| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pravastatin (sodium)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | 0.100157 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0923856 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0684286 |
| RPL37A | ribosomal protein L37a | 0.0566294 |
| AHNAK | AHNAK nucleoprotein | 0.055636 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0529559 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0476931 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0454695 |
| RPS12 | ribosomal protein S12 | 0.0451217 |
| MT2A | metallothionein 2A | 0.0445306 |
| SET | SET nuclear proto-oncogene | 0.0444228 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0434543 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0428058 |
| CBX3 | chromobox homolog 3 | 0.0427305 |
| OGA | O-GlcNAcase | 0.0419032 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0412574 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0412568 |
| SMAD3 | SMAD family member 3 | 0.0404399 |
| PAX8 | paired box 8 | 0.0401813 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0399061 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0396274 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0388604 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0385019 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0378053 |
| EZR | ezrin | 0.0377168 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0370694 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0367382 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0362867 |
| SEPTIN9 | septin 9 | 0.0358892 |
| NCKAP1 | NCK-associated protein 1 | 0.0347638 |
| RPS3 | ribosomal protein S3 | 0.0346794 |
| RPS17 | ribosomal protein S17 | 0.0346437 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0341899 |
| RNF145 | ring finger protein 145 | 0.034164 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0340322 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0337105 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0332499 |
| ZNF292 | zinc finger protein 292 | 0.0323767 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0321959 |
| AFDN | afadin, adherens junction formation factor | 0.0319335 |
| FLNB | filamin B, beta | 0.0316433 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0302809 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0295581 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0294257 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0293318 |
| MYEOV | myeloma overexpressed | 0.0291194 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0285002 |
| RPL31 | ribosomal protein L31 | 0.0284397 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0277979 |
| CCNY | cyclin Y | 0.0271952 |
| APP | amyloid beta (A4) precursor protein | 0.0270206 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0270036 |
| ASPH | aspartate beta-hydroxylase | 0.0269689 |
| DIAPH1 | diaphanous-related formin 1 | 0.0266208 |
| INSIG2 | insulin induced gene 2 | 0.0265564 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0263885 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0261372 |
| PLEC | plectin | 0.026047 |
| RPL3 | ribosomal protein L3 | 0.0260236 |
| DENND5A | DENN/MADD domain containing 5A | 0.0259929 |
| SERINC1 | serine incorporator 1 | 0.0259688 |
| YEATS2 | YEATS domain containing 2 | 0.0256084 |
| MYEF2 | myelin expression factor 2 | 0.0253782 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0251539 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0250248 |
| TMSB4X | thymosin beta 4, X-linked | 0.0248003 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0247978 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0245277 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0243627 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | 0.0243596 |
| FNBP1L | formin binding protein 1-like | 0.0237997 |
| TPM3 | tropomyosin 3 | 0.0229567 |
| RPL5 | ribosomal protein L5 | 0.0229245 |
| RPS8 | ribosomal protein S8 | 0.0225205 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0222876 |
| CD47 | CD47 molecule | 0.0220236 |
| SLTM | SAFB-like, transcription modulator | 0.0217726 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.021725 |
| FMNL2 | formin-like 2 | 0.021708 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0216543 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0213813 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.021257 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0212519 |
| WDR43 | WD repeat domain 43 | 0.021235 |
| RASA2 | RAS p21 protein activator 2 | 0.0211978 |
| RPS19 | ribosomal protein S19 | 0.0210939 |
| LAMC2 | laminin, gamma 2 | 0.0210834 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0208799 |
| COPA | coatomer protein complex, subunit alpha | 0.0208368 |
| VEGFA | vascular endothelial growth factor A | 0.0208251 |
| SEC61G | Sec61 gamma subunit | 0.0208106 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0207986 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0207486 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0207145 |
| ITGA6 | integrin, alpha 6 | 0.0206762 |
| ATP13A3 | ATPase type 13A3 | 0.0206368 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0204419 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0203494 |
| SPOPL | speckle-type POZ protein-like | 0.0201466 |
| YTHDC1 | YTH domain containing 1 | 0.0199956 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.349988 |
