| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pravastatin (sodium)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.196765 |
| FAM13A | family with sequence similarity 13, member A | 0.134552 |
| VIM | vimentin | 0.112174 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.107817 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.100973 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0932261 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.079463 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0786357 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0770477 |
| CCNY | cyclin Y | 0.0755289 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0747443 |
| PTMA | prothymosin, alpha | 0.0723456 |
| TOP1 | topoisomerase (DNA) I | 0.0690905 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0672058 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0651887 |
| OGA | O-GlcNAcase | 0.0646061 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0631383 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0588845 |
| EREG | epiregulin | 0.0565386 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0548459 |
| FLNB | filamin B, beta | 0.0546757 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0543815 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0541297 |
| RPS8 | ribosomal protein S8 | 0.0541001 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0519937 |
| MEF2A | myocyte enhancer factor 2A | 0.0515509 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0498067 |
| FOSL1 | FOS-like antigen 1 | 0.0489716 |
| RPL23 | ribosomal protein L23 | 0.0476309 |
| LAMB3 | laminin, beta 3 | 0.0461975 |
| S100A6 | S100 calcium binding protein A6 | 0.0454823 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0443124 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0433932 |
| HDGF | hepatoma-derived growth factor | 0.042588 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0413654 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.040862 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0395672 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0391215 |
| ZNF292 | zinc finger protein 292 | 0.0387763 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0354919 |
| NUP58 | nucleoporin 58 | 0.034853 |
| ATP13A3 | ATPase type 13A3 | 0.0348058 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0346573 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0344713 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0344503 |
| RPS3 | ribosomal protein S3 | 0.0339686 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0338904 |
| PLAU | plasminogen activator, urokinase | 0.0336141 |
| G0S2 | G0/G1 switch 2 | 0.0332234 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0332008 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0331999 |
| PCBP2 | poly(rC) binding protein 2 | 0.0326922 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0318907 |
| RAI1 | retinoic acid induced 1 | 0.0318328 |
| RNF149 | ring finger protein 149 | 0.0308032 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0301033 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0300044 |
| RPS12 | ribosomal protein S12 | 0.029643 |
| CASC3 | cancer susceptibility candidate 3 | 0.0289525 |
| RPS17 | ribosomal protein S17 | 0.0288319 |
| CD47 | CD47 molecule | 0.028613 |
| RACK1 | receptor for activated C kinase 1 | 0.0284658 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0282422 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0280438 |
| SQSTM1 | sequestosome 1 | 0.0278056 |
| USP3 | ubiquitin specific peptidase 3 | 0.0274435 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.027226 |
| PROSER2 | proline and serine rich 2 | 0.0272064 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0267237 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.026602 |
| FNBP1L | formin binding protein 1-like | 0.0265456 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0265209 |
| YBX1 | Y box binding protein 1 | 0.0265208 |
| HMGA2 | high mobility group AT-hook 2 | 0.0260431 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0259844 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0257294 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0256293 |
| QKI | QKI, KH domain containing, RNA binding | 0.0254434 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0251918 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0251558 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0249518 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0248989 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0244808 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.0242857 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0242681 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0242528 |
| SLMAP | sarcolemma associated protein | 0.0241774 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.023571 |
| ZFP36 | ZFP36 ring finger protein | 0.0235622 |
| SERINC1 | serine incorporator 1 | 0.0235435 |
| FA2H | fatty acid 2-hydroxylase | 0.0231853 |
| PATL1 | protein associated with topoisomerase II homolog 1 (yeast) | 0.0231273 |
| RPL37A | ribosomal protein L37a | 0.0231231 |
| RBM25 | RNA binding motif protein 25 | 0.022492 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0224591 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0223535 |
| RPS26 | ribosomal protein S26 | 0.0223276 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0222314 |
