| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pravastatin (sodium)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SMAD3 | SMAD family member 3 | 0.10859 |
| MT2A | metallothionein 2A | 0.0853114 |
| RPLP1 | ribosomal protein, large, P1 | 0.0827413 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0778309 |
| RPS19 | ribosomal protein S19 | 0.0747342 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0726967 |
| ASPH | aspartate beta-hydroxylase | 0.0619059 |
| RPS12 | ribosomal protein S12 | 0.0581693 |
| RPS6 | ribosomal protein S6 | 0.0580089 |
| RPL23 | ribosomal protein L23 | 0.0528779 |
| FTL | ferritin, light polypeptide | 0.0519346 |
| RPL37A | ribosomal protein L37a | 0.051891 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.050151 |
| RPS17 | ribosomal protein S17 | 0.0501138 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0499493 |
| RPS3 | ribosomal protein S3 | 0.0494075 |
| RPL26 | ribosomal protein L26 | 0.0480066 |
| RPS8 | ribosomal protein S8 | 0.0459057 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0447733 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0438797 |
| FMNL2 | formin-like 2 | 0.0428591 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.042293 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0388416 |
| TOP1 | topoisomerase (DNA) I | 0.037221 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0372061 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0355645 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0338411 |
| PTMA | prothymosin, alpha | 0.0338228 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0336899 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0332634 |
| RPL31 | ribosomal protein L31 | 0.0326504 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0321903 |
| RASA2 | RAS p21 protein activator 2 | 0.0321323 |
| RACK1 | receptor for activated C kinase 1 | 0.0319379 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0318612 |
| FAM107B | family with sequence similarity 107, member B | 0.0317103 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.031533 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0314513 |
| RPS24 | ribosomal protein S24 | 0.0304711 |
| SPAG9 | sperm associated antigen 9 | 0.0292777 |
| OGA | O-GlcNAcase | 0.0292318 |
| PDE10A | phosphodiesterase 10A | 0.0284867 |
| RPS27A | ribosomal protein S27a | 0.0283458 |
| NUP58 | nucleoporin 58 | 0.0276841 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0274519 |
| RPS4X | ribosomal protein S4, X-linked | 0.0273018 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0272873 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0269102 |
| ECT2 | epithelial cell transforming 2 | 0.0268548 |
| SET | SET nuclear proto-oncogene | 0.0267074 |
| USP3 | ubiquitin specific peptidase 3 | 0.0265446 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.026454 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0255245 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.025413 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.025391 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0253466 |
| RPL18 | ribosomal protein L18 | 0.0247861 |
| ATP13A3 | ATPase type 13A3 | 0.0243507 |
| RPL4 | ribosomal protein L4 | 0.0237632 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.023727 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0237203 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0236628 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0235058 |
| MCL1 | myeloid cell leukemia 1 | 0.0233181 |
| RPS2 | ribosomal protein S2 | 0.0232495 |
| EREG | epiregulin | 0.0231928 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0231577 |
| DENND1A | DENN/MADD domain containing 1A | 0.0231472 |
| RPLP2 | ribosomal protein, large, P2 | 0.0226604 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0221425 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.022107 |
| RPL19 | ribosomal protein L19 | 0.0218828 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0216733 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0212829 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0211872 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0211861 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0211717 |
| ANKRD33B | ankyrin repeat domain 33B | 0.021087 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.021048 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0210435 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0209434 |
| RUNX1 | runt-related transcription factor 1 | 0.0209177 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0205465 |
| OLA1 | Obg-like ATPase 1 | 0.0204763 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0203377 |
| RPL9 | ribosomal protein L9 | 0.0203201 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0202658 |
| RTN4 | reticulon 4 | 0.0202057 |
| WWOX | WW domain containing oxidoreductase | 0.0200539 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0199816 |
| RRM2 | ribonucleotide reductase M2 | 0.0199661 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0199377 |
| TMSB4X | thymosin beta 4, X-linked | 0.0198279 |
| NCKAP1 | NCK-associated protein 1 | 0.0193701 |
| MYOF | myoferlin | 0.0193575 |
| CBX3 | chromobox homolog 3 | 0.0193447 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0191109 |
| KLF6 | Kruppel-like factor 6 | 0.0190967 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0190622 |
