| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pravastatin (sodium)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | 0.124703 |
| GOLGA4 | golgin A4 | 0.105786 |
| EREG | epiregulin | 0.0982245 |
| RPS12 | ribosomal protein S12 | 0.0819302 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0738489 |
| KIF5B | kinesin family member 5B | 0.0736619 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0727282 |
| RPL37A | ribosomal protein L37a | 0.0726247 |
| RPS8 | ribosomal protein S8 | 0.0714861 |
| RNF145 | ring finger protein 145 | 0.0692025 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0676224 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0652772 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0629887 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0614786 |
| DSCAM | Down syndrome cell adhesion molecule | 0.05992 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0571924 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0535221 |
| TNS4 | tensin 4 | 0.0534648 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0522242 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0522154 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0520323 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0517369 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0515398 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0510489 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0499782 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0496725 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0493231 |
| OGA | O-GlcNAcase | 0.0492754 |
| FLNB | filamin B, beta | 0.0491107 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0487192 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0473914 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0471197 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0470346 |
| S100P | S100 calcium binding protein P | 0.0469243 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0467108 |
| RPS3 | ribosomal protein S3 | 0.0460988 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.045748 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0453442 |
| TOP1 | topoisomerase (DNA) I | 0.0450307 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0446237 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0446208 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0446019 |
| RNF43 | ring finger protein 43 | 0.0437701 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0435489 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0431354 |
| LMO7 | LIM domain 7 | 0.0430848 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0429863 |
| YTHDC1 | YTH domain containing 1 | 0.0429167 |
| FAM13A | family with sequence similarity 13, member A | 0.0420306 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0414573 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0411323 |
| AREG | amphiregulin | 0.0409781 |
| PTEN | phosphatase and tensin homolog | 0.0406315 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0406122 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0384473 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0382754 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0375972 |
| LIMA1 | LIM domain and actin binding 1 | 0.0372364 |
| RPS17 | ribosomal protein S17 | 0.037038 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0369541 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0366971 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0365682 |
| RPL26 | ribosomal protein L26 | 0.036418 |
| GOLGB1 | golgin B1 | 0.0359729 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0357702 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0356454 |
| SLK | STE20-like kinase | 0.0356275 |
| PTMA | prothymosin, alpha | 0.0355722 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0355704 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0354661 |
| THOC2 | THO complex 2 | 0.0351584 |
| ITGA6 | integrin, alpha 6 | 0.034761 |
| TMF1 | TATA element modulatory factor 1 | 0.0345457 |
| PRELID2 | PRELI domain containing 2 | 0.0340973 |
| CTBP2 | C-terminal binding protein 2 | 0.0340326 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0336959 |
| NEBL | nebulette | 0.0333933 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0333083 |
| VEGFA | vascular endothelial growth factor A | 0.033255 |
| NKTR | natural killer cell triggering receptor | 0.0332506 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0329842 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.032853 |
| RTN4 | reticulon 4 | 0.0327368 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0326724 |
| ANXA1 | annexin A1 | 0.0324993 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0324338 |
| RPL9 | ribosomal protein L9 | 0.0323019 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0322708 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.031632 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0315862 |
| FDPS | farnesyl diphosphate synthase | 0.0312751 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0311373 |
| RSF1 | remodeling and spacing factor 1 | 0.0310274 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0308026 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0306011 |
| GDF15 | growth differentiation factor 15 | 0.0305968 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0305295 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0304702 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0303844 |
