| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pravastatin (sodium)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.256754 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.170915 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.109709 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.101704 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0885167 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0737718 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0710838 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0677157 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0675341 |
| OGA | O-GlcNAcase | 0.0558163 |
| AUTS2 | autism susceptibility candidate 2 | 0.0537813 |
| ATP13A3 | ATPase type 13A3 | 0.053426 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0528897 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0527045 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0499635 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0492711 |
| LOXL2 | lysyl oxidase-like 2 | 0.0471452 |
| SBF2 | SET binding factor 2 | 0.0471305 |
| DST | dystonin | 0.047081 |
| B2M | beta-2-microglobulin | 0.0452777 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0439964 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0433977 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0429561 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0420773 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0409248 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0394892 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0387551 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.038258 |
| AHNAK | AHNAK nucleoprotein | 0.0372844 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.037121 |
| FMNL2 | formin-like 2 | 0.0370372 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0368969 |
| FBN1 | fibrillin 1 | 0.0367206 |
| MT2A | metallothionein 2A | 0.036642 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0353814 |
| MYOF | myoferlin | 0.0346436 |
| FRMD5 | FERM domain containing 5 | 0.0346247 |
| VIM | vimentin | 0.0344975 |
| CD109 | CD109 molecule | 0.0340922 |
| SEPTIN9 | septin 9 | 0.0340027 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0339457 |
| AFDN | afadin, adherens junction formation factor | 0.0337209 |
| OPTN | optineurin | 0.0335587 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0334555 |
| NAV2 | neuron navigator 2 | 0.0333694 |
| DENND5A | DENN/MADD domain containing 5A | 0.0333572 |
| COPA | coatomer protein complex, subunit alpha | 0.0328484 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0326445 |
| FRMD4A | FERM domain containing 4A | 0.0319769 |
| MYADM | myeloid-associated differentiation marker | 0.0310403 |
| RNF24 | ring finger protein 24 | 0.0307281 |
| FNIP1 | folliculin interacting protein 1 | 0.0306634 |
| COL1A2 | collagen, type I, alpha 2 | 0.0305103 |
| RNF145 | ring finger protein 145 | 0.0295955 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0295024 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.029178 |
| KIF13A | kinesin family member 13A | 0.0288742 |
| ABI1 | abl-interactor 1 | 0.0288656 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0284861 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0282872 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0282463 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0282401 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0280603 |
| HDAC9 | histone deacetylase 9 | 0.0279232 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0278463 |
| WTAP | Wilms tumor 1 associated protein | 0.0270224 |
| RAI1 | retinoic acid induced 1 | 0.0266743 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.0266084 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0263511 |
| TRIM56 | tripartite motif containing 56 | 0.0261178 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0257951 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0255275 |
| NKTR | natural killer cell triggering receptor | 0.0254903 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.02511 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0250416 |
| SETD5 | SET domain containing 5 | 0.0249364 |
| FAM193B | family with sequence similarity 193, member B | 0.0248354 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0242486 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0238278 |
| KIFAP3 | kinesin-associated protein 3 | 0.0237902 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0237411 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0234389 |
| FLNB | filamin B, beta | 0.0231958 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0231513 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | 0.0231497 |
| ZNF292 | zinc finger protein 292 | 0.0229255 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0228475 |
| YEATS2 | YEATS domain containing 2 | 0.0226232 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0223084 |
| APP | amyloid beta (A4) precursor protein | 0.022192 |
| UBXN4 | UBX domain protein 4 | 0.0221706 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0219914 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | 0.0219627 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0219292 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.021748 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.021608 |
| GPC6 | glypican 6 | 0.0214913 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0213853 |
