| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pravastatin (sodium)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.246181 |
| STC1 | stanniocalcin 1 | 0.0960691 |
| ITGA6 | integrin, alpha 6 | 0.0958358 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0949743 |
| PODXL | podocalyxin-like | 0.0873194 |
| LAMC2 | laminin, gamma 2 | 0.0736969 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0715372 |
| MYO10 | myosin X | 0.0703936 |
| MEF2A | myocyte enhancer factor 2A | 0.0700202 |
| FOSL1 | FOS-like antigen 1 | 0.0658202 |
| SQLE | squalene epoxidase | 0.06377 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0601545 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0586273 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0583729 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0535127 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0534687 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0531241 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0527181 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0483612 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0483582 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0455804 |
| NAV2 | neuron navigator 2 | 0.0454638 |
| OGA | O-GlcNAcase | 0.0447182 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0445193 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0414598 |
| POTEF | POTE ankyrin domain family, member F | 0.0411134 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0399079 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0395285 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0394271 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0393392 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0393089 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0391429 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0370354 |
| CSNK1E | casein kinase 1, epsilon | 0.0369023 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0359977 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0348532 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0347964 |
| KIAA0040 | KIAA0040 | 0.0343922 |
| AMOTL1 | angiomotin like 1 | 0.0338239 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0336156 |
| PCDH1 | protocadherin 1 | 0.0330589 |
| PLEKHG5 | pleckstrin homology domain containing, family G (with RhoGef domain) member 5 | 0.0329736 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0327318 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0325459 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0311134 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0310279 |
| CD47 | CD47 molecule | 0.0307765 |
| ATP13A3 | ATPase type 13A3 | 0.0305247 |
| ANXA5 | annexin A5 | 0.0299354 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0299302 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0296739 |
| RPS8 | ribosomal protein S8 | 0.029586 |
| CALB1 | calbindin 1, 28kDa | 0.0293814 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0288363 |
| EFHD2 | EF-hand domain family, member D2 | 0.0280891 |
| MEGF6 | multiple EGF-like-domains 6 | 0.027352 |
| CLMB | calcimembrin | 0.0273059 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0270467 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0267375 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0265378 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0264909 |
| LIMA1 | LIM domain and actin binding 1 | 0.0264288 |
| CDCP1 | CUB domain containing protein 1 | 0.0262886 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.026215 |
| FNBP1L | formin binding protein 1-like | 0.0261397 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0259841 |
| PTHLH | parathyroid hormone-like hormone | 0.0258132 |
| RPS12 | ribosomal protein S12 | 0.0253096 |
| LUZP1 | leucine zipper protein 1 | 0.025107 |
| THOC2 | THO complex 2 | 0.0246951 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0246739 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0242782 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0241867 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0240028 |
| S100A2 | S100 calcium binding protein A2 | 0.0239575 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0238035 |
| CD9 | CD9 molecule | 0.0237469 |
| DUSP6 | dual specificity phosphatase 6 | 0.0236982 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0235703 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0234977 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0234621 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0233298 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0233042 |
| LAMA5 | laminin, alpha 5 | 0.0232661 |
| SLK | STE20-like kinase | 0.0232294 |
| RNF217 | ring finger protein 217 | 0.0232146 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0229571 |
| ZNF292 | zinc finger protein 292 | 0.0229406 |
| VIM | vimentin | 0.0227945 |
| CBX3 | chromobox homolog 3 | 0.0226977 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0226049 |
| HDGF | hepatoma-derived growth factor | 0.0221919 |
| RAI1 | retinoic acid induced 1 | 0.0221049 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0218727 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0217614 |
| RASA3 | RAS p21 protein activator 3 | 0.0216783 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0216172 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0215632 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | 0.0215315 |
| PLEK2 | pleckstrin 2 | 0.0214408 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.225604 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.172126 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0995099 |
| IGF2 | insulin-like growth factor 2 | -0.0901145 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0892767 |
| LMO7 | LIM domain 7 | -0.0872759 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0872411 |
| RBM39 | RNA binding motif protein 39 | -0.0857221 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0841107 |
| CD44 | CD44 molecule (Indian blood group) | -0.0827848 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.079533 |
| FN1 | fibronectin 1 | -0.0766295 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0761078 |
| CLU | clusterin | -0.0740506 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0740212 |
| H1-0 | H1.0 linker histone | -0.0700407 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0685784 |
| TMSB4X | thymosin beta 4, X-linked | -0.0647916 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0632399 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0624202 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0622861 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0595134 |
| FOXP1 | forkhead box P1 | -0.0578814 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0575489 |
| AOPEP | aminopeptidase O (putative) | -0.0557729 |
| CUL4B | cullin 4B | -0.0555991 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0549528 |
| S100A10 | S100 calcium binding protein A10 | -0.0543276 |
| OSMR | oncostatin M receptor | -0.0539612 |
| ARF1 | ADP-ribosylation factor 1 | -0.0537663 |
| GNAS | GNAS complex locus | -0.0531489 |
| INTS6 | integrator complex subunit 6 | -0.0522256 |
| RIGI | RNA sensor RIG-I | -0.049679 |
| PALLD | palladin, cytoskeletal associated protein | -0.0478847 |
| MECOM | MDS1 and EVI1 complex locus | -0.0468907 |
| RPS2 | ribosomal protein S2 | -0.0464203 |
| MYOF | myoferlin | -0.045778 |
| SULF1 | sulfatase 1 | -0.0455267 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0454846 |
| VCL | vinculin | -0.0442373 |
| TXNIP | thioredoxin interacting protein | -0.0439475 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0439403 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.043417 |
| DST | dystonin | -0.0428318 |
| GOLGB1 | golgin B1 | -0.0428187 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0425236 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0397524 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0397409 |
| ANXA1 | annexin A1 | -0.0394339 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0392382 |
| HLA-B | major histocompatibility complex, class I, B | -0.0389272 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0387737 |
| CLTC | clathrin, heavy chain (Hc) | -0.038717 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.0385139 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0382321 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0377637 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.037674 |
| SULF2 | sulfatase 2 | -0.0374999 |
| YBX3 | Y box binding protein 3 | -0.0374764 |
| TKT | transketolase | -0.0372883 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.037257 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0368437 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0366947 |
| ADAR | adenosine deaminase, RNA-specific | -0.0366056 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.036279 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0361032 |
| ZNF217 | zinc finger protein 217 | -0.035621 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0356044 |
| RAI14 | retinoic acid induced 14 | -0.0350886 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0349177 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0348077 |
| MORF4L2 | mortality factor 4 like 2 | -0.0347501 |
| IL6ST | interleukin 6 signal transducer | -0.0341917 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0340091 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0337758 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.033659 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0335217 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0334237 |
| HDLBP | high density lipoprotein binding protein | -0.0328644 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.032841 |
| SP100 | SP100 nuclear antigen | -0.0325854 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0321158 |
| TXNRD1 | thioredoxin reductase 1 | -0.0315733 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.031411 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0314071 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0312794 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0311811 |
| UBC | ubiquitin C | -0.0311734 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0308651 |
| RAB10 | RAB10, member RAS oncogene family | -0.0308119 |
| CDK13 | cyclin-dependent kinase 13 | -0.0306927 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0304811 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0304271 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0302983 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0299588 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0299562 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0299191 |
| ACTG1 | actin gamma 1 | -0.0298613 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0297258 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.029716 |
