| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pravastatin (sodium)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.13028 |
| DTNA | dystrobrevin, alpha | 0.127386 |
| RPS6 | ribosomal protein S6 | 0.112471 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.108313 |
| RPS12 | ribosomal protein S12 | 0.103069 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.092143 |
| RPL37A | ribosomal protein L37a | 0.0884225 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0818576 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0797467 |
| RPS17 | ribosomal protein S17 | 0.0740512 |
| LIMA1 | LIM domain and actin binding 1 | 0.065741 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0654566 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0620776 |
| MSN | moesin | 0.0613558 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0574045 |
| RPS8 | ribosomal protein S8 | 0.0531665 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.052038 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.049046 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0487311 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0479248 |
| NUP58 | nucleoporin 58 | 0.045085 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0449808 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0441092 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0440119 |
| RPS3 | ribosomal protein S3 | 0.0431539 |
| MT2A | metallothionein 2A | 0.0429847 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0424284 |
| ZNF292 | zinc finger protein 292 | 0.0410307 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0401589 |
| CALD1 | caldesmon 1 | 0.0378938 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0378518 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0369163 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0367222 |
| MALT1 | MALT1 paracaspase | 0.0362715 |
| ASPH | aspartate beta-hydroxylase | 0.0360366 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.03601 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0359627 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0342432 |
| RPL23 | ribosomal protein L23 | 0.0337933 |
| EFNA5 | ephrin-A5 | 0.0330392 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.032788 |
| RNF145 | ring finger protein 145 | 0.0325825 |
| RBM25 | RNA binding motif protein 25 | 0.0323979 |
| RPS19 | ribosomal protein S19 | 0.0317394 |
| SET | SET nuclear proto-oncogene | 0.0313543 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0312469 |
| RAB8B | RAB8B, member RAS oncogene family | 0.031026 |
| RPL5 | ribosomal protein L5 | 0.0310254 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0304338 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0299397 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0293309 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0288575 |
| PKM | pyruvate kinase, muscle | 0.0288455 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0288366 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0285676 |
| CORO1C | coronin, actin binding protein, 1C | 0.0283535 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0283221 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0282844 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0282189 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0281661 |
| RPL26 | ribosomal protein L26 | 0.0279618 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0278895 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0276718 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0275889 |
| RPS2 | ribosomal protein S2 | 0.0273949 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0272522 |
| TMSB10 | thymosin beta 10 | 0.0268969 |
| RACK1 | receptor for activated C kinase 1 | 0.026528 |
| RPS18 | ribosomal protein S18 | 0.0264412 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.026351 |
| DIAPH3 | diaphanous-related formin 3 | 0.0262126 |
| PRKCE | protein kinase C, epsilon | 0.0258853 |
| HDGF | hepatoma-derived growth factor | 0.0256338 |
| TLE4 | transducin-like enhancer of split 4 | 0.0250412 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0244819 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0241595 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0239013 |
| RPLP1 | ribosomal protein, large, P1 | 0.0237951 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0237322 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0236679 |
| TPM3 | tropomyosin 3 | 0.0233439 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0232686 |
| KIF5B | kinesin family member 5B | 0.0228525 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0223861 |
| BRD2 | bromodomain containing 2 | 0.0222945 |
| DENR | density-regulated protein | 0.0222664 |
| PDS5B | PDS5 cohesin associated factor B | 0.0222521 |
| ENKUR | enkurin, TRPC channel interacting protein | 0.0222456 |
| ITGA6 | integrin, alpha 6 | 0.0220293 |
| ANKRD11 | ankyrin repeat domain 11 | 0.021852 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0218205 |
| SMAP1 | small ArfGAP 1 | 0.0210581 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0208939 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0206452 |
| RPS14 | ribosomal protein S14 | 0.0205338 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0205177 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0204337 |
| RTN4 | reticulon 4 | 0.0204192 |
| PCBP2 | poly(rC) binding protein 2 | 0.0203501 |
