| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pravastatin (sodium)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.167186 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.145636 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.120371 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.101846 |
| ATP13A3 | ATPase type 13A3 | 0.0779356 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0761716 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0744948 |
| ZNF841 | zinc finger protein 841 | 0.0741964 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0690393 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0651858 |
| B2M | beta-2-microglobulin | 0.0624078 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0559011 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0537263 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0537209 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0533771 |
| ZNF292 | zinc finger protein 292 | 0.0516855 |
| SLC12A8 | solute carrier family 12, member 8 | 0.0508261 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0505498 |
| SET | SET nuclear proto-oncogene | 0.0504794 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.049786 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0491641 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0465291 |
| PLIN2 | perilipin 2 | 0.0429198 |
| NAV2 | neuron navigator 2 | 0.0427152 |
| DTNA | dystrobrevin, alpha | 0.0423828 |
| ADM | adrenomedullin | 0.0423452 |
| CCNL1 | cyclin L1 | 0.0419923 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0392588 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0382592 |
| MSN | moesin | 0.0363921 |
| LIMA1 | LIM domain and actin binding 1 | 0.0351903 |
| MYOF | myoferlin | 0.0350178 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0346674 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | 0.0340776 |
| TMSB4X | thymosin beta 4, X-linked | 0.0340458 |
| NUP58 | nucleoporin 58 | 0.0333261 |
| PDE10A | phosphodiesterase 10A | 0.0325827 |
| VIM | vimentin | 0.03229 |
| MMP12 | matrix metallopeptidase 12 | 0.0319651 |
| TPM3 | tropomyosin 3 | 0.0319468 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0316269 |
| HDGF | hepatoma-derived growth factor | 0.0315308 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0308555 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0306543 |
| PCBP2 | poly(rC) binding protein 2 | 0.0306139 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0305328 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0304105 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0302777 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0301399 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0299867 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0299613 |
| RAI1 | retinoic acid induced 1 | 0.029367 |
| S100A6 | S100 calcium binding protein A6 | 0.0293181 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 | 0.0285204 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0283407 |
| RAB8B | RAB8B, member RAS oncogene family | 0.028232 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0281606 |
| INSIG2 | insulin induced gene 2 | 0.0279279 |
| FOSL1 | FOS-like antigen 1 | 0.0278496 |
| RNF144B | ring finger protein 144B | 0.0278241 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0277417 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0276448 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0274121 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0268924 |
| CADM1 | cell adhesion molecule 1 | 0.0268598 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0268579 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0268007 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.026658 |
| VEGFA | vascular endothelial growth factor A | 0.0265529 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0265467 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0264389 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0259167 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0258824 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0258143 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0255746 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0253236 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.025273 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0250957 |
| POTEF | POTE ankyrin domain family, member F | 0.0247497 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0246971 |
| RBM25 | RNA binding motif protein 25 | 0.0244369 |
| NGLY1 | N-glycanase 1 | 0.0244134 |
| AXL | AXL receptor tyrosine kinase | 0.023818 |
| STC2 | stanniocalcin 2 | 0.0238046 |
| NCOR2 | nuclear receptor corepressor 2 | 0.023717 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0234803 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0233564 |
| NKTR | natural killer cell triggering receptor | 0.0230974 |
| FBXO42 | F-box protein 42 | 0.0230878 |
| FNBP4 | formin binding protein 4 | 0.0230709 |
| FLNB | filamin B, beta | 0.0230513 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0230029 |
| RUNX1 | runt-related transcription factor 1 | 0.0227769 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0223288 |
| DENND5A | DENN/MADD domain containing 5A | 0.0223048 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0222503 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.022139 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0221261 |
