| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pravastatin (sodium)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.139941 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.123503 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0990375 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0855891 |
| NEBL | nebulette | 0.0809743 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0799905 |
| NGLY1 | N-glycanase 1 | 0.0699712 |
| RPS8 | ribosomal protein S8 | 0.065503 |
| ATP11A | ATPase, class VI, type 11A | 0.0609244 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0605069 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.060131 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0575821 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.054323 |
| RPL18 | ribosomal protein L18 | 0.0530766 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0517158 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0512937 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0485102 |
| FAT1 | FAT atypical cadherin 1 | 0.0464329 |
| VMP1 | vacuole membrane protein 1 | 0.046417 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0440228 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0434544 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0418119 |
| EFNA5 | ephrin-A5 | 0.0405815 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0399662 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.0399626 |
| PGK1 | phosphoglycerate kinase 1 | 0.0389132 |
| RPL37A | ribosomal protein L37a | 0.03796 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0379234 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0377282 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0367927 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0362521 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0362257 |
| ARFGEF3 | ARFGEF family member 3 | 0.035793 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0357925 |
| EMP1 | epithelial membrane protein 1 | 0.0353174 |
| TXNRD1 | thioredoxin reductase 1 | 0.0349259 |
| B2M | beta-2-microglobulin | 0.0346979 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0344825 |
| RACK1 | receptor for activated C kinase 1 | 0.0337963 |
| CANX | calnexin | 0.0335375 |
| ZNF292 | zinc finger protein 292 | 0.0335062 |
| DST | dystonin | 0.033499 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0331928 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.032936 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0322094 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0320329 |
| EPN2 | epsin 2 | 0.0318486 |
| RPS4X | ribosomal protein S4, X-linked | 0.0316245 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0311763 |
| LDHA | lactate dehydrogenase A | 0.0311683 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0310204 |
| LRRC1 | leucine rich repeat containing 1 | 0.0309825 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0309132 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0307519 |
| SMYD3 | SET and MYND domain containing 3 | 0.0292524 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.0292025 |
| RPL26 | ribosomal protein L26 | 0.0289801 |
| RPL32 | ribosomal protein L32 | 0.0288676 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0288652 |
| GPR137B | G protein-coupled receptor 137B | 0.0283638 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0281691 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0279052 |
| ZNF608 | zinc finger protein 608 | 0.0278915 |
| IGF2BP1 | insulin-like growth factor 2 mRNA binding protein 1 | 0.0278715 |
| TMEM41B | transmembrane protein 41B | 0.0270508 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0269984 |
| LRRC58 | leucine rich repeat containing 58 | 0.0269812 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0269805 |
| VIM | vimentin | 0.0269041 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0267728 |
| RPL35 | ribosomal protein L35 | 0.0265183 |
| TMEM123 | transmembrane protein 123 | 0.0265083 |
| NUP58 | nucleoporin 58 | 0.0263584 |
| FMNL2 | formin-like 2 | 0.0262413 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0261528 |
| KCNH7 | potassium channel, voltage gated eag related subfamily H, member 7 | 0.026085 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0259861 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0257632 |
| ATRN | attractin | 0.0257455 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.02566 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0254617 |
| RPS6 | ribosomal protein S6 | 0.0254289 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0252554 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0251821 |
| YBX1 | Y box binding protein 1 | 0.0248258 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.024491 |
| RBM25 | RNA binding motif protein 25 | 0.0244098 |
| YEATS2 | YEATS domain containing 2 | 0.0242647 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0241235 |
| TMSB10 | thymosin beta 10 | 0.0241163 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0239298 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0236742 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0227339 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0223707 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.0223508 |
| RLF | rearranged L-myc fusion | 0.0221904 |
| ETNK1 | ethanolamine kinase 1 | 0.0221763 |
| ZNF33A | zinc finger protein 33A | 0.0218528 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.0216867 |
