| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pravastatin (sodium)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0769328 |
| NDRG1 | N-myc downstream regulated 1 | 0.0754808 |
| TMSB10 | thymosin beta 10 | 0.0703937 |
| RPL23 | ribosomal protein L23 | 0.0564213 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0563655 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0535574 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.052497 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0493889 |
| RPS12 | ribosomal protein S12 | 0.0493782 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0478331 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0470559 |
| TOP1 | topoisomerase (DNA) I | 0.0469613 |
| RPL37A | ribosomal protein L37a | 0.0459477 |
| RPS17 | ribosomal protein S17 | 0.044995 |
| RPS3 | ribosomal protein S3 | 0.0436175 |
| TMEM41B | transmembrane protein 41B | 0.0433064 |
| CBX3 | chromobox homolog 3 | 0.0398598 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0396126 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0390318 |
| LDHA | lactate dehydrogenase A | 0.0385817 |
| SQSTM1 | sequestosome 1 | 0.0384657 |
| CCNY | cyclin Y | 0.0371905 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0369252 |
| FAM13A | family with sequence similarity 13, member A | 0.0358692 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0357554 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0352291 |
| VASP | vasodilator-stimulated phosphoprotein | 0.0346211 |
| RPL18 | ribosomal protein L18 | 0.0344866 |
| RAD21 | RAD21 homolog (S. pombe) | 0.033722 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0335011 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0333385 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.033329 |
| OGA | O-GlcNAcase | 0.0329019 |
| RNF145 | ring finger protein 145 | 0.0327195 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0313809 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0313567 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0313503 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0308885 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0308101 |
| SQLE | squalene epoxidase | 0.0307097 |
| WASF2 | WAS protein family, member 2 | 0.0302766 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0301996 |
| RACK1 | receptor for activated C kinase 1 | 0.0300307 |
| HYOU1 | hypoxia up-regulated 1 | 0.0296161 |
| NCKAP1 | NCK-associated protein 1 | 0.0295536 |
| NUP58 | nucleoporin 58 | 0.0292578 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0291169 |
| PGK1 | phosphoglycerate kinase 1 | 0.028329 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0281963 |
| RBM25 | RNA binding motif protein 25 | 0.0278841 |
| CENPF | centromere protein F, 350/400kDa | 0.0274191 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0273777 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0271364 |
| S100A6 | S100 calcium binding protein A6 | 0.0270931 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0270394 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0270085 |
| ABHD2 | abhydrolase domain containing 2 | 0.0268689 |
| ZNF292 | zinc finger protein 292 | 0.0266392 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0264902 |
| CENPE | centromere protein E, 312kDa | 0.0264151 |
| TJP2 | tight junction protein 2 | 0.0261479 |
| EREG | epiregulin | 0.0261433 |
| CKAP5 | cytoskeleton associated protein 5 | 0.025831 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0256095 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0255908 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0255663 |
| THOC2 | THO complex 2 | 0.0254883 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0254527 |
| SUZ12 | SUZ12 polycomb repressive complex 2 subunit | 0.0252692 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0252588 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.025241 |
| HDGF | hepatoma-derived growth factor | 0.0252286 |
| DIAPH3 | diaphanous-related formin 3 | 0.0252156 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | 0.0251708 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0250473 |
| ZFP36 | ZFP36 ring finger protein | 0.0250468 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0249204 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0247499 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0245733 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0244843 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0244202 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0242982 |
| MKI67 | marker of proliferation Ki-67 | 0.0242381 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0241932 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | 0.0241643 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0241231 |
| DBF4 | DBF4 zinc finger | 0.0240555 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0234461 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0234094 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | 0.0231927 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0223864 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0222502 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0221316 |
| VIM | vimentin | 0.0219198 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0219116 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0217504 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0216569 |
| ITGA6 | integrin, alpha 6 | 0.0216232 |
| HOXB6 | homeobox B6 | 0.0214554 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0214022 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | -0.173782 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.154097 |
| KRT20 | keratin 20, type I | -0.13466 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.133402 |
| LMO7 | LIM domain 7 | -0.123326 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.122665 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.11643 |
| TJP1 | tight junction protein 1 | -0.0982176 |
| EZR | ezrin | -0.0978277 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0917573 |
| ACTG1 | actin gamma 1 | -0.0894065 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0856324 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.074914 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0737107 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0719534 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.071601 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0681605 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0669761 |
| EGR1 | early growth response 1 | -0.0661915 |
| PDZD8 | PDZ domain containing 8 | -0.0659062 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0657754 |
| RBM39 | RNA binding motif protein 39 | -0.0645571 |
| RND3 | Rho family GTPase 3 | -0.0644441 |
| MYO1E | myosin IE | -0.0629151 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0628115 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.061289 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0612011 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0596629 |
| AHNAK | AHNAK nucleoprotein | -0.0591044 |
| RPS2 | ribosomal protein S2 | -0.0584187 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0573734 |
| EXPH5 | exophilin 5 | -0.056376 |
| TRIB1 | tribbles pseudokinase 1 | -0.0554666 |
| FHL2 | four and a half LIM domains 2 | -0.055454 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0549929 |
| S100A10 | S100 calcium binding protein A10 | -0.0547862 |
| ETV6 | ets variant 6 | -0.0532407 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0521268 |
| JMJD1C | jumonji domain containing 1C | -0.0517561 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0515405 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0507887 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0505947 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0493917 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0492625 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0492249 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0485941 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0479242 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0477721 |
| VCL | vinculin | -0.0476814 |
| KRT8 | keratin 8, type II | -0.0475486 |
| NTN4 | netrin 4 | -0.0473806 |
| FRY | furry homolog (Drosophila) | -0.0473476 |
| FBXO32 | F-box protein 32 | -0.0469066 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0461764 |
| RNF213 | ring finger protein 213 | -0.0460031 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0459206 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0458432 |
| POF1B | premature ovarian failure, 1B | -0.0444782 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0443797 |
| LAMA4 | laminin, alpha 4 | -0.044331 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0441647 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0437676 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0425541 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0417662 |
| RPL21 | ribosomal protein L21 | -0.0417197 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0410274 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0409945 |
| SMAD3 | SMAD family member 3 | -0.0407063 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0406528 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.0405741 |
| WWC1 | WW and C2 domain containing 1 | -0.0405175 |
| KRT18 | keratin 18, type I | -0.0403527 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0399543 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0397531 |
| RAB10 | RAB10, member RAS oncogene family | -0.0396255 |
| RPL7 | ribosomal protein L7 | -0.0388556 |
| JUN | jun proto-oncogene | -0.0388112 |
| KRT19 | keratin 19, type I | -0.0384375 |
| BCL2L1 | BCL2-like 1 | -0.0383209 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.037983 |
| SGMS2 | sphingomyelin synthase 2 | -0.0368245 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0362366 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0361705 |
| TMEM123 | transmembrane protein 123 | -0.0360205 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0352941 |
| MACC1 | metastasis associated in colon cancer 1 | -0.034929 |
| RASEF | RAS and EF-hand domain containing | -0.0347779 |
| IL6ST | interleukin 6 signal transducer | -0.0345663 |
| PGCKA1 | PDCD10 and GCKIII kinases associated 1 | -0.0341751 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0340473 |
| MYO5B | myosin VB | -0.0336775 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0335919 |
| CDK13 | cyclin-dependent kinase 13 | -0.0335585 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0333473 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0332794 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0329414 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0328817 |
| TLE4 | transducin-like enhancer of split 4 | -0.0328569 |
| EMP1 | epithelial membrane protein 1 | -0.0328283 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.032786 |
