| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pravastatin (sodium)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.25703 |
| VIM | vimentin | 0.11564 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0987833 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0930036 |
| RPL37A | ribosomal protein L37a | 0.0772225 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0697314 |
| CENPF | centromere protein F, 350/400kDa | 0.0649347 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0539615 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0529281 |
| FAM13A | family with sequence similarity 13, member A | 0.0507339 |
| RPS12 | ribosomal protein S12 | 0.0495541 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0470162 |
| NBAS | neuroblastoma amplified sequence | 0.0461792 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0456236 |
| PTMA | prothymosin, alpha | 0.045523 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0450064 |
| ASPH | aspartate beta-hydroxylase | 0.0433075 |
| RPL23 | ribosomal protein L23 | 0.0383885 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0362362 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0345121 |
| RPS6 | ribosomal protein S6 | 0.0338875 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0337766 |
| LPIN1 | lipin 1 | 0.033367 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.032678 |
| RAD51B | RAD51 paralog B | 0.0322242 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0321944 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0318446 |
| DST | dystonin | 0.03158 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0309827 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0306763 |
| DACH2 | dachshund family transcription factor 2 | 0.0304743 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0300399 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0290347 |
| RPL26 | ribosomal protein L26 | 0.0286773 |
| DIAPH3 | diaphanous-related formin 3 | 0.0284025 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.0283971 |
| RPS17 | ribosomal protein S17 | 0.0277924 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0277589 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0273931 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0273528 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0272304 |
| VPS35 | vacuolar protein sorting 35 homolog (S. cerevisiae) | 0.0271242 |
| RBM25 | RNA binding motif protein 25 | 0.0265948 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0265642 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0264065 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0263486 |
| CBX3 | chromobox homolog 3 | 0.0262833 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0254967 |
| RPS8 | ribosomal protein S8 | 0.0253754 |
| COL3A1 | collagen, type III, alpha 1 | 0.0253558 |
| RPL5 | ribosomal protein L5 | 0.0249825 |
| SEPTIN9 | septin 9 | 0.0248307 |
| SET | SET nuclear proto-oncogene | 0.0247562 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0245735 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0245093 |
| RPL35A | ribosomal protein L35a | 0.0244722 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0239917 |
| NKTR | natural killer cell triggering receptor | 0.0239323 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0238336 |
| CDH13 | cadherin 13 | 0.0237191 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0236979 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0236631 |
| ACBD6 | acyl-CoA binding domain containing 6 | 0.0236294 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0236282 |
| HDAC8 | histone deacetylase 8 | 0.0235675 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0235187 |
| TPR | translocated promoter region, nuclear basket protein | 0.0234479 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0234425 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0232078 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0231746 |
| CD44 | CD44 molecule (Indian blood group) | 0.0231228 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0230656 |
| ANO6 | anoctamin 6 | 0.0229053 |
| MKI67 | marker of proliferation Ki-67 | 0.022598 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0225653 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.022547 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.022439 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0224277 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0222453 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0221971 |
| HDGF | hepatoma-derived growth factor | 0.0219588 |
| TRIB2 | tribbles pseudokinase 2 | 0.0219375 |
| XPO1 | exportin 1 | 0.0217833 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0217634 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0217615 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0216869 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0216477 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0214672 |
| ZNF148 | zinc finger protein 148 | 0.0213974 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0213058 |
| ZNF292 | zinc finger protein 292 | 0.0212744 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0212265 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0211276 |
| PNN | pinin, desmosome associated protein | 0.0208823 |
| PKM | pyruvate kinase, muscle | 0.0205709 |
| RPS3 | ribosomal protein S3 | 0.0205481 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.0204066 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0202848 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0202489 |
| NPAS3 | neuronal PAS domain protein 3 | 0.020242 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.551951 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.220949 |
| VCL | vinculin | -0.0863913 |
| SYT1 | synaptotagmin I | -0.0725981 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0679877 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.062356 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0618729 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0592605 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.057912 |
| FMN1 | formin 1 | -0.0523085 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0506621 |
| ACTG1 | actin gamma 1 | -0.0493274 |
| SIK2 | salt-inducible kinase 2 | -0.0472289 |
| VMP1 | vacuole membrane protein 1 | -0.0466142 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0440511 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0429153 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0413575 |
| EGR1 | early growth response 1 | -0.0398856 |
| GLCCI1 | glucocorticoid induced 1 | -0.0398843 |
| FNDC3A | fibronectin type III domain containing 3A | -0.038948 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0384038 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0374576 |
| BPTF | bromodomain PHD finger transcription factor | -0.0372094 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0356264 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0348765 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0330024 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0323738 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0304486 |
| STK38L | serine/threonine kinase 38 like | -0.030219 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | -0.0301775 |
| IER3 | immediate early response 3 | -0.0298969 |
| MED13 | mediator complex subunit 13 | -0.0296714 |
| FNBP4 | formin binding protein 4 | -0.0295081 |
| GLG1 | golgi glycoprotein 1 | -0.0294515 |
| RPS15 | ribosomal protein S15 | -0.0292224 |
| NDRG1 | N-myc downstream regulated 1 | -0.0290235 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0289838 |
| SON | SON DNA binding protein | -0.0288572 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0287466 |
| SSH2 | slingshot protein phosphatase 2 | -0.0285111 |
| GAB2 | GRB2-associated binding protein 2 | -0.0279288 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0273285 |
| FERMT2 | fermitin family member 2 | -0.0272596 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0269226 |
| TAOK1 | TAO kinase 1 | -0.0266135 |
| THBS1 | thrombospondin 1 | -0.0265728 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.0265695 |
| HDLBP | high density lipoprotein binding protein | -0.026223 |
| TET2 | tet methylcytosine dioxygenase 2 | -0.0261696 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0259353 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0254134 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.025277 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0252071 |
| RCOR1 | REST corepressor 1 | -0.0250734 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.024843 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | -0.0246622 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.024571 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0243411 |
| CSNK1G1 | casein kinase 1, gamma 1 | -0.0239441 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0237636 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0237372 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0237123 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0235409 |
| HELZ | helicase with zinc finger | -0.0234722 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0233604 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0229831 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0229278 |
| CANX | calnexin | -0.0227782 |
| H3-3B | H3.3 histone B | -0.0227125 |
| RAB1A | RAB1A, member RAS oncogene family | -0.022552 |
| ANXA2 | annexin A2 | -0.0223709 |
| PLPP1 | phospholipid phosphatase 1 | -0.022335 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0223322 |
| RYBP | RING1 and YY1 binding protein | -0.0223242 |
| GNAS | GNAS complex locus | -0.0222462 |
| TCF12 | transcription factor 12 | -0.0220338 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0218412 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | -0.0217865 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0216443 |
| FOXO3 | forkhead box O3 | -0.0216225 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0215719 |
| GPATCH8 | G patch domain containing 8 | -0.0215366 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0214556 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0212848 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0211632 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0208883 |
| FHL2 | four and a half LIM domains 2 | -0.0207545 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.020711 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0206513 |
| FOXO1 | forkhead box O1 | -0.0206286 |
| ITPKB | inositol-trisphosphate 3-kinase B | -0.0205634 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.020474 |
| USP36 | ubiquitin specific peptidase 36 | -0.0204271 |
| PELO | pelota homolog (Drosophila) | -0.0200751 |
| MBTD1 | mbt domain containing 1 | -0.0198944 |
| AMOTL1 | angiomotin like 1 | -0.019878 |
| RNASEH2A | ribonuclease H2, subunit A | -0.0198122 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0197663 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0197541 |
| R3HDM2 | R3H domain containing 2 | -0.0194359 |
