ribosomal protein L34 | -0.01426 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0141259 |
| RRBP1 | ribosome binding protein 1 | -0.0140792 |
| TMSB4X | thymosin beta 4, X-linked | -0.0140767 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0139901 |
| RPL27A | ribosomal protein L27a | -0.0139781 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0139742 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0139584 |
| S100A9 | S100 calcium binding protein A9 | -0.0139319 |
| TUBB | tubulin, beta class I | -0.013879 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0138587 |
| LMNA | lamin A/C | -0.0138551 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0138469 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0136517 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0135718 |
| PKM | pyruvate kinase, muscle | -0.013558 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0135536 |
| THOC2 | THO complex 2 | -0.0134413 |
| CEP112 | centrosomal protein 112kDa | -0.0134259 |
| MT1X | metallothionein 1X | -0.0133535 |
| INHBA | inhibin, beta A | -0.0133471 |
| SEPTIN7 | septin 7 | -0.0132612 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0130681 |
| RPS27A | ribosomal protein S27a | -0.0130605 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0129971 |
