| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Posaconazole perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Posaconazole_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.14547 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.137487 |
| FNDC3B | fibronectin type III domain containing 3B | 0.111651 |
| NDRG1 | N-myc downstream regulated 1 | 0.106631 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.100333 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0915038 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0877704 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0862381 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0839524 |
| CD44 | CD44 molecule (Indian blood group) | 0.0761301 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0748713 |
| LDHA | lactate dehydrogenase A | 0.0673564 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0665278 |
| PGK1 | phosphoglycerate kinase 1 | 0.0653327 |
| ENO1 | enolase 1, (alpha) | 0.0625876 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0614329 |
| FAM13A | family with sequence similarity 13, member A | 0.0567852 |
| PRELID2 | PRELI domain containing 2 | 0.0559146 |
| FNIP1 | folliculin interacting protein 1 | 0.0554061 |
| CD109 | CD109 molecule | 0.0547953 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0544958 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0446433 |
| ANLN | anillin, actin binding protein | 0.0442618 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0437135 |
| ZNF292 | zinc finger protein 292 | 0.0432819 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0421618 |
| CANX | calnexin | 0.0415895 |
| RAD51B | RAD51 paralog B | 0.0407785 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0406041 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0396524 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0392147 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0391324 |
| ZNF395 | zinc finger protein 395 | 0.0390938 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0387701 |
| ATP13A3 | ATPase type 13A3 | 0.0382789 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0382507 |
| SPAG9 | sperm associated antigen 9 | 0.0381739 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.037674 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0375489 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0372974 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.036835 |
| ARRDC3 | arrestin domain containing 3 | 0.0366037 |
| ANXA5 | annexin A5 | 0.0365406 |
| EGR1 | early growth response 1 | 0.0362354 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0356964 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0353898 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0347796 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0344666 |
| NRXN3 | neurexin 3 | 0.0341865 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0341107 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0340856 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0338399 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0337148 |
| HDAC9 | histone deacetylase 9 | 0.0330439 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0330189 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0329373 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0323118 |
| XPO1 | exportin 1 | 0.0312984 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0312909 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0309607 |
| RND3 | Rho family GTPase 3 | 0.0307082 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0305907 |
| ADM | adrenomedullin | 0.0305325 |
| DST | dystonin | 0.0302489 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.029926 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0294536 |
| MORF4L2 | mortality factor 4 like 2 | 0.0292716 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0291431 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.02878 |
| VEGFA | vascular endothelial growth factor A | 0.028779 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0286238 |
| GLUL | glutamate-ammonia ligase | 0.0282955 |
| MT2A | metallothionein 2A | 0.0281483 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0280767 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0276827 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0272727 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0271928 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0271153 |
| INSIG2 | insulin induced gene 2 | 0.0270748 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0269765 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0269113 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0268484 |
| NAV2 | neuron navigator 2 | 0.0266966 |
| PHF21A | PHD finger protein 21A | 0.0266113 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0263561 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0263323 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0258296 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0255521 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.025084 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0242256 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.024139 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0241388 |
| ASPH | aspartate beta-hydroxylase | 0.0240298 |
| EZR | ezrin | 0.0238618 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0237796 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0237093 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0236085 |
| TPD52 | tumor protein D52 | 0.0235036 |
