| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pravastatin (sodium)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.195173 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.108085 |
| INTS6 | integrator complex subunit 6 | 0.104879 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.07646 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0705033 |
| RPS6 | ribosomal protein S6 | 0.0689333 |
| SMAD3 | SMAD family member 3 | 0.0628321 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0604888 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0577662 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0571478 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.05238 |
| PLSCR2 | phospholipid scramblase 2 | 0.0522768 |
| ASPH | aspartate beta-hydroxylase | 0.0464501 |
| RNF149 | ring finger protein 149 | 0.0461474 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0452556 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0445275 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0419494 |
| OGA | O-GlcNAcase | 0.0412968 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0408292 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0395591 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0389669 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0382847 |
| RPLP1 | ribosomal protein, large, P1 | 0.0374338 |
| AHNAK | AHNAK nucleoprotein | 0.0362654 |
| RPS8 | ribosomal protein S8 | 0.0346332 |
| PRELID2 | PRELI domain containing 2 | 0.034236 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0337612 |
| RPL37A | ribosomal protein L37a | 0.0337394 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0335441 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0329401 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0329226 |
| RPL23 | ribosomal protein L23 | 0.0326617 |
| CALR | calreticulin | 0.032238 |
| AHI1 | Abelson helper integration site 1 | 0.0314789 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0308232 |
| GOLGA4 | golgin A4 | 0.0307409 |
| RPS12 | ribosomal protein S12 | 0.0307249 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0303314 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.030003 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0296358 |
| RPL35A | ribosomal protein L35a | 0.0290962 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0290738 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0289075 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.028733 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0277776 |
| TBPL1 | TBP-like 1 | 0.0274305 |
| TXNIP | thioredoxin interacting protein | 0.0273397 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0271357 |
| NDRG1 | N-myc downstream regulated 1 | 0.0269478 |
| RPL26 | ribosomal protein L26 | 0.0265689 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0265084 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0261494 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0260222 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0257559 |
| RPS3 | ribosomal protein S3 | 0.025721 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0256176 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0254747 |
| ZNF638 | zinc finger protein 638 | 0.0254654 |
| PRRC2C | proline-rich coiled-coil 2C | 0.025343 |
| SBF2 | SET binding factor 2 | 0.0250298 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0249875 |
| ARRDC3 | arrestin domain containing 3 | 0.0249703 |
| NUCB2 | nucleobindin 2 | 0.0245061 |
| RPL12 | ribosomal protein L12 | 0.0242668 |
| RPS19 | ribosomal protein S19 | 0.0241613 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0240991 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0236565 |
| USP3 | ubiquitin specific peptidase 3 | 0.0236485 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0230885 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0225947 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0223984 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0222664 |
| ENO1 | enolase 1, (alpha) | 0.0222607 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0220287 |
| SSR1 | signal sequence receptor, alpha | 0.021767 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0217609 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0217212 |
| MLPH | melanophilin | 0.0216946 |
| RPL7 | ribosomal protein L7 | 0.0214487 |
| PTEN | phosphatase and tensin homolog | 0.0213045 |
| EREG | epiregulin | 0.0212086 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0207966 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0205405 |
| HBS1L | HBS1-like translational GTPase | 0.020516 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0205076 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0204017 |
| XPO1 | exportin 1 | 0.0202551 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0202501 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0200898 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0200338 |
| HYOU1 | hypoxia up-regulated 1 | 0.0199636 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0197788 |
| RNF145 | ring finger protein 145 | 0.0197653 |
| RSF1 | remodeling and spacing factor 1 | 0.0196831 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0195168 |
| RPS17 | ribosomal protein S17 | 0.019511 |
| RPL18 | ribosomal protein L18 | 0.0194459 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0189194 |
| FANCI | Fanconi anemia, complementation group I | 0.0188701 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0188249 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.184919 |