| DENND4C | DENN/MADD domain containing 4C | 0.0220415 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0219293 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.280665 |
| HLA-B | major histocompatibility complex, class I, B | -0.159126 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.158021 |
| EXT1 | exostosin glycosyltransferase 1 | -0.134933 |
| FTL | ferritin, light polypeptide | -0.114081 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0800029 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0778705 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0769479 |
| ACTG1 | actin gamma 1 | -0.076365 |
| TXNRD1 | thioredoxin reductase 1 | -0.075717 |
| HLA-C | major histocompatibility complex, class I, C | -0.0669502 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0551415 |
| MT1X | metallothionein 1X | -0.0537545 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0535528 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0525946 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0483926 |
| GLIS3 | GLIS family zinc finger 3 | -0.0443085 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0441963 |
| HMGB1 | high mobility group box 1 | -0.0434138 |
| ANXA2 | annexin A2 | -0.0429334 |
| OSMR | oncostatin M receptor | -0.0419782 |
| CTSD | cathepsin D | -0.041687 |
| TMSB10 | thymosin beta 10 | -0.0413254 |
| AHNAK | AHNAK nucleoprotein | -0.0412263 |
| RPL35A | ribosomal protein L35a | -0.0408898 |
| LOX | lysyl oxidase | -0.0405111 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.040324 |
| CD44 | CD44 molecule (Indian blood group) | -0.0389912 |
| ARF1 | ADP-ribosylation factor 1 | -0.038253 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0375336 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0367323 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0366105 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0360058 |
| MAP1B | microtubule-associated protein 1B | -0.0359936 |
| FUS | FUS RNA binding protein | -0.035915 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0351308 |
| INTS6 | integrator complex subunit 6 | -0.0348028 |
| SMYD3 | SET and MYND domain containing 3 | -0.0345977 |
| CCND1 | cyclin D1 | -0.0342067 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0340823 |
| MAP4 | microtubule-associated protein 4 | -0.0340625 |
| FN1 | fibronectin 1 | -0.033875 |
| FLNA | filamin A, alpha | -0.0330493 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0329027 |
| TUBB | tubulin, beta class I | -0.0328072 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0326719 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.032384 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0321854 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0321412 |
| LAMP1 | lysosomal-associated membrane protein 1 | -0.0317915 |
| DEK | DEK proto-oncogene | -0.0315805 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0312565 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0300501 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0289896 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0280528 |
| HDLBP | high density lipoprotein binding protein | -0.0277866 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0274009 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0272909 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0272137 |
| VDAC1 | voltage-dependent anion channel 1 | -0.026245 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0262314 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.026227 |
| RAB7A | RAB7A, member RAS oncogene family | -0.026115 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0259589 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0257588 |
| RTN3 | reticulon 3 | -0.0255753 |
| GOLGA3 | golgin A3 | -0.0251157 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0250945 |
| ZXDC | ZXD family zinc finger C | -0.0250877 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0250401 |
| DPYD | dihydropyrimidine dehydrogenase | -0.02503 |
| NABP1 | nucleic acid binding protein 1 | -0.0249215 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0246565 |
| ZNF804A | zinc finger protein 804A | -0.024371 |
| PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | -0.0241913 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0240808 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0238754 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0235935 |
| CANX | calnexin | -0.0235696 |
| RANBP17 | RAN binding protein 17 | -0.0235613 |
| VCL | vinculin | -0.0235123 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0235032 |
| GOLGB1 | golgin B1 | -0.0234705 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0233 |
| CAVIN1 | caveolae associated protein 1 | -0.0227801 |
| CDK12 | cyclin-dependent kinase 12 | -0.0226786 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0226017 |
| RRBP1 | ribosome binding protein 1 | -0.0225048 |
| PLSCR1 | phospholipid scramblase 1 | -0.0222295 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0221261 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0220422 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0216682 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0212957 |
| SPIDR | scaffolding protein involved in DNA repair | -0.021156 |
| RPLP1 | ribosomal protein, large, P1 | -0.0210613 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.020599 |
| E2F3 | E2F transcription factor 3 | -0.020582 |
| DIAPH3 | diaphanous-related formin 3 | -0.0204805 |
| EGR1 | early growth response 1 | -0.0204024 |
| RPL38 | ribosomal protein L38 | -0.0203459 |
