| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pravastatin (sodium)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MEST | mesoderm specific transcript | 0.235023 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0984386 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0728309 |
| PCBP2 | poly(rC) binding protein 2 | 0.0707459 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0690717 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0686318 |
| QKI | QKI, KH domain containing, RNA binding | 0.0671912 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.059573 |
| NFIB | nuclear factor I/B | 0.0551023 |
| PNN | pinin, desmosome associated protein | 0.0527531 |
| TPX2 | TPX2, microtubule-associated | 0.0525246 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0517147 |
| VIM | vimentin | 0.050879 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0505564 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0501205 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0488768 |
| VEGFA | vascular endothelial growth factor A | 0.0473221 |
| ZNF292 | zinc finger protein 292 | 0.0450644 |
| CBX3 | chromobox homolog 3 | 0.0448237 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0429676 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0429009 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0428449 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0423457 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0421585 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0417116 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0404751 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0398137 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0382288 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0382266 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.03774 |
| RPS2 | ribosomal protein S2 | 0.0368957 |
| RTN4 | reticulon 4 | 0.0360735 |
| RBM25 | RNA binding motif protein 25 | 0.0358709 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0357959 |
| RLF | rearranged L-myc fusion | 0.0356511 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0356509 |
| RPL13A | ribosomal protein L13a | 0.0353681 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0353023 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0351479 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0350241 |
| NBAS | neuroblastoma amplified sequence | 0.0348877 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0346837 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0345056 |
| RPS12 | ribosomal protein S12 | 0.0344466 |
| TPD52 | tumor protein D52 | 0.0340736 |
| LMNB1 | lamin B1 | 0.0338959 |
| SMAP1 | small ArfGAP 1 | 0.0331892 |
| GOLGA4 | golgin A4 | 0.0330297 |
| HELZ | helicase with zinc finger | 0.0329077 |
| PDS5B | PDS5 cohesin associated factor B | 0.03257 |
| FRMD6 | FERM domain containing 6 | 0.0322786 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0321809 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0320168 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.031742 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0316149 |
| CASC3 | cancer susceptibility candidate 3 | 0.0314258 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.031425 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0314062 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0313164 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0307625 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | 0.0306291 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.030294 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0301548 |
| TOP1 | topoisomerase (DNA) I | 0.0300747 |
| WAC | WW domain containing adaptor with coiled-coil | 0.029932 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0299209 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.029678 |
| VMP1 | vacuole membrane protein 1 | 0.0292092 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0291542 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0291497 |
| HACE1 | HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 | 0.0291198 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0287698 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0287674 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0283673 |
| CDK19 | cyclin-dependent kinase 19 | 0.0283084 |
| MALSU1 | mitochondrial assembly of ribosomal large subunit 1 | 0.0282043 |
| OFD1 | oral-facial-digital syndrome 1 | 0.0281455 |
| RO60 | Ro60, Y RNA binding protein | 0.0281116 |
| FAM13A | family with sequence similarity 13, member A | 0.0278192 |
| FMNL2 | formin-like 2 | 0.0276101 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0275785 |
| YBX1 | Y box binding protein 1 | 0.0275683 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 0.0274334 |
| HDGFL3 | HDGF like 3 | 0.0272309 |
| DENND4C | DENN/MADD domain containing 4C | 0.0272265 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0272249 |
| MYO10 | myosin X | 0.027205 |
| XPO1 | exportin 1 | 0.0270829 |
| NUP58 | nucleoporin 58 | 0.0270598 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0270109 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0269777 |
| TXNL1 | thioredoxin-like 1 | 0.0269335 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0269111 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0268459 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0267421 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0265815 |