| CENPF | centromere protein F, 350/400kDa | 0.0220245 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0219992 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.328466 |
| NDRG1 | N-myc downstream regulated 1 | -0.134431 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.129882 |
| HLA-B | major histocompatibility complex, class I, B | -0.0944974 |
| DSG2 | desmoglein 2 | -0.0783585 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0750827 |
| KRT19 | keratin 19, type I | -0.0733944 |
| MYO1E | myosin IE | -0.0702308 |
| EFNA5 | ephrin-A5 | -0.0690669 |
| APOL1 | apolipoprotein L, 1 | -0.0688339 |
| EGR1 | early growth response 1 | -0.0675284 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0659249 |
| RNF213 | ring finger protein 213 | -0.0653835 |
| CP | ceruloplasmin (ferroxidase) | -0.0650063 |
| ACTG1 | actin gamma 1 | -0.0646633 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0645356 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0628881 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0610886 |
| TXNIP | thioredoxin interacting protein | -0.0590318 |
| UBC | ubiquitin C | -0.0576409 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0539875 |
| OSMR | oncostatin M receptor | -0.0537087 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0534816 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0533592 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0519322 |
| BICC1 | BicC family RNA binding protein 1 | -0.0514374 |
| LMO7 | LIM domain 7 | -0.0510735 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0495895 |
| FTL | ferritin, light polypeptide | -0.0492627 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0484297 |
| HMGA1 | high mobility group AT-hook 1 | -0.0478117 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0469302 |
| DST | dystonin | -0.0464399 |
| MUC4 | mucin 4, cell surface associated | -0.0459046 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0458877 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0455498 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0451074 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0440018 |
| LAMA4 | laminin, alpha 4 | -0.0432117 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0429638 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.042712 |
| MT2A | metallothionein 2A | -0.0425333 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0424522 |
| ERBIN | erbb2 interacting protein | -0.0424334 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.042155 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0419124 |
| CLTC | clathrin, heavy chain (Hc) | -0.0417255 |
| NRP1 | neuropilin 1 | -0.0400761 |
| TJP1 | tight junction protein 1 | -0.0394586 |
| ANXA2 | annexin A2 | -0.039293 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0389277 |
| NABP1 | nucleic acid binding protein 1 | -0.0388777 |
| EMP1 | epithelial membrane protein 1 | -0.0381511 |
| BRD2 | bromodomain containing 2 | -0.0381024 |
| FNIP1 | folliculin interacting protein 1 | -0.0377485 |
| MX1 | MX dynamin-like GTPase 1 | -0.0375269 |
| RRBP1 | ribosome binding protein 1 | -0.037393 |
| USP53 | ubiquitin specific peptidase 53 | -0.0367346 |
| HDLBP | high density lipoprotein binding protein | -0.0362353 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0359644 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0358371 |
| PRKCA | protein kinase C, alpha | -0.0353252 |
| PKM | pyruvate kinase, muscle | -0.0350788 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0349045 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.034465 |
| SGMS2 | sphingomyelin synthase 2 | -0.0342857 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0342465 |
| DUSP5 | dual specificity phosphatase 5 | -0.0341678 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0336685 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.033635 |
| CDK12 | cyclin-dependent kinase 12 | -0.0333395 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.033259 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0331778 |
| RBM47 | RNA binding motif protein 47 | -0.0331433 |
| TMC5 | transmembrane channel-like 5 | -0.0326748 |
| LAMC2 | laminin, gamma 2 | -0.0323514 |
| IL6ST | interleukin 6 signal transducer | -0.0322696 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0320362 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0320274 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0319846 |
| SP100 | SP100 nuclear antigen | -0.0317221 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0313277 |
| FRYL | FRY-like | -0.0313185 |
| FUS | FUS RNA binding protein | -0.0312186 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.0308667 |
| ASPH | aspartate beta-hydroxylase | -0.0308218 |
| FAM3C | family with sequence similarity 3, member C | -0.0307487 |
| EXT1 | exostosin glycosyltransferase 1 | -0.030375 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0302472 |
| CD2AP | CD2-associated protein | -0.0302388 |
| MT1X | metallothionein 1X | -0.0301661 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0300882 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0300063 |
| LCN2 | lipocalin 2 | -0.0299079 |
| GOLGB1 | golgin B1 | -0.0299021 |
| RASAL2 | RAS protein activator like 2 | -0.0297653 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0297213 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0295679 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0292424 |
| MX2 | MX dynamin-like GTPase 2 | -0.0289798 |
