| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pravastatin (sodium)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD109 | CD109 molecule | 0.125895 |
| RNF145 | ring finger protein 145 | 0.0739716 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0697665 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0676139 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.063361 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0615061 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0596352 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0581706 |
| DST | dystonin | 0.056608 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.056553 |
| COPA | coatomer protein complex, subunit alpha | 0.0520183 |
| CENPF | centromere protein F, 350/400kDa | 0.0515241 |
| DCT | dopachrome tautomerase | 0.0505247 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0501331 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.049652 |
| VIM | vimentin | 0.0488952 |
| CDK19 | cyclin-dependent kinase 19 | 0.0487969 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0486343 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.046738 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0460045 |
| OGA | O-GlcNAcase | 0.0454454 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0448421 |
| RPS12 | ribosomal protein S12 | 0.0420542 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0418524 |
| NAV2 | neuron navigator 2 | 0.0417248 |
| FOXJ3 | forkhead box J3 | 0.0411663 |
| NBAS | neuroblastoma amplified sequence | 0.0404694 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0395149 |
| GOLGA4 | golgin A4 | 0.0388718 |
| TPR | translocated promoter region, nuclear basket protein | 0.0371307 |
| CTTNBP2 | cortactin binding protein 2 | 0.0358924 |
| BBX | bobby sox homolog (Drosophila) | 0.0357178 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0351972 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0351014 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0342733 |
| FBXO7 | F-box protein 7 | 0.0342394 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0340993 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.03405 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0333987 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.0328146 |
| MYO10 | myosin X | 0.0324977 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0321615 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0320504 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0315369 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0304131 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0303606 |
| FMNL2 | formin-like 2 | 0.0303097 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0301642 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0300983 |
| VMP1 | vacuole membrane protein 1 | 0.0300875 |
| ANXA5 | annexin A5 | 0.0299592 |
| GSK3B | glycogen synthase kinase 3 beta | 0.029935 |
| RPS8 | ribosomal protein S8 | 0.0292535 |
| ZNF292 | zinc finger protein 292 | 0.0291264 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0289963 |
| WDR43 | WD repeat domain 43 | 0.0288744 |
| ASPH | aspartate beta-hydroxylase | 0.028698 |
| RBM25 | RNA binding motif protein 25 | 0.0282096 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0279472 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0278903 |
| GTF2I | general transcription factor IIi | 0.0276969 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.02744 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0271694 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0271582 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0269453 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.0267073 |
| AFDN | afadin, adherens junction formation factor | 0.0264554 |
| RPS3 | ribosomal protein S3 | 0.026418 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0261122 |
| RNF24 | ring finger protein 24 | 0.0260477 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.026046 |
| SRPK2 | SRSF protein kinase 2 | 0.0255991 |
| CALD1 | caldesmon 1 | 0.0254714 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0253955 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0253595 |
| PYGB | phosphorylase, glycogen; brain | 0.0252821 |
| MRTFA | myocardin related transcription factor A | 0.0251494 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0246959 |
| FBXO42 | F-box protein 42 | 0.0245795 |
| RAI1 | retinoic acid induced 1 | 0.0245196 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0243136 |
| EXOC4 | exocyst complex component 4 | 0.0243114 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0242188 |
| NUP58 | nucleoporin 58 | 0.0239906 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0239684 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.023867 |
| PTK2 | protein tyrosine kinase 2 | 0.0238167 |
| FOSL1 | FOS-like antigen 1 | 0.0237844 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0236789 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0236615 |
| S100A6 | S100 calcium binding protein A6 | 0.0235905 |
| DICER1 | dicer 1, ribonuclease type III | 0.0234301 |
| POM121 | POM121 transmembrane nucleoporin | 0.0232793 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.02286 |
| CDC27 | cell division cycle 27 | 0.0228485 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.022848 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0227445 |
| RPS2 | ribosomal protein S2 | 0.022665 |
| MKRN1 | makorin ring finger protein 1 | 0.0225097 |
| POLR3G | polymerase (RNA) III (DNA directed) polypeptide G (32kD) | 0.0224544 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.534243 |
| FN1 | fibronectin 1 | -0.255822 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.177021 |
| EGR1 | early growth response 1 | -0.105398 |
| ACTG1 | actin gamma 1 | -0.101599 |
| NDRG1 | N-myc downstream regulated 1 | -0.0943974 |
| FMN1 | formin 1 | -0.0784287 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0708559 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0679849 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0648217 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0646247 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0615859 |
| NLGN1 | neuroligin 1 | -0.0602476 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0591686 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0585478 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0573788 |
| GPC6 | glypican 6 | -0.0540091 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0537795 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0536895 |
| MT2A | metallothionein 2A | -0.0528845 |
| VCL | vinculin | -0.0528519 |
| TMSB10 | thymosin beta 10 | -0.0486829 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0482496 |
| A2M | alpha-2-macroglobulin | -0.0478845 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0456058 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0429851 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.0400947 |
| PAX3 | paired box 3 | -0.0377866 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0376557 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0365887 |
| CTSD | cathepsin D | -0.0361743 |
| IER3 | immediate early response 3 | -0.0352306 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0346519 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0342752 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0338664 |
| TLE4 | transducin-like enhancer of split 4 | -0.0332977 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | -0.0326267 |
| AHNAK | AHNAK nucleoprotein | -0.032556 |
| TNNC1 | troponin C type 1 (slow) | -0.0325519 |
| FTL | ferritin, light polypeptide | -0.0321782 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0318232 |
| PTCHD4 | patched domain containing 4 | -0.0315711 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0306835 |
| IGF2 | insulin-like growth factor 2 | -0.0304312 |
| RYBP | RING1 and YY1 binding protein | -0.0297884 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0295572 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0287842 |
| RPL19 | ribosomal protein L19 | -0.0286219 |
| CLIC4 | chloride intracellular channel 4 | -0.028043 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0277099 |
| RHEB | Ras homolog enriched in brain | -0.0275661 |
| FUS | FUS RNA binding protein | -0.0258692 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0256624 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0255977 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0254054 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0251452 |
| RPS24 | ribosomal protein S24 | -0.0250856 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0247368 |
| UBC | ubiquitin C | -0.0246422 |
| POTEF | POTE ankyrin domain family, member F | -0.0243422 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0243088 |
| CALR | calreticulin | -0.0243009 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0238632 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0236117 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0233973 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0232639 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0232196 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0229912 |
| MYO1E | myosin IE | -0.0229667 |
| LRRC23 | leucine rich repeat containing 23 | -0.0227307 |
| ATF6 | activating transcription factor 6 | -0.0226052 |
| ARF1 | ADP-ribosylation factor 1 | -0.0224555 |
| GPHN | gephyrin | -0.022443 |
| OSMR | oncostatin M receptor | -0.0221475 |
| INTS6 | integrator complex subunit 6 | -0.0221333 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0219003 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0216524 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0212518 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0211879 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0210162 |
| NAV3 | neuron navigator 3 | -0.0208561 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0206173 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0204043 |
| JUN | jun proto-oncogene | -0.0202534 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0202377 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0202006 |
| DMXL1 | Dmx-like 1 | -0.0201975 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0201914 |
| GTF2B | general transcription factor IIB | -0.0199988 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0199606 |
| NPR2 | natriuretic peptide receptor 2 | -0.0199472 |
| EMP1 | epithelial membrane protein 1 | -0.0198643 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | -0.019737 |
| NEGR1 | neuronal growth regulator 1 | -0.0196855 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0195492 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.019493 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0192534 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.0191371 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0191204 |
| TMEM123 | transmembrane protein 123 | -0.0190415 |
