| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pravastatin (sodium)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS12 | ribosomal protein S12 | 0.191173 |
| RPS17 | ribosomal protein S17 | 0.0940366 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0919907 |
| RPS6 | ribosomal protein S6 | 0.0896251 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0893437 |
| FLNB | filamin B, beta | 0.0887212 |
| RPS3 | ribosomal protein S3 | 0.0777453 |
| RPL37A | ribosomal protein L37a | 0.0767646 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0710961 |
| RPS8 | ribosomal protein S8 | 0.070097 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0678492 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0676052 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0660981 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.059817 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0596627 |
| MSI2 | musashi RNA-binding protein 2 | 0.0590066 |
| PRELID2 | PRELI domain containing 2 | 0.0548247 |
| MYO1E | myosin IE | 0.0543983 |
| FOXO1 | forkhead box O1 | 0.0535059 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.052953 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0527301 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0525645 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.052313 |
| RNF145 | ring finger protein 145 | 0.0497838 |
| LMO7 | LIM domain 7 | 0.0496874 |
| RPS19 | ribosomal protein S19 | 0.0491079 |
| RAD51B | RAD51 paralog B | 0.0489522 |
| ITGA6 | integrin, alpha 6 | 0.0489097 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0462676 |
| DSPP | dentin sialophosphoprotein | 0.0462491 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0461444 |
| RPL5 | ribosomal protein L5 | 0.0459338 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0455023 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0454215 |
| LIMA1 | LIM domain and actin binding 1 | 0.0452636 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0448965 |
| ABHD17C | abhydrolase domain containing 17C | 0.0433467 |
| SMAD3 | SMAD family member 3 | 0.0428935 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0422644 |
| RPL26 | ribosomal protein L26 | 0.0421136 |
| EREG | epiregulin | 0.0399543 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0392351 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0391967 |
| MYOF | myoferlin | 0.0389008 |
| RBM25 | RNA binding motif protein 25 | 0.038659 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0377777 |
| RPL23 | ribosomal protein L23 | 0.0375075 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0372148 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0361718 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0359344 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0359339 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0357365 |
| SLTM | SAFB-like, transcription modulator | 0.0354893 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.035137 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.034817 |
| PRRC2C | proline-rich coiled-coil 2C | 0.034782 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0335115 |
| AREG | amphiregulin | 0.0324528 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0324031 |
| TRIM2 | tripartite motif containing 2 | 0.0323917 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0322723 |
| ACTN4 | actinin, alpha 4 | 0.0319243 |
| VCL | vinculin | 0.0317061 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0316459 |
| ASPH | aspartate beta-hydroxylase | 0.0313844 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0311212 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0308226 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0307485 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0305758 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0301811 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0295986 |
| NKTR | natural killer cell triggering receptor | 0.029565 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0294971 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0292472 |
| MED13L | mediator complex subunit 13-like | 0.0290833 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0289815 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0286182 |
| MYO6 | myosin VI | 0.0284945 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0284671 |
| CD47 | CD47 molecule | 0.0284099 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0284028 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0283022 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0275012 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0273805 |
| RPL30 | ribosomal protein L30 | 0.0272697 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.027055 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.026621 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0264703 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0264602 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0263753 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0260787 |
| UBE3A | ubiquitin protein ligase E3A | 0.0260261 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0258228 |
| LAMB3 | laminin, beta 3 | 0.0257139 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0257036 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0255196 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0252749 |
| CBX3 | chromobox homolog 3 | 0.0251022 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0249963 |