| MSI2 | musashi RNA-binding protein 2 | 0.0212957 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0212248 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.381523 |
| TMSB10 | thymosin beta 10 | -0.163646 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.156361 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.106111 |
| S100A10 | S100 calcium binding protein A10 | -0.077298 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0735041 |
| MAP1B | microtubule-associated protein 1B | -0.0686745 |
| CCND1 | cyclin D1 | -0.0677762 |
| PODXL | podocalyxin-like | -0.0599944 |
| LOX | lysyl oxidase | -0.0590024 |
| ANXA2 | annexin A2 | -0.0587133 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0521647 |
| HLA-B | major histocompatibility complex, class I, B | -0.0520832 |
| NDRG1 | N-myc downstream regulated 1 | -0.0473102 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0446314 |
| RPL35A | ribosomal protein L35a | -0.0405213 |
| ARF1 | ADP-ribosylation factor 1 | -0.0397352 |
| COL5A1 | collagen, type V, alpha 1 | -0.0394738 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0390962 |
| ACTG1 | actin gamma 1 | -0.0388965 |
| PLAT | plasminogen activator, tissue | -0.0386709 |
| HLA-C | major histocompatibility complex, class I, C | -0.038276 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0382612 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0380602 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0376107 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0366267 |
| POTEF | POTE ankyrin domain family, member F | -0.0353836 |
| TPM4 | tropomyosin 4 | -0.035248 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.034415 |
| THBS2 | thrombospondin 2 | -0.0343885 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0342208 |
| RIGI | RNA sensor RIG-I | -0.0339764 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0328674 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0325671 |
| VCL | vinculin | -0.0324311 |
| EGR1 | early growth response 1 | -0.0309291 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0302035 |
| BSG | basigin (Ok blood group) | -0.0301696 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0294365 |
| RPLP1 | ribosomal protein, large, P1 | -0.0285982 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0285925 |
| RPL28 | ribosomal protein L28 | -0.0283875 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0283079 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0282646 |
| FSTL1 | follistatin-like 1 | -0.0276751 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0274306 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0268527 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0267555 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0267448 |
| CD99 | CD99 molecule | -0.0266758 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0263966 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0262678 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.0258125 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0256309 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0256017 |
| HDLBP | high density lipoprotein binding protein | -0.025586 |
| CTSD | cathepsin D | -0.0253678 |
| FN1 | fibronectin 1 | -0.0250621 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0250322 |
| RPL32 | ribosomal protein L32 | -0.0249276 |
| RPS15 | ribosomal protein S15 | -0.0247505 |
| FTL | ferritin, light polypeptide | -0.0243934 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0241886 |
| HMGB1 | high mobility group box 1 | -0.0240424 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0238145 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0235224 |
| OSMR | oncostatin M receptor | -0.0234553 |
| RPL34 | ribosomal protein L34 | -0.0234222 |
| MTDH | metadherin | -0.0233046 |
| CDH13 | cadherin 13 | -0.0228425 |
| RRBP1 | ribosome binding protein 1 | -0.022611 |
| TAGLN2 | transgelin 2 | -0.0225118 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0223559 |
| FUS | FUS RNA binding protein | -0.022335 |
| TXNRD1 | thioredoxin reductase 1 | -0.0220449 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.021814 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0217097 |
| RBM39 | RNA binding motif protein 39 | -0.0214947 |
| IL7R | interleukin 7 receptor | -0.0213213 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0212717 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0211182 |
| EFNA5 | ephrin-A5 | -0.0210628 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0210347 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0209602 |
| MEIS2 | Meis homeobox 2 | -0.02084 |
| MT1X | metallothionein 1X | -0.0206585 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.020628 |
| TUBB | tubulin, beta class I | -0.0204654 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0203604 |
| JUN | jun proto-oncogene | -0.0203564 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.0203156 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0200938 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0200324 |
| NPR2 | natriuretic peptide receptor 2 | -0.0199659 |
| TENM3 | teneurin transmembrane protein 3 | -0.0198302 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | -0.0194305 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -0.0193969 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.01937 |
| PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | -0.0193599 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0193314 |
