| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pravastatin (sodium)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.170538 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.115919 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.105673 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0845808 |
| RPS6 | ribosomal protein S6 | 0.0797517 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0791762 |
| EGFR | epidermal growth factor receptor | 0.0763972 |
| STC1 | stanniocalcin 1 | 0.0761762 |
| VIM | vimentin | 0.0737603 |
| FAM13A | family with sequence similarity 13, member A | 0.0701902 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0677497 |
| RPS8 | ribosomal protein S8 | 0.0659854 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0653886 |
| CALD1 | caldesmon 1 | 0.0600219 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0576678 |
| SBF2 | SET binding factor 2 | 0.0573985 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0572204 |
| ATP13A3 | ATPase type 13A3 | 0.0556648 |
| RPL37A | ribosomal protein L37a | 0.0552388 |
| CADM1 | cell adhesion molecule 1 | 0.0506791 |
| RPL9 | ribosomal protein L9 | 0.0501519 |
| SMAD3 | SMAD family member 3 | 0.048849 |
| ZNF292 | zinc finger protein 292 | 0.0474822 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.046113 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0441547 |
| RPS3 | ribosomal protein S3 | 0.043807 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0435627 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0433976 |
| RPS2 | ribosomal protein S2 | 0.0431767 |
| DST | dystonin | 0.0416239 |
| PTMA | prothymosin, alpha | 0.0410821 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0409996 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0375632 |
| TNS3 | tensin 3 | 0.0363125 |
| GOLGB1 | golgin B1 | 0.035951 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0356579 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0356509 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0356057 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0353008 |
| GOLGA4 | golgin A4 | 0.0352159 |
| SETD5 | SET domain containing 5 | 0.0351772 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0345111 |
| RTN4 | reticulon 4 | 0.0343858 |
| RACK1 | receptor for activated C kinase 1 | 0.0343608 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0339059 |
| COG5 | component of oligomeric golgi complex 5 | 0.0338274 |
| RPS12 | ribosomal protein S12 | 0.0329094 |
| SRP54 | signal recognition particle 54kDa | 0.0327169 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.032565 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.032275 |
| VMP1 | vacuole membrane protein 1 | 0.0317797 |
| RPL18 | ribosomal protein L18 | 0.0315782 |
| PCBP2 | poly(rC) binding protein 2 | 0.0312374 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0312046 |
| ZNF841 | zinc finger protein 841 | 0.0311786 |
| NDRG1 | N-myc downstream regulated 1 | 0.0306489 |
| EXOC4 | exocyst complex component 4 | 0.0302496 |
| RPS27A | ribosomal protein S27a | 0.030061 |
| THOC2 | THO complex 2 | 0.030024 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0298118 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0297197 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0296726 |
| MSN | moesin | 0.0292223 |
| FNIP1 | folliculin interacting protein 1 | 0.0291351 |
| NDUFB4 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa | 0.0290316 |
| OGA | O-GlcNAcase | 0.0288319 |
| HDGF | hepatoma-derived growth factor | 0.0285787 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0284859 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0283997 |
| BBX | bobby sox homolog (Drosophila) | 0.0282745 |
| INSIG2 | insulin induced gene 2 | 0.0279465 |
| YEATS2 | YEATS domain containing 2 | 0.0277983 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0277843 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0277286 |
| GLIS3 | GLIS family zinc finger 3 | 0.0276617 |
| PRELID2 | PRELI domain containing 2 | 0.0276527 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0276334 |
| TPM3 | tropomyosin 3 | 0.0272428 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0271778 |
| FOXJ3 | forkhead box J3 | 0.0269198 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0268598 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0266447 |
| TGFB1 | transforming growth factor, beta 1 | 0.0264856 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0262985 |
| RASA2 | RAS p21 protein activator 2 | 0.0261303 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0260261 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.026014 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0256461 |
| NUCB2 | nucleobindin 2 | 0.0255237 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0254348 |
| TRAM1 | translocation associated membrane protein 1 | 0.0254306 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.025418 |
| GOLGA2 | golgin A2 | 0.0253811 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0253046 |
| MYOF | myoferlin | 0.025103 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0249784 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.024891 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0248226 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0246671 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0245235 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.450887 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.21707 |