| TRIM2 | tripartite motif containing 2 | 0.0300206 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.388225 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.126979 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0738697 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0719016 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.071051 |
| MT2A | metallothionein 2A | -0.0710172 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0675007 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0608914 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0523301 |
| MYO1E | myosin IE | -0.0522465 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0514678 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0509203 |
| PGK1 | phosphoglycerate kinase 1 | -0.0506912 |
| VCL | vinculin | -0.0479389 |
| ACTG1 | actin gamma 1 | -0.0477488 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0438198 |
| KRT19 | keratin 19, type I | -0.041901 |
| HMGA1 | high mobility group AT-hook 1 | -0.0394781 |
| CALR | calreticulin | -0.0377331 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0375755 |
| LAMA4 | laminin, alpha 4 | -0.0368683 |
| EGR1 | early growth response 1 | -0.0358722 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0357642 |
| RPL12 | ribosomal protein L12 | -0.035592 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0350631 |
| MUC17 | mucin 17, cell surface associated | -0.0347343 |
| ABLIM1 | actin binding LIM protein 1 | -0.0338637 |
| PIGR | polymeric immunoglobulin receptor | -0.0326535 |
| H1-0 | H1.0 linker histone | -0.0324187 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0322424 |
| FHIT | fragile histidine triad | -0.0317432 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0309952 |
| NDRG1 | N-myc downstream regulated 1 | -0.0309721 |
| HMGB1 | high mobility group box 1 | -0.0309167 |
| ANXA2 | annexin A2 | -0.0306881 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0306807 |
| MT1E | metallothionein 1E | -0.0297024 |
| MT1X | metallothionein 1X | -0.0293027 |
| ACTN4 | actinin, alpha 4 | -0.0288618 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0288234 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.028424 |
| ENO1 | enolase 1, (alpha) | -0.027926 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0263474 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0259537 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0257238 |
| RPS15 | ribosomal protein S15 | -0.0253097 |
| NPSR1 | neuropeptide S receptor 1 | -0.0252096 |
| CCND1 | cyclin D1 | -0.0248358 |
| SETX | senataxin | -0.0248054 |
| FTL | ferritin, light polypeptide | -0.0237602 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0232119 |
| TUBB | tubulin, beta class I | -0.0231684 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0229882 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0228975 |
| PDLIM5 | PDZ and LIM domain 5 | -0.022659 |
| RPLP0 | ribosomal protein, large, P0 | -0.0225595 |
| BSG | basigin (Ok blood group) | -0.022536 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0224695 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0220531 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0218688 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0214259 |
| RPL35 | ribosomal protein L35 | -0.0208541 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0206313 |
| CLOCK | clock circadian regulator | -0.0206272 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0202114 |
| RAD51B | RAD51 paralog B | -0.0200252 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0200078 |
| TUBA1B | tubulin, alpha 1b | -0.0199723 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0199446 |
| RPL32 | ribosomal protein L32 | -0.0198623 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0196077 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0194281 |
| ARF1 | ADP-ribosylation factor 1 | -0.0194266 |
| HMGB2 | high mobility group box 2 | -0.018975 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0186862 |
| RPS11 | ribosomal protein S11 | -0.0186725 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0186581 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) | -0.0184513 |
| FOXP1 | forkhead box P1 | -0.0182539 |
| DIAPH3 | diaphanous-related formin 3 | -0.0182078 |
| PCNX2 | pecanex 2 | -0.0181986 |
| RPLP1 | ribosomal protein, large, P1 | -0.0181809 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0181287 |
| TFRC | transferrin receptor | -0.0180331 |
| RYBP | RING1 and YY1 binding protein | -0.0180321 |
| FN1 | fibronectin 1 | -0.0179898 |
| TMSB10 | thymosin beta 10 | -0.0179395 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0178812 |
| RESF1 | retroelement silencing factor 1 | -0.0178201 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0174094 |
| RHOA | ras homolog family member A | -0.0174053 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0172967 |
| RPL8 | ribosomal protein L8 | -0.017147 |
| CD44 | CD44 molecule (Indian blood group) | -0.0171036 |
| ECT2 | epithelial cell transforming 2 | -0.0170989 |
| SMYD3 | SET and MYND domain containing 3 | -0.0168758 |
| EGFR | epidermal growth factor receptor | -0.0167743 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0167665 |
| POTEF | POTE ankyrin domain family, member F | -0.0167201 |
| RPS10 | ribosomal protein S10 | -0.0167099 |