| VMP1 | vacuole membrane protein 1 | 0.0249054 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.27399 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.157228 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.144016 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.12786 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.124968 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.105326 |
| RPLP0 | ribosomal protein, large, P0 | -0.0831449 |
| ACTG1 | actin gamma 1 | -0.082509 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0778058 |
| CANX | calnexin | -0.0730898 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0687184 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0683401 |
| HDLBP | high density lipoprotein binding protein | -0.0611986 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0580153 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0578099 |
| RPL8 | ribosomal protein L8 | -0.0570674 |
| DSG2 | desmoglein 2 | -0.0520636 |
| RPL12 | ribosomal protein L12 | -0.0509705 |
| CALU | calumenin | -0.0489823 |
| EGR1 | early growth response 1 | -0.0484297 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0432624 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0411775 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0385583 |
| KRT18 | keratin 18, type I | -0.0376088 |
| AHNAK | AHNAK nucleoprotein | -0.0366503 |
| AGR2 | anterior gradient 2 | -0.0366031 |
| RRBP1 | ribosome binding protein 1 | -0.0364477 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0350487 |
| HMGA1 | high mobility group AT-hook 1 | -0.0343263 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0337462 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.033412 |
| RPS11 | ribosomal protein S11 | -0.0333586 |
| H1-0 | H1.0 linker histone | -0.0327341 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0320405 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0319478 |
| RPL38 | ribosomal protein L38 | -0.0317081 |
| ANXA2 | annexin A2 | -0.0307418 |
| FUS | FUS RNA binding protein | -0.0307044 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0298132 |
| PTMA | prothymosin, alpha | -0.0293142 |
| RPS24 | ribosomal protein S24 | -0.0282674 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0279534 |
| ENO1 | enolase 1, (alpha) | -0.0278696 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0278396 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0277242 |
| ARF1 | ADP-ribosylation factor 1 | -0.027156 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0266811 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0266651 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0263339 |
| HMGB1 | high mobility group box 1 | -0.026207 |
| MX1 | MX dynamin-like GTPase 1 | -0.0258967 |
| RPS23 | ribosomal protein S23 | -0.025703 |
| HLA-B | major histocompatibility complex, class I, B | -0.0254877 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0254836 |
| IRF1 | interferon regulatory factor 1 | -0.0253023 |
| RPS15 | ribosomal protein S15 | -0.0252957 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0246467 |
| KRT19 | keratin 19, type I | -0.0246117 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.024543 |
| RPS16 | ribosomal protein S16 | -0.0244677 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0243723 |
| NDRG1 | N-myc downstream regulated 1 | -0.0240289 |
| TMEM123 | transmembrane protein 123 | -0.0239857 |
| UBC | ubiquitin C | -0.0237563 |
| TUBB | tubulin, beta class I | -0.0232726 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0228979 |
| LDHA | lactate dehydrogenase A | -0.0226315 |
| GDF15 | growth differentiation factor 15 | -0.022313 |
| TC2N | tandem C2 domains, nuclear | -0.0222808 |
| TPI1 | triosephosphate isomerase 1 | -0.02212 |
| HMGB2 | high mobility group box 2 | -0.0220105 |
| MORF4L2 | mortality factor 4 like 2 | -0.0219113 |
| RHOA | ras homolog family member A | -0.021735 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0217098 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.021647 |
| S100A10 | S100 calcium binding protein A10 | -0.0213628 |
| OXSR1 | oxidative stress responsive 1 | -0.021293 |
| DEK | DEK proto-oncogene | -0.0212877 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0211701 |
| HBP1 | HMG-box transcription factor 1 | -0.020893 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0208086 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0206963 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0205806 |
| XAF1 | XIAP associated factor 1 | -0.0205795 |
| TXNIP | thioredoxin interacting protein | -0.0205691 |
| ARCN1 | archain 1 | -0.0199515 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0198382 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0198267 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0197493 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0196691 |
| FTL | ferritin, light polypeptide | -0.0196595 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0196367 |
| ZNF207 | zinc finger protein 207 | -0.0196345 |
| ATF4 | activating transcription factor 4 | -0.0196118 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0196106 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0195751 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0195074 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0194921 |
| UBE2I | ubiquitin-conjugating enzyme E2I | -0.019437 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.0192117 |