| FTL | ferritin, light polypeptide | -0.158635 |
| FN1 | fibronectin 1 | -0.135111 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0969469 |
| EGR1 | early growth response 1 | -0.0745814 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0719163 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0717993 |
| HLA-B | major histocompatibility complex, class I, B | -0.0686217 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0658425 |
| LOX | lysyl oxidase | -0.0630554 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0582319 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0573025 |
| TMSB10 | thymosin beta 10 | -0.0535219 |
| VDAC1 | voltage-dependent anion channel 1 | -0.050807 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.045641 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0440241 |
| AHNAK | AHNAK nucleoprotein | -0.0357422 |
| ARF1 | ADP-ribosylation factor 1 | -0.0355262 |
| TXNRD1 | thioredoxin reductase 1 | -0.0354467 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.035107 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0341649 |
| IGF2 | insulin-like growth factor 2 | -0.0330873 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0313287 |
| NLGN1 | neuroligin 1 | -0.0309133 |
| MT1X | metallothionein 1X | -0.0304701 |
| ASPH | aspartate beta-hydroxylase | -0.0295881 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0294732 |
| HDLBP | high density lipoprotein binding protein | -0.0288678 |
| CALU | calumenin | -0.0284946 |
| PRSS23 | protease, serine, 23 | -0.0284752 |
| TPTE | transmembrane phosphatase with tensin homology | -0.0280067 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0279939 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0274704 |
| RPLP1 | ribosomal protein, large, P1 | -0.0273688 |
| ENO1 | enolase 1, (alpha) | -0.0273092 |
| RPL34 | ribosomal protein L34 | -0.027294 |
| PXDN | peroxidasin | -0.0272621 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0270729 |
| HLA-C | major histocompatibility complex, class I, C | -0.0266897 |
| PLEC | plectin | -0.0262954 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0261967 |
| RIGI | RNA sensor RIG-I | -0.0254643 |
| AHR | aryl hydrocarbon receptor | -0.0246013 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.024352 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0243016 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0242299 |
| PTK2 | protein tyrosine kinase 2 | -0.0240413 |
| FSTL1 | follistatin-like 1 | -0.023883 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0238454 |
| KYNU | kynureninase | -0.0235697 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0235356 |
| AUTS2 | autism susceptibility candidate 2 | -0.0234107 |
| HS6ST3 | heparan sulfate 6-O-sulfotransferase 3 | -0.0233218 |
| LMAN2 | lectin, mannose-binding 2 | -0.023289 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0232097 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0231172 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0230727 |
| CLMP | CXADR-like membrane protein | -0.0229991 |
| FUS | FUS RNA binding protein | -0.0227878 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0223484 |
| TUBB | tubulin, beta class I | -0.0217065 |
| JUN | jun proto-oncogene | -0.0216258 |
| SP100 | SP100 nuclear antigen | -0.0215873 |
| RPS16 | ribosomal protein S16 | -0.0212986 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0211308 |
| MAP1B | microtubule-associated protein 1B | -0.0208642 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.020544 |
| NRXN3 | neurexin 3 | -0.0201899 |
| NAV1 | neuron navigator 1 | -0.0201181 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0199433 |
| SNED1 | sushi, nidogen and EGF-like domains 1 | -0.0198273 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0194848 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0193015 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0190865 |
| TNNC1 | troponin C type 1 (slow) | -0.019069 |
| MKI67 | marker of proliferation Ki-67 | -0.0184476 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0184444 |
| NIBAN1 | niban apoptosis regulator 1 | -0.0183175 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0182499 |
| GLCCI1 | glucocorticoid induced 1 | -0.0182004 |
| DTNA | dystrobrevin, alpha | -0.0180846 |
| TUBA1B | tubulin, alpha 1b | -0.0177823 |
| CDK14 | cyclin-dependent kinase 14 | -0.017732 |
| OSMR | oncostatin M receptor | -0.0177316 |
| TJP1 | tight junction protein 1 | -0.0176126 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0176086 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0174545 |
| IL6ST | interleukin 6 signal transducer | -0.0174491 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0174415 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0171959 |
| HMGB1 | high mobility group box 1 | -0.0171656 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0171133 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0170656 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0170383 |
| PGK1 | phosphoglycerate kinase 1 | -0.0170118 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0169628 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0168741 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0168636 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0168302 |