| RPL27 | ribosomal protein L27 | 0.0189465 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.184038 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.183189 |
| NDRG1 | N-myc downstream regulated 1 | -0.17197 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.107747 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.100163 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0957079 |
| EFNA5 | ephrin-A5 | -0.0843069 |
| ACTG1 | actin gamma 1 | -0.0842263 |
| CA12 | carbonic anhydrase XII | -0.0809312 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0718805 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0693929 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0685389 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0674768 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0633895 |
| GOLGB1 | golgin B1 | -0.0632875 |
| ANXA2 | annexin A2 | -0.0619098 |
| EGFR | epidermal growth factor receptor | -0.0613587 |
| EHBP1 | EH domain binding protein 1 | -0.0611721 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.058439 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0565929 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.053734 |
| RNF213 | ring finger protein 213 | -0.0533872 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0521535 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0516949 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0510899 |
| MYO1E | myosin IE | -0.0509258 |
| MYADM | myeloid-associated differentiation marker | -0.0496234 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0482066 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0452786 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0449495 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0428515 |
| HDLBP | high density lipoprotein binding protein | -0.0421423 |
| RAI14 | retinoic acid induced 14 | -0.0421247 |
| KRT81 | keratin 81, type II | -0.0419467 |
| RND3 | Rho family GTPase 3 | -0.0419295 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0418541 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0415715 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0415446 |
| JMJD1C | jumonji domain containing 1C | -0.0413713 |
| CANX | calnexin | -0.0404585 |
| MAP1B | microtubule-associated protein 1B | -0.0404173 |
| EGR1 | early growth response 1 | -0.0397535 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0385743 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.038574 |
| POTEF | POTE ankyrin domain family, member F | -0.0376773 |
| HMGA1 | high mobility group AT-hook 1 | -0.0375203 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0373506 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0373351 |
| LDHA | lactate dehydrogenase A | -0.0371391 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0360213 |
| GOLGA4 | golgin A4 | -0.0357833 |
| CLTC | clathrin, heavy chain (Hc) | -0.0350249 |
| CALU | calumenin | -0.0341 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0339046 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0336769 |
| MORF4L2 | mortality factor 4 like 2 | -0.0332782 |
| WASF2 | WAS protein family, member 2 | -0.033177 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0327766 |
| USP34 | ubiquitin specific peptidase 34 | -0.0327516 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0327079 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0316591 |
| NRP1 | neuropilin 1 | -0.0315816 |
| FNIP1 | folliculin interacting protein 1 | -0.0315276 |
| LOC112694756 | uncharaterized LOC112694756 | -0.031418 |
| RHCG | Rh family, C glycoprotein | -0.0312953 |
| CCDC88A | coiled-coil domain containing 88A | -0.030629 |
| CLINT1 | clathrin interactor 1 | -0.0302792 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0300645 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0300363 |
| MYO9A | myosin IXA | -0.0295881 |
| GLG1 | golgi glycoprotein 1 | -0.0295703 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0294957 |
| ZNF609 | zinc finger protein 609 | -0.0293926 |
| CD99 | CD99 molecule | -0.0284601 |
| OSMR | oncostatin M receptor | -0.0281929 |
| GOSR1 | golgi SNAP receptor complex member 1 | -0.0275759 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0274236 |
| COPA | coatomer protein complex, subunit alpha | -0.027406 |
| PARD3 | par-3 family cell polarity regulator | -0.0273836 |
| MAP4 | microtubule-associated protein 4 | -0.0273664 |
| TNS3 | tensin 3 | -0.0271072 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0268958 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0266743 |
| ADM | adrenomedullin | -0.0265279 |
| GLIS3 | GLIS family zinc finger 3 | -0.0263124 |
| TCF12 | transcription factor 12 | -0.0262918 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0261054 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0260634 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0258645 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0258488 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0257805 |
| NF1 | neurofibromin 1 | -0.02547 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0254534 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0253092 |
| RIN2 | Ras and Rab interactor 2 | -0.0251909 |
| FBXO11 | F-box protein 11 | -0.0251403 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0251101 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0250205 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0246328 |
| PRKCA | protein kinase C, alpha | -0.0243941 |