| HDAC9 | histone deacetylase 9 | 0.020236 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.521006 |
| ACTG1 | actin gamma 1 | -0.12654 |
| AHNAK | AHNAK nucleoprotein | -0.122951 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0848728 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0822098 |
| FTL | ferritin, light polypeptide | -0.0564253 |
| HMGA1 | high mobility group AT-hook 1 | -0.0540202 |
| CTSB | cathepsin B | -0.0521209 |
| VCL | vinculin | -0.0501323 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0492156 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.049112 |
| PTCHD4 | patched domain containing 4 | -0.0490581 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0427553 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0425287 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0418993 |
| RIGI | RNA sensor RIG-I | -0.0408945 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0398024 |
| GPC6 | glypican 6 | -0.0393571 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0386255 |
| H1-0 | H1.0 linker histone | -0.0380882 |
| NF1 | neurofibromin 1 | -0.0371904 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0360206 |
| EMP1 | epithelial membrane protein 1 | -0.0357479 |
| FN1 | fibronectin 1 | -0.034678 |
| FOXP1 | forkhead box P1 | -0.0343952 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0337613 |
| NABP1 | nucleic acid binding protein 1 | -0.0331223 |
| MMP12 | matrix metallopeptidase 12 | -0.0321696 |
| CDK6 | cyclin-dependent kinase 6 | -0.0318135 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0310889 |
| ERBIN | erbb2 interacting protein | -0.0309128 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0309097 |
| PTMA | prothymosin, alpha | -0.0301693 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0299534 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0286366 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0283162 |
| ZNF217 | zinc finger protein 217 | -0.0282954 |
| CANX | calnexin | -0.0277409 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0275521 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0269823 |
| APP | amyloid beta (A4) precursor protein | -0.026942 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0267392 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0261769 |
| HMGB1 | high mobility group box 1 | -0.0254614 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0254052 |
| NTM | neurotrimin | -0.0253608 |
| MAP4 | microtubule-associated protein 4 | -0.025125 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0248954 |
| RNF213 | ring finger protein 213 | -0.0247527 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.024529 |
| FUS | FUS RNA binding protein | -0.0244957 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0243217 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0241002 |
| HLA-E | major histocompatibility complex, class I, E | -0.0239232 |
| UBC | ubiquitin C | -0.023842 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0237988 |
| TXNRD1 | thioredoxin reductase 1 | -0.0237273 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.023707 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0235784 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0234948 |
| HDLBP | high density lipoprotein binding protein | -0.0234746 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0234162 |
| MSR1 | macrophage scavenger receptor 1 | -0.0234013 |
| KYNU | kynureninase | -0.0232939 |
| RPL6 | ribosomal protein L6 | -0.0232745 |
| ARF1 | ADP-ribosylation factor 1 | -0.0231596 |
| TUBB | tubulin, beta class I | -0.022879 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0227943 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0226706 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.022535 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -0.0224809 |
| EGR1 | early growth response 1 | -0.0223919 |
| ATXN1 | ataxin 1 | -0.0223859 |
| RPL8 | ribosomal protein L8 | -0.0219189 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0219026 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0218958 |
| IER3 | immediate early response 3 | -0.0218773 |
| RBM39 | RNA binding motif protein 39 | -0.0215778 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0214502 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0214243 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0211056 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0210721 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0210156 |
| FLNA | filamin A, alpha | -0.0210005 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0208472 |
| RPL38 | ribosomal protein L38 | -0.020597 |
| ETV6 | ets variant 6 | -0.0204041 |
| RPL14 | ribosomal protein L14 | -0.0204034 |
| CDK12 | cyclin-dependent kinase 12 | -0.0202494 |
| RAI14 | retinoic acid induced 14 | -0.020147 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0201082 |
| FBN2 | fibrillin 2 | -0.0199596 |
| CUX1 | cut-like homeobox 1 | -0.0197996 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0195956 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.019497 |
| PRSS23 | protease, serine, 23 | -0.0193077 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0192929 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0191218 |
| RAB7A | RAB7A, member RAS oncogene family | -0.01904 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.018958 |