| EGR1 | early growth response 1 | -0.120856 |
| LYZ | lysozyme | -0.115648 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.114301 |
| LMO7 | LIM domain 7 | -0.104003 |
| MX1 | MX dynamin-like GTPase 1 | -0.0993605 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0965002 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0951827 |
| SPATA13 | spermatogenesis associated 13 | -0.09293 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.090224 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0835527 |
| RIGI | RNA sensor RIG-I | -0.0800381 |
| RNF213 | ring finger protein 213 | -0.077635 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0763022 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0762917 |
| MX2 | MX dynamin-like GTPase 2 | -0.0753507 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0734437 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0722588 |
| TMC5 | transmembrane channel-like 5 | -0.0673179 |
| JUN | jun proto-oncogene | -0.0646834 |
| PLSCR1 | phospholipid scramblase 1 | -0.0637158 |
| EZR | ezrin | -0.063629 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0633532 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0629314 |
| EXT1 | exostosin glycosyltransferase 1 | -0.062632 |
| ITGA6 | integrin, alpha 6 | -0.0626241 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0606809 |
| XAF1 | XIAP associated factor 1 | -0.05977 |
| HLA-B | major histocompatibility complex, class I, B | -0.0581976 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0576345 |
| SP100 | SP100 nuclear antigen | -0.0569584 |
| EPHB2 | EPH receptor B2 | -0.0567743 |
| MYO1E | myosin IE | -0.052242 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0505508 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0504226 |
| SQSTM1 | sequestosome 1 | -0.0497622 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0490049 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0478475 |
| NCKAP5 | NCK-associated protein 5 | -0.0472741 |
| PMP22 | peripheral myelin protein 22 | -0.0458058 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0457217 |
| IRF1 | interferon regulatory factor 1 | -0.0448985 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0440903 |
| ERBIN | erbb2 interacting protein | -0.0437343 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.043131 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0430184 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0420729 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0419852 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0410303 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0400479 |
| ETV6 | ets variant 6 | -0.0398688 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0388935 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0388349 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.0384778 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | -0.0382035 |
| MUC13 | mucin 13, cell surface associated | -0.0375547 |
| MUC20 | mucin 20, cell surface associated | -0.0373306 |
| FMN1 | formin 1 | -0.0365967 |
| CCNL1 | cyclin L1 | -0.0362231 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0360531 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0356857 |
| SLC38A1 | solute carrier family 38, member 1 | -0.034995 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0346698 |
| LAP3 | leucine aminopeptidase 3 | -0.0335149 |
| TMEM62 | transmembrane protein 62 | -0.0332641 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0327291 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0326463 |
| MECOM | MDS1 and EVI1 complex locus | -0.0323219 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | -0.0322938 |
| LCN2 | lipocalin 2 | -0.032288 |
| ANXA2 | annexin A2 | -0.0319346 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0315169 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0314141 |
| SDCBP2 | syndecan binding protein (syntenin) 2 | -0.0313366 |
| ACTG1 | actin gamma 1 | -0.0307689 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0304635 |
| APOL6 | apolipoprotein L, 6 | -0.0304555 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0304088 |
| HLA-E | major histocompatibility complex, class I, E | -0.0301626 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0298438 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0298043 |
| NPSR1 | neuropeptide S receptor 1 | -0.0292424 |
| ATP10B | ATPase, class V, type 10B | -0.0288607 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0285897 |
| MCU | mitochondrial calcium uniporter | -0.0285309 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0273541 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0268536 |
| TRIM2 | tripartite motif containing 2 | -0.0267947 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0267282 |
| RBM47 | RNA binding motif protein 47 | -0.0263742 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.026198 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0259493 |
| OCLN | occludin | -0.0256155 |
| TC2N | tandem C2 domains, nuclear | -0.0254732 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0253434 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0247008 |
| KLF6 | Kruppel-like factor 6 | -0.0245808 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.0245613 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0243831 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0238917 |