| NPR2 | natriuretic peptide receptor 2 | 0.021675 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.135825 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0880745 |
| RAD51B | RAD51 paralog B | -0.0746318 |
| COL5A2 | collagen, type V, alpha 2 | -0.0707446 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0706565 |
| NFIA | nuclear factor I/A | -0.0656089 |
| RIGI | RNA sensor RIG-I | -0.0641382 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0628357 |
| PTK2 | protein tyrosine kinase 2 | -0.0618203 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0608499 |
| JMJD1C | jumonji domain containing 1C | -0.0594821 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0584049 |
| RPS2 | ribosomal protein S2 | -0.0583917 |
| ACTG1 | actin gamma 1 | -0.0570681 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0518732 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0515232 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0485086 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0482322 |
| TOX | thymocyte selection-associated high mobility group box | -0.0477581 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0463168 |
| USP34 | ubiquitin specific peptidase 34 | -0.0453008 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0452068 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | -0.0445345 |
| CADM2 | cell adhesion molecule 2 | -0.0436321 |
| RBM39 | RNA binding motif protein 39 | -0.0434045 |
| CENPF | centromere protein F, 350/400kDa | -0.043272 |
| INTS6 | integrator complex subunit 6 | -0.0429665 |
| GLG1 | golgi glycoprotein 1 | -0.0428391 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0421985 |
| VCL | vinculin | -0.0420641 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0406764 |
| BNC2 | basonuclin 2 | -0.0401515 |
| ATP9A | ATPase, class II, type 9A | -0.040121 |
| TCF12 | transcription factor 12 | -0.0399338 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0394633 |
| RPL38 | ribosomal protein L38 | -0.0391201 |
| RCC1 | regulator of chromosome condensation 1 | -0.0386407 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0383469 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0383217 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0373979 |
| FHIT | fragile histidine triad | -0.0369474 |
| EGR1 | early growth response 1 | -0.0368223 |
| FTL | ferritin, light polypeptide | -0.0366168 |
| MCL1 | myeloid cell leukemia 1 | -0.0364072 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0361013 |
| SNX14 | sorting nexin 14 | -0.0359459 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0356552 |
| MIPOL1 | mirror-image polydactyly 1 | -0.0355965 |
| FAM193A | family with sequence similarity 193, member A | -0.0352848 |
| PTMA | prothymosin, alpha | -0.0352575 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0351901 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0348316 |
| FUS | FUS RNA binding protein | -0.034704 |
| RPS15 | ribosomal protein S15 | -0.0345625 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.034397 |
| RPS21 | ribosomal protein S21 | -0.0340869 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0336596 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0336576 |
| BRD2 | bromodomain containing 2 | -0.0335809 |
| UBAP2 | ubiquitin associated protein 2 | -0.033446 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0333792 |
| MKI67 | marker of proliferation Ki-67 | -0.0333774 |
| POTEF | POTE ankyrin domain family, member F | -0.0323902 |
| PMP22 | peripheral myelin protein 22 | -0.0322887 |
| ZNF609 | zinc finger protein 609 | -0.0322597 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0316083 |
| CENPE | centromere protein E, 312kDa | -0.0315555 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0314434 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.031439 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0311501 |
| ZNF638 | zinc finger protein 638 | -0.0310365 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0309575 |
| GPATCH8 | G patch domain containing 8 | -0.0306796 |
| RAB10 | RAB10, member RAS oncogene family | -0.0305916 |
| HMGB1 | high mobility group box 1 | -0.030468 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0302021 |
| HSPE1 | heat shock 10kDa protein 1 | -0.0300979 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0299697 |
| FRYL | FRY-like | -0.0299455 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0298252 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.029799 |
| PHF21A | PHD finger protein 21A | -0.0296139 |
| DGKH | diacylglycerol kinase, eta | -0.0293872 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0292092 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.0289487 |
| HMGB2 | high mobility group box 2 | -0.0288131 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0283941 |
| HELZ | helicase with zinc finger | -0.0283718 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0282436 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0282422 |
| RPL21 | ribosomal protein L21 | -0.0273386 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.027234 |
| TNRC18 | trinucleotide repeat containing 18 | -0.027128 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0270798 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited | -0.0270423 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0268929 |
| MT2A | metallothionein 2A | -0.0265999 |
| WDR1 | WD repeat domain 1 | -0.0264365 |
| MATR3 | matrin 3 | -0.0263023 |
| HELLS | helicase, lymphoid-specific | -0.0262069 |
