| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pravastatin (sodium)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.105049 |
| PRELID2 | PRELI domain containing 2 | 0.0827946 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0799784 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0765773 |
| MT2A | metallothionein 2A | 0.0760492 |
| GOLGA4 | golgin A4 | 0.0731133 |
| FDPS | farnesyl diphosphate synthase | 0.0701481 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0698368 |
| RPS3 | ribosomal protein S3 | 0.0679818 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0677192 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0673599 |
| KIAA1217 | KIAA1217 | 0.0668441 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0655612 |
| OGA | O-GlcNAcase | 0.0642526 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0635919 |
| ZNF292 | zinc finger protein 292 | 0.0606734 |
| SMC5 | structural maintenance of chromosomes 5 | 0.0595605 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0588528 |
| TMEM41B | transmembrane protein 41B | 0.058652 |
| TXNRD1 | thioredoxin reductase 1 | 0.0566235 |
| RPS8 | ribosomal protein S8 | 0.0539767 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0512646 |
| RPS2 | ribosomal protein S2 | 0.0499518 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0498069 |
| RPL23 | ribosomal protein L23 | 0.049697 |
| NF1 | neurofibromin 1 | 0.0489224 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.047399 |
| RPL26 | ribosomal protein L26 | 0.0464423 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0463721 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0456394 |
| ZNF148 | zinc finger protein 148 | 0.0427939 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0426549 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0424848 |
| PCBP2 | poly(rC) binding protein 2 | 0.0423899 |
| RPL37A | ribosomal protein L37a | 0.042111 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0409642 |
| RPS6 | ribosomal protein S6 | 0.0409487 |
| RPL9 | ribosomal protein L9 | 0.0408542 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0408132 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0407317 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0405717 |
| RPL13A | ribosomal protein L13a | 0.0399498 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0398382 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.039479 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0387393 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0386542 |
| SERINC1 | serine incorporator 1 | 0.0378929 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0372367 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0372278 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0370727 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0370265 |
| CENPF | centromere protein F, 350/400kDa | 0.0364693 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0362899 |
| RPL12 | ribosomal protein L12 | 0.036158 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0357684 |
| RBM26 | RNA binding motif protein 26 | 0.0357188 |
| UBXN4 | UBX domain protein 4 | 0.0355527 |
| VMP1 | vacuole membrane protein 1 | 0.0354294 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0353205 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0352022 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0351786 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0347661 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.0341171 |
| GOLGB1 | golgin B1 | 0.0337743 |
| TMF1 | TATA element modulatory factor 1 | 0.0336259 |
| EPN2 | epsin 2 | 0.0333185 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0333157 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0333121 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0332854 |
| RCOR1 | REST corepressor 1 | 0.0332232 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0331561 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.033084 |
| CIRSR | corepressor of RBPJ and splicing regulator | 0.0325638 |
| ATXN7 | ataxin 7 | 0.0325307 |
| HDAC8 | histone deacetylase 8 | 0.0319933 |
| TPR | translocated promoter region, nuclear basket protein | 0.0319874 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0319557 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0316512 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.031594 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0312764 |
| RPL11 | ribosomal protein L11 | 0.0312277 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0309727 |
| KIF5B | kinesin family member 5B | 0.0309596 |
| SMAP1 | small ArfGAP 1 | 0.0309048 |
| WDR26 | WD repeat domain 26 | 0.0308204 |
| RTN4 | reticulon 4 | 0.0308113 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0304966 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0303707 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0302179 |
| RAD51B | RAD51 paralog B | 0.0301487 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0299483 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.029776 |
| MCFD2 | multiple coagulation factor deficiency 2 | 0.029745 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0297153 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) | 0.0295778 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.0294207 |
| RPS12 | ribosomal protein S12 | 0.0293831 |
| CCNG2 | cyclin G2 | 0.0290865 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0289655 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0288136 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.176462 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.134051 |
| NDRG1 | N-myc downstream regulated 1 | -0.126624 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.103765 |
| AHNAK | AHNAK nucleoprotein | -0.102298 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0831887 |
| CTBP2 | C-terminal binding protein 2 | -0.073286 |
| HDLBP | high density lipoprotein binding protein | -0.0582561 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0517067 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.051093 |
| FTL | ferritin, light polypeptide | -0.0487074 |
| ACTG1 | actin gamma 1 | -0.0481444 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0480041 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0451115 |
| HMGB1 | high mobility group box 1 | -0.0447749 |
| FUS | FUS RNA binding protein | -0.0434071 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0407363 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0403335 |
| CCND1 | cyclin D1 | -0.0403294 |
| RIGI | RNA sensor RIG-I | -0.0402715 |
| MORF4L2 | mortality factor 4 like 2 | -0.0398896 |
| SCFD2 | sec1 family domain containing 2 | -0.0392503 |
| HMGA2 | high mobility group AT-hook 2 | -0.0388421 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0372498 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0357742 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0354585 |
| ENO1 | enolase 1, (alpha) | -0.0354494 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0348835 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0345786 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.033911 |
| WWOX | WW domain containing oxidoreductase | -0.0336968 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0336047 |
| VEGFA | vascular endothelial growth factor A | -0.0334818 |
| TLK1 | tousled-like kinase 1 | -0.0320939 |
| EZR | ezrin | -0.0320019 |
| LMNA | lamin A/C | -0.0317951 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0315532 |
| UBAP2 | ubiquitin associated protein 2 | -0.0314371 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0313166 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0310108 |
| NPR2 | natriuretic peptide receptor 2 | -0.0307795 |
| HLA-B | major histocompatibility complex, class I, B | -0.0306743 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0305954 |
| DSG2 | desmoglein 2 | -0.0305641 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0304517 |
| PKM | pyruvate kinase, muscle | -0.0302546 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0299638 |
| ARF1 | ADP-ribosylation factor 1 | -0.0297961 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0293913 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0291855 |
| H1-0 | H1.0 linker histone | -0.0289773 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0288187 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0287387 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0286992 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0286981 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0286664 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0285544 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0282673 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.028227 |
| HELZ | helicase with zinc finger | -0.0280714 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0279068 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0277896 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0274102 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | -0.027381 |
| KRT8 | keratin 8, type II | -0.0272567 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0272161 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.027047 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0269858 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.026776 |
| TAOK1 | TAO kinase 1 | -0.0267735 |
| FOXO3 | forkhead box O3 | -0.0266313 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0266046 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.0264047 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0262865 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0262712 |
| FLNA | filamin A, alpha | -0.0261634 |
| CHD4 | chromodomain helicase DNA binding protein 4 | -0.0261002 |
| BMP4 | bone morphogenetic protein 4 | -0.0260161 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0259738 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.025877 |
| PGK1 | phosphoglycerate kinase 1 | -0.0256088 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0254204 |
| TUBB | tubulin, beta class I | -0.0253014 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0252322 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0251849 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0249765 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0248338 |
| STIP1 | stress-induced phosphoprotein 1 | -0.024755 |
| STMN1 | stathmin 1 | -0.0244826 |
| TNS4 | tensin 4 | -0.0244607 |
| EIF4H | eukaryotic translation initiation factor 4H | -0.0242611 |
| JUN | jun proto-oncogene | -0.0237815 |
| LRRC23 | leucine rich repeat containing 23 | -0.0235183 |
| RPL4 | ribosomal protein L4 | -0.0234337 |
| NAV2 | neuron navigator 2 | -0.0233652 |
| TUBA1B | tubulin, alpha 1b | -0.0233643 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0231962 |
| PFKP | phosphofructokinase, platelet | -0.0231432 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0230525 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0229193 |
