| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pravastatin (sodium)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VMP1 | vacuole membrane protein 1 | 0.170495 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0697371 |
| RPL23 | ribosomal protein L23 | 0.0687031 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0593797 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.058419 |
| CEP250 | centrosomal protein 250kDa | 0.0579052 |
| MCL1 | myeloid cell leukemia 1 | 0.0525505 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0506893 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0481298 |
| SP100 | SP100 nuclear antigen | 0.0474826 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0465516 |
| DTNA | dystrobrevin, alpha | 0.0443455 |
| KIAA1217 | KIAA1217 | 0.0438064 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0431349 |
| PLSCR1 | phospholipid scramblase 1 | 0.0411153 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0402933 |
| INTS6 | integrator complex subunit 6 | 0.039368 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0392984 |
| SET | SET nuclear proto-oncogene | 0.0380237 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0366339 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0357128 |
| PLSCR2 | phospholipid scramblase 2 | 0.0356136 |
| ENAH | enabled homolog (Drosophila) | 0.03521 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0345723 |
| VEGFA | vascular endothelial growth factor A | 0.0345702 |
| MSI2 | musashi RNA-binding protein 2 | 0.0345001 |
| RPL37A | ribosomal protein L37a | 0.0331053 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0330081 |
| RPS17 | ribosomal protein S17 | 0.0320423 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0314776 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.030507 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0303116 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0297575 |
| POTEF | POTE ankyrin domain family, member F | 0.0294455 |
| UBAP1 | ubiquitin associated protein 1 | 0.0291004 |
| RASA2 | RAS p21 protein activator 2 | 0.0290851 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0290113 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0287917 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0279935 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0267613 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0264244 |
| PFDN4 | prefoldin subunit 4 | 0.0264146 |
| VCP | valosin containing protein | 0.025484 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0254737 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0251226 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0249623 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0247649 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0244731 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0244511 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0243075 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0242848 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.024205 |
| MT2A | metallothionein 2A | 0.0241598 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0241379 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0240218 |
| RPS6 | ribosomal protein S6 | 0.024007 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0239684 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0234803 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0233205 |
| RBM25 | RNA binding motif protein 25 | 0.0228677 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0228013 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.022494 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0223371 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0221515 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0220568 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0216369 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0215876 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0215219 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.021391 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0213316 |
| INHBA | inhibin, beta A | 0.0213304 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.020987 |
| RCOR1 | REST corepressor 1 | 0.0208057 |
| VCL | vinculin | 0.0203208 |
| GOLGB1 | golgin B1 | 0.0202141 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0201981 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0200672 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0199341 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0197417 |
| EGR1 | early growth response 1 | 0.0196979 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0195383 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0192666 |
| MED13L | mediator complex subunit 13-like | 0.0192604 |
| HOMER1 | homer scaffolding protein 1 | 0.0192062 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0191325 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0190766 |
| USP53 | ubiquitin specific peptidase 53 | 0.0190692 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0190252 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0188058 |
| SCARB1 | scavenger receptor class B, member 1 | 0.0187626 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0186004 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0185369 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | 0.0182713 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0182294 |
| GSE1 | Gse1 coiled-coil protein | 0.0181462 |
| CCNL1 | cyclin L1 | 0.0180696 |
| TMEM165 | transmembrane protein 165 | 0.0179868 |
| RPS12 | ribosomal protein S12 | 0.0177797 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0177783 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) | 0.0176916 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.206889 |
| ASPH | aspartate beta-hydroxylase | -0.162115 |
| LASP1 | LIM and SH3 protein 1 | -0.112477 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.108372 |
| ACACA | acetyl-CoA carboxylase alpha | -0.106441 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.0919668 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0857578 |
| ACTG1 | actin gamma 1 | -0.0818244 |
| AHNAK | AHNAK nucleoprotein | -0.0734448 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0724433 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0718265 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0682788 |
| CDK12 | cyclin-dependent kinase 12 | -0.067072 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0636011 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0597403 |
| PTMA | prothymosin, alpha | -0.0590644 |
| NCOA6 | nuclear receptor coactivator 6 | -0.0590639 |
| ZNF217 | zinc finger protein 217 | -0.0586879 |
| GRB7 | growth factor receptor-bound protein 7 | -0.0578591 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0574593 |
| CLTC | clathrin, heavy chain (Hc) | -0.0574268 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | -0.0573801 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0570549 |
| TC2N | tandem C2 domains, nuclear | -0.0560026 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0546098 |
| KRT19 | keratin 19, type I | -0.0541092 |
| GDPD1 | glycerophosphodiester phosphodiesterase domain containing 1 | -0.0534367 |
| CCND1 | cyclin D1 | -0.0530365 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.0521685 |
| DUSP4 | dual specificity phosphatase 4 | -0.0484211 |
| NTN4 | netrin 4 | -0.046684 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0444403 |
| MYL12B | myosin, light chain 12B, regulatory | -0.043617 |
| ENO1 | enolase 1, (alpha) | -0.0434681 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0434312 |
| CANX | calnexin | -0.0425001 |
| TAOK3 | TAO kinase 3 | -0.0424363 |
| PGK1 | phosphoglycerate kinase 1 | -0.0414561 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0413725 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0395712 |
| MYOF | myoferlin | -0.0393552 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0385984 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0385616 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.0381684 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0380618 |
| CD164 | CD164 molecule, sialomucin | -0.0379474 |
| CCNI | cyclin I | -0.0377557 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0377537 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.037701 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0376789 |
| RRBP1 | ribosome binding protein 1 | -0.0373703 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0370492 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0367267 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0367248 |
| TMEM123 | transmembrane protein 123 | -0.036581 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0363266 |
| FADS2 | fatty acid desaturase 2 | -0.0362757 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0362075 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0352044 |
| MAP4 | microtubule-associated protein 4 | -0.0347558 |
| VAV3 | vav 3 guanine nucleotide exchange factor | -0.0345217 |
| GATA3 | GATA binding protein 3 | -0.0344527 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0342697 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0341321 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0339693 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0333785 |
| MYO6 | myosin VI | -0.033129 |
| TMSB4X | thymosin beta 4, X-linked | -0.0330848 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0324565 |
| YPEL2 | yippee-like 2 (Drosophila) | -0.0316414 |
| LOC112694756 | uncharaterized LOC112694756 | -0.031128 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0309438 |
| TMC5 | transmembrane channel-like 5 | -0.0307875 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0307856 |
| DST | dystonin | -0.0306011 |
| KRT8 | keratin 8, type II | -0.0302047 |
| SMYD3 | SET and MYND domain containing 3 | -0.0300876 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0298528 |
| RESF1 | retroelement silencing factor 1 | -0.0296532 |
| ZNF652 | zinc finger protein 652 | -0.0296433 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0294944 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0292157 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0292116 |
| PTK2 | protein tyrosine kinase 2 | -0.02889 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0287802 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0286607 |
| NF1 | neurofibromin 1 | -0.0285828 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0282804 |
| TXNRD1 | thioredoxin reductase 1 | -0.0282014 |
| GRHL2 | grainyhead-like 2 (Drosophila) | -0.0280512 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.0279793 |
| KRT18 | keratin 18, type I | -0.0278512 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0278375 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0276906 |
| WWC1 | WW and C2 domain containing 1 | -0.0276865 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0275022 |
| SIDT1 | SID1 transmembrane family, member 1 | -0.0269401 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0269379 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0265291 |
| RPL8 | ribosomal protein L8 | -0.0263652 |
