| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pravastatin (sodium)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.251082 |
| FLNB | filamin B, beta | 0.14703 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.140906 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.121863 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.1215 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.119084 |
| SMAD3 | SMAD family member 3 | 0.0640592 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0594533 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0578752 |
| EFNA5 | ephrin-A5 | 0.0548827 |
| RPS3 | ribosomal protein S3 | 0.0538749 |
| RPL37A | ribosomal protein L37a | 0.0532577 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0517225 |
| VIM | vimentin | 0.0493411 |
| OGA | O-GlcNAcase | 0.0488245 |
| RBM25 | RNA binding motif protein 25 | 0.0469258 |
| ASPH | aspartate beta-hydroxylase | 0.0455028 |
| RPS12 | ribosomal protein S12 | 0.0452301 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0442887 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0439587 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0425654 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0415674 |
| TOP1 | topoisomerase (DNA) I | 0.0409213 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0406632 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0399511 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0398462 |
| CAPRIN2 | caprin family member 2 | 0.0396622 |
| RPS8 | ribosomal protein S8 | 0.0389674 |
| NCKAP1 | NCK-associated protein 1 | 0.0387817 |
| STK39 | serine threonine kinase 39 | 0.038231 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.038097 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0371005 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0355101 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0352231 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0349512 |
| TMEM41B | transmembrane protein 41B | 0.0349394 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0341873 |
| RPL26 | ribosomal protein L26 | 0.0334969 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.032763 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0320656 |
| ATP13A3 | ATPase type 13A3 | 0.0313051 |
| AHNAK | AHNAK nucleoprotein | 0.0311073 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0310779 |
| SLTM | SAFB-like, transcription modulator | 0.0309263 |
| LMTK2 | lemur tyrosine kinase 2 | 0.030724 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0305313 |
| EPCAM | epithelial cell adhesion molecule | 0.0302524 |
| THOC2 | THO complex 2 | 0.0298308 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0294075 |
| PTK2 | protein tyrosine kinase 2 | 0.0292516 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0291572 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0280711 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0275351 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0272393 |
| PLEC | plectin | 0.026999 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0269823 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0265963 |
| AFDN | afadin, adherens junction formation factor | 0.0263479 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0261883 |
| ZNF292 | zinc finger protein 292 | 0.0260633 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0254511 |
| SLMAP | sarcolemma associated protein | 0.0248901 |
| RPS2 | ribosomal protein S2 | 0.0247197 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0246336 |
| SBF2 | SET binding factor 2 | 0.0246239 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0243261 |
| RALB | v-ral simian leukemia viral oncogene homolog B | 0.0241027 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0240114 |
| VMP1 | vacuole membrane protein 1 | 0.0239964 |
| ITGA6 | integrin, alpha 6 | 0.0239526 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0236195 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0234421 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0233946 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0232242 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0231645 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0230305 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0229318 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0229022 |
| SET | SET nuclear proto-oncogene | 0.0228218 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0225167 |
| CCNY | cyclin Y | 0.0224697 |
| NEK7 | NIMA-related kinase 7 | 0.0224569 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0224316 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0223914 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0223397 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0222419 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0221526 |
| RUNX1 | runt-related transcription factor 1 | 0.0218602 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0218564 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0216778 |
| ACVR1 | activin A receptor, type I | 0.0215785 |
| SERINC1 | serine incorporator 1 | 0.0215212 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0213684 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0213246 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0212829 |
| SERTAD2 | SERTA domain containing 2 | 0.0211518 |
| RTN4 | reticulon 4 | 0.0208077 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0207755 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0205667 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0204637 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.285317 |
| NDRG1 | N-myc downstream regulated 1 | -0.131957 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.131398 |
| MUC17 | mucin 17, cell surface associated | -0.12576 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.12317 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.118732 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.10282 |
| HMGA1 | high mobility group AT-hook 1 | -0.100906 |
| TXNIP | thioredoxin interacting protein | -0.0970853 |
| POTEF | POTE ankyrin domain family, member F | -0.0910539 |
| UBC | ubiquitin C | -0.0892584 |
| EGR1 | early growth response 1 | -0.0872538 |
| FTL | ferritin, light polypeptide | -0.0846043 |
| DSG2 | desmoglein 2 | -0.0781517 |
| MXD1 | MAX dimerization protein 1 | -0.0769732 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0762397 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0742739 |
| ANXA2 | annexin A2 | -0.0686021 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0675463 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.067446 |
| LDHA | lactate dehydrogenase A | -0.0671982 |
| TXNRD1 | thioredoxin reductase 1 | -0.0643688 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0639269 |
| S100A10 | S100 calcium binding protein A10 | -0.0633726 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0597793 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0582615 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0576664 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0520611 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.051804 |
| CALU | calumenin | -0.0515318 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0499125 |
| MORF4L2 | mortality factor 4 like 2 | -0.0466626 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0451624 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0441211 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0437325 |
| ARF4 | ADP-ribosylation factor 4 | -0.0436564 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0423254 |
| FBXO11 | F-box protein 11 | -0.0420705 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0402805 |
| TMSB10 | thymosin beta 10 | -0.0383347 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0374427 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0373904 |
| RRBP1 | ribosome binding protein 1 | -0.0364987 |
| MYO1E | myosin IE | -0.0349317 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0348253 |
| SP100 | SP100 nuclear antigen | -0.033859 |
| RNF213 | ring finger protein 213 | -0.0338287 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0336914 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0336081 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0332278 |
| PGK1 | phosphoglycerate kinase 1 | -0.032719 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0327146 |
| ARF1 | ADP-ribosylation factor 1 | -0.0326184 |
| KLK10 | kallikrein-related peptidase 10 | -0.0325821 |
| TRRAP | transformation/transcription domain-associated protein | -0.0325608 |
| ENO1 | enolase 1, (alpha) | -0.0321984 |
| PKM | pyruvate kinase, muscle | -0.0320098 |
| RIGI | RNA sensor RIG-I | -0.031388 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0308216 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0307642 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0303921 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.030348 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0301452 |
| RPL8 | ribosomal protein L8 | -0.0299628 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0298812 |
| KRT19 | keratin 19, type I | -0.0295195 |
| LAMA4 | laminin, alpha 4 | -0.0294059 |
| FAM3C | family with sequence similarity 3, member C | -0.0291816 |
| EMP1 | epithelial membrane protein 1 | -0.028848 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.028294 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0282852 |
| RIOK3 | RIO kinase 3 | -0.0281343 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0278239 |
| SEC24A | SEC24 family member A | -0.0277627 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0274089 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0271773 |
| ITGB4 | integrin, beta 4 | -0.0268135 |
| RPL35A | ribosomal protein L35a | -0.0263753 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0262434 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0262129 |
| ERBIN | erbb2 interacting protein | -0.0258691 |
| ARPC3 | actin related protein 2/3 complex, subunit 3, 21kDa | -0.0258049 |
| FUS | FUS RNA binding protein | -0.0257281 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0255556 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0255495 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0255168 |
| RHOA | ras homolog family member A | -0.0254192 |
| TOB1 | transducer of ERBB2, 1 | -0.0253914 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0253263 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0252525 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0251449 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0250569 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0250496 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0250416 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0248515 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0245 |
| LAMB3 | laminin, beta 3 | -0.0244291 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0243975 |
| SDCBP | syndecan binding protein (syntenin) | -0.0243403 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0238137 |