| ACTG1 | actin gamma 1 | -0.207371 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.123162 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.118355 |
| CCND1 | cyclin D1 | -0.0793406 |
| FTL | ferritin, light polypeptide | -0.0734963 |
| EGR1 | early growth response 1 | -0.0702161 |
| HMGA1 | high mobility group AT-hook 1 | -0.0663199 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0650554 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0645501 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0551803 |
| BICC1 | BicC family RNA binding protein 1 | -0.0529449 |
| FLNA | filamin A, alpha | -0.0528394 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0507454 |
| GOLGB1 | golgin B1 | -0.0501282 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0491067 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.047009 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0462329 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0461571 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0450189 |
| MAP4 | microtubule-associated protein 4 | -0.0422585 |
| RPLP0 | ribosomal protein, large, P0 | -0.0410138 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0389881 |
| FUS | FUS RNA binding protein | -0.0384662 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0382184 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0380695 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0376203 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0374988 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0371952 |
| HMGB1 | high mobility group box 1 | -0.0371488 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0370631 |
| ITGB8 | integrin, beta 8 | -0.0361428 |
| RPL12 | ribosomal protein L12 | -0.0360085 |
| RPL8 | ribosomal protein L8 | -0.0358028 |
| BPTF | bromodomain PHD finger transcription factor | -0.0353871 |
| DSG2 | desmoglein 2 | -0.0347375 |
| TAOK1 | TAO kinase 1 | -0.0347287 |
| HDLBP | high density lipoprotein binding protein | -0.034431 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0344093 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.033081 |
| RPS15 | ribosomal protein S15 | -0.032686 |
| ARF1 | ADP-ribosylation factor 1 | -0.0324933 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0324436 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0322387 |
| TXNRD1 | thioredoxin reductase 1 | -0.0314905 |
| RPS11 | ribosomal protein S11 | -0.0314762 |
| CCDC138 | coiled-coil domain containing 138 | -0.0314537 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0313498 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0312705 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0310144 |
| GOLGA4 | golgin A4 | -0.0307278 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.030513 |
| TPM4 | tropomyosin 4 | -0.0304574 |
| TPI1 | triosephosphate isomerase 1 | -0.0304017 |
| FIGN | fidgetin | -0.030184 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0297403 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0297098 |
| IRF1 | interferon regulatory factor 1 | -0.029416 |
| RPS5 | ribosomal protein S5 | -0.0293146 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0291503 |
| ERBIN | erbb2 interacting protein | -0.0290609 |
| WWC1 | WW and C2 domain containing 1 | -0.0288382 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0285282 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0284283 |
| SETD5 | SET domain containing 5 | -0.0283456 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0281887 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0280084 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0276825 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0276415 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0276132 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0272608 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.026939 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0269216 |
| RPL28 | ribosomal protein L28 | -0.0268972 |
| SVIL | supervillin | -0.02689 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0267969 |
| RPL32 | ribosomal protein L32 | -0.0267955 |
| PLCB4 | phospholipase C, beta 4 | -0.0266057 |
| MYO1E | myosin IE | -0.0262753 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0262619 |
| H3-3B | H3.3 histone B | -0.0262419 |
| TUBB | tubulin, beta class I | -0.0262337 |
| S100A10 | S100 calcium binding protein A10 | -0.0257276 |
| GNAS | GNAS complex locus | -0.0257107 |
| RPLP1 | ribosomal protein, large, P1 | -0.0256013 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0255514 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0250965 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0250359 |
| CLASP2 | cytoplasmic linker associated protein 2 | -0.0248318 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0246267 |
| POTEF | POTE ankyrin domain family, member F | -0.0244158 |
| PHIP | pleckstrin homology domain interacting protein | -0.0242964 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0242075 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0239211 |
| PTK2 | protein tyrosine kinase 2 | -0.0239126 |
| CDK13 | cyclin-dependent kinase 13 | -0.0239029 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0239006 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.023626 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0236028 |
| RANBP17 | RAN binding protein 17 | -0.0232654 |