| NBAS | neuroblastoma amplified sequence | 0.0233886 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0230479 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.1245 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.118948 |
| HLA-B | major histocompatibility complex, class I, B | -0.102096 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0999602 |
| HMGA2 | high mobility group AT-hook 2 | -0.0720818 |
| GLIS3 | GLIS family zinc finger 3 | -0.0659276 |
| TMSB10 | thymosin beta 10 | -0.0524189 |
| CALD1 | caldesmon 1 | -0.0488146 |
| COL5A1 | collagen, type V, alpha 1 | -0.0457445 |
| FN1 | fibronectin 1 | -0.0445092 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0439001 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.038761 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0382137 |
| PRSS23 | protease, serine, 23 | -0.0366181 |
| RASAL2 | RAS protein activator like 2 | -0.0356534 |
| COL1A2 | collagen, type I, alpha 2 | -0.0344639 |
| ACTG1 | actin gamma 1 | -0.0338777 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0336159 |
| RRBP1 | ribosome binding protein 1 | -0.0335403 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0332623 |
| CLTC | clathrin, heavy chain (Hc) | -0.0329412 |
| USP34 | ubiquitin specific peptidase 34 | -0.0322534 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0320138 |
| TNNC1 | troponin C type 1 (slow) | -0.0310221 |
| CDH13 | cadherin 13 | -0.0304085 |
| NKTR | natural killer cell triggering receptor | -0.0290793 |
| VCL | vinculin | -0.0290409 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0281694 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0277577 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0271474 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.026897 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | -0.0268251 |
| LOXL2 | lysyl oxidase-like 2 | -0.0266184 |
| HLA-C | major histocompatibility complex, class I, C | -0.026303 |
| RBM25 | RNA binding motif protein 25 | -0.0261041 |
| HIP1 | huntingtin interacting protein 1 | -0.0260415 |
| CDK13 | cyclin-dependent kinase 13 | -0.0255676 |
| NECTIN3 | nectin cell adhesion molecule 3 | -0.0252686 |
| CDK6 | cyclin-dependent kinase 6 | -0.0249886 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0249252 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0246475 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0242099 |
| CAVIN1 | caveolae associated protein 1 | -0.0241231 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0238998 |
| ZNF609 | zinc finger protein 609 | -0.0238199 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0236225 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0227712 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0226787 |
| SERF2 | small EDRK-rich factor 2 | -0.0225549 |
| FBXW11 | F-box and WD repeat domain containing 11 | -0.0224045 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0223142 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0222107 |
| PMM2 | phosphomannomutase 2 | -0.0220351 |
| COL3A1 | collagen, type III, alpha 1 | -0.0219633 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0219537 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0218437 |
| S100A6 | S100 calcium binding protein A6 | -0.0217756 |
| CALU | calumenin | -0.0215793 |
| MAP4 | microtubule-associated protein 4 | -0.0214533 |
| MRTFA | myocardin related transcription factor A | -0.0214392 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0213479 |
| RSU1 | Ras suppressor protein 1 | -0.021209 |
| OSMR | oncostatin M receptor | -0.0209606 |
| ANTXR2 | anthrax toxin receptor 2 | -0.020724 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0200721 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0198294 |
| COG5 | component of oligomeric golgi complex 5 | -0.0198135 |
| AHNAK | AHNAK nucleoprotein | -0.0197944 |
| SYNPO | synaptopodin | -0.0196711 |
| OGA | O-GlcNAcase | -0.0196091 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0195953 |
| SCFD2 | sec1 family domain containing 2 | -0.0194504 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0191798 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0191011 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0190472 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0189833 |
| FBN1 | fibrillin 1 | -0.0189566 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0189514 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0189398 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0189267 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0187737 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0184342 |
| GLG1 | golgi glycoprotein 1 | -0.0182948 |
| TAGLN2 | transgelin 2 | -0.0182935 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0181442 |
| INHBA | inhibin, beta A | -0.0181371 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0180353 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.0179338 |
| POTEF | POTE ankyrin domain family, member F | -0.0178011 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0177842 |
| EFNA5 | ephrin-A5 | -0.0177815 |
| SNX6 | sorting nexin 6 | -0.0176226 |
| E2F7 | E2F transcription factor 7 | -0.0175997 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0175097 |
| UBAP2 | ubiquitin associated protein 2 | -0.0174938 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0173567 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0173447 |
| EHBP1 | EH domain binding protein 1 | -0.0172264 |
| ZNF133 | zinc finger protein 133 | -0.0172149 |
| COL1A1 | collagen, type I, alpha 1 | -0.0171013 |