| DIAPH1 | diaphanous-related formin 1 | 0.0265146 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0265111 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0265021 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0262736 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.114633 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.114399 |
| PEG10 | paternally expressed 10 | -0.0729482 |
| CADM2 | cell adhesion molecule 2 | -0.0707705 |
| FTL | ferritin, light polypeptide | -0.070124 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0700104 |
| ACTG1 | actin gamma 1 | -0.0613895 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.0603856 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0572308 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0560003 |
| RPL35A | ribosomal protein L35a | -0.0554 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0531028 |
| EGR1 | early growth response 1 | -0.0526999 |
| IER3 | immediate early response 3 | -0.0513754 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.051255 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0497413 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0488459 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0473265 |
| CUX1 | cut-like homeobox 1 | -0.0466724 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.045636 |
| TCF12 | transcription factor 12 | -0.0455602 |
| HMGA1 | high mobility group AT-hook 1 | -0.0451971 |
| RPS25 | ribosomal protein S25 | -0.0447435 |
| RPS23 | ribosomal protein S23 | -0.0442882 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0440615 |
| IGF2 | insulin-like growth factor 2 | -0.0425709 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0419217 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0416981 |
| HELLS | helicase, lymphoid-specific | -0.0415022 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.04133 |
| RPL11 | ribosomal protein L11 | -0.0408133 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | -0.0398276 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0395887 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0385008 |
| RPL37 | ribosomal protein L37 | -0.038467 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0383538 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0383525 |
| FBXO11 | F-box protein 11 | -0.0381706 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0381235 |
| LOC112694756 | uncharaterized LOC112694756 | -0.037692 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0376615 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0374568 |
| INTS6 | integrator complex subunit 6 | -0.0371004 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.0364794 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0362253 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.035606 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0350912 |
| HMGB1 | high mobility group box 1 | -0.0347047 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0343787 |
| TPM4 | tropomyosin 4 | -0.0342514 |
| SH3PXD2B | SH3 and PX domains 2B | -0.0342477 |
| MYOF | myoferlin | -0.0335917 |
| AK1 | adenylate kinase 1 | -0.0335619 |
| CDK13 | cyclin-dependent kinase 13 | -0.0332828 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.032927 |
| HDAC8 | histone deacetylase 8 | -0.0327946 |
| RPL34 | ribosomal protein L34 | -0.0327007 |
| NF1 | neurofibromin 1 | -0.0326204 |
| FOXO3 | forkhead box O3 | -0.0322536 |
| DEK | DEK proto-oncogene | -0.0320779 |
| RPL31 | ribosomal protein L31 | -0.0317085 |
| FUS | FUS RNA binding protein | -0.0317022 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0315233 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0312066 |
| DENND1A | DENN/MADD domain containing 1A | -0.0311818 |
| PTMA | prothymosin, alpha | -0.0308353 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0308297 |
| FN1 | fibronectin 1 | -0.0306814 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.03058 |
| TMSB10 | thymosin beta 10 | -0.030191 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0301814 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0300717 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0300078 |
| EXOC4 | exocyst complex component 4 | -0.0299456 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0294816 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.0293621 |
| TUBB | tubulin, beta class I | -0.0289091 |
| RSU1 | Ras suppressor protein 1 | -0.02887 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0288611 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0288159 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0287477 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0286645 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0280098 |
| CENPP | centromere protein P | -0.0277678 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0277126 |
| BPTF | bromodomain PHD finger transcription factor | -0.0275056 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.027101 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0270871 |
| E2F3 | E2F transcription factor 3 | -0.027087 |
| RPS15 | ribosomal protein S15 | -0.0268359 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0267635 |
| TJP1 | tight junction protein 1 | -0.0267123 |
| ATG10 | autophagy related 10 | -0.0265764 |
| CCND1 | cyclin D1 | -0.0263979 |
| LIPG | lipase, endothelial | -0.0263064 |
| RPS27A | ribosomal protein S27a | -0.026112 |
| FAM193A | family with sequence similarity 193, member A | -0.0259804 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0259124 |
| SOBP | sine oculis binding protein homolog (Drosophila) | -0.0258626 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0258385 |
