| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pravastatin (sodium)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.226091 |
| TXNRD1 | thioredoxin reductase 1 | 0.12044 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.10643 |
| RAI1 | retinoic acid induced 1 | 0.0954091 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0821011 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0728543 |
| RPS12 | ribosomal protein S12 | 0.0669037 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0645439 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0604506 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0557208 |
| FMNL2 | formin-like 2 | 0.0515993 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0510417 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0490249 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0479215 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0462464 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0459756 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0455627 |
| CENPF | centromere protein F, 350/400kDa | 0.044161 |
| USP34 | ubiquitin specific peptidase 34 | 0.0435146 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0429411 |
| RPS8 | ribosomal protein S8 | 0.0422386 |
| TMEM41B | transmembrane protein 41B | 0.0415224 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0409771 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0394462 |
| RPL37A | ribosomal protein L37a | 0.0383689 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0372843 |
| MCL1 | myeloid cell leukemia 1 | 0.037223 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0363583 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0360186 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0357025 |
| RPS17 | ribosomal protein S17 | 0.0353104 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0335885 |
| RPS6 | ribosomal protein S6 | 0.0332886 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.03319 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0328478 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0323978 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.030115 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0297412 |
| KIAA1958 | KIAA1958 | 0.0295759 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0294485 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0293951 |
| RPS18 | ribosomal protein S18 | 0.0293038 |
| TPM3 | tropomyosin 3 | 0.0290311 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0289826 |
| MKI67 | marker of proliferation Ki-67 | 0.0288824 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0285934 |
| SET | SET nuclear proto-oncogene | 0.0282415 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0281575 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0276478 |
| MSN | moesin | 0.026936 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0267616 |
| EREG | epiregulin | 0.0264799 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0262866 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0261759 |
| RTN4 | reticulon 4 | 0.0257861 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0257211 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0251982 |
| NUP58 | nucleoporin 58 | 0.0248921 |
| MYO10 | myosin X | 0.0248446 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0247359 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0244491 |
| RPS19 | ribosomal protein S19 | 0.0244314 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0243983 |
| NGLY1 | N-glycanase 1 | 0.0243906 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0242801 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0239159 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0236167 |
| RRM2 | ribonucleotide reductase M2 | 0.0235111 |
| POM121 | POM121 transmembrane nucleoporin | 0.0234567 |
| HJURP | Holliday junction recognition protein | 0.0231343 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0231331 |
| FNIP1 | folliculin interacting protein 1 | 0.0225651 |
| DENND5A | DENN/MADD domain containing 5A | 0.0222596 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0221784 |
| EHBP1 | EH domain binding protein 1 | 0.0219856 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0217871 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0216595 |
| CAPRIN2 | caprin family member 2 | 0.0215971 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0212681 |
| HDGF | hepatoma-derived growth factor | 0.0211537 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0211451 |
| YEATS2 | YEATS domain containing 2 | 0.0211084 |
| PYGB | phosphorylase, glycogen; brain | 0.0209199 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0208317 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0207149 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0206858 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0206691 |
| EZR | ezrin | 0.0206115 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0205947 |
| RPL23 | ribosomal protein L23 | 0.0204987 |
| WDR26 | WD repeat domain 26 | 0.0204859 |
| PRDX1 | peroxiredoxin 1 | 0.0204764 |
| NAV2 | neuron navigator 2 | 0.0204693 |
| RBM25 | RNA binding motif protein 25 | 0.0202537 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0201773 |
| CDK19 | cyclin-dependent kinase 19 | 0.0200619 |
| OFD1 | oral-facial-digital syndrome 1 | 0.0200103 |
| TMSB4X | thymosin beta 4, X-linked | 0.0198193 |
| RCOR1 | REST corepressor 1 | 0.019801 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0197761 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.345445 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.226404 |
| TP63 | tumor protein p63 | -0.114016 |
| AHNAK | AHNAK nucleoprotein | -0.0991651 |
| PTMA | prothymosin, alpha | -0.0903537 |
| CD44 | CD44 molecule (Indian blood group) | -0.0789137 |
| HLA-B | major histocompatibility complex, class I, B | -0.0787297 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0778963 |
| CANX | calnexin | -0.070274 |
| ACTG1 | actin gamma 1 | -0.0671168 |
| CADM2 | cell adhesion molecule 2 | -0.0666908 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0640839 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0623594 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0617883 |
| RIGI | RNA sensor RIG-I | -0.0574697 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0549255 |
| FTL | ferritin, light polypeptide | -0.0522493 |
| RNF213 | ring finger protein 213 | -0.0499744 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0492716 |
| DST | dystonin | -0.0489892 |
| HMGA1 | high mobility group AT-hook 1 | -0.0479752 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0448815 |
| MT1X | metallothionein 1X | -0.0436967 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0436546 |
| TNS3 | tensin 3 | -0.0429571 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0427673 |
| VCL | vinculin | -0.0424715 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0422632 |
| SP100 | SP100 nuclear antigen | -0.041317 |
| MT2A | metallothionein 2A | -0.0409509 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0408273 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0399446 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0395638 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0388138 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0387111 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0382961 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0380959 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0377981 |
| ZNF217 | zinc finger protein 217 | -0.0375126 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0369896 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0369579 |
| APP | amyloid beta (A4) precursor protein | -0.0367007 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0365092 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0364818 |
| FUS | FUS RNA binding protein | -0.0361465 |
| TXNIP | thioredoxin interacting protein | -0.0358552 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0358013 |
| EPHA4 | EPH receptor A4 | -0.0351157 |
| TMSB10 | thymosin beta 10 | -0.0350425 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0348043 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.034466 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0333567 |
| H1-0 | H1.0 linker histone | -0.033107 |
| PLSCR1 | phospholipid scramblase 1 | -0.0330916 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0324761 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0317178 |
| GNAS | GNAS complex locus | -0.0307941 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0305511 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0298862 |
| RPL12 | ribosomal protein L12 | -0.0298555 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0291985 |
| ANXA2 | annexin A2 | -0.0291568 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0289152 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0283146 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0281763 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0276441 |
| HMGB1 | high mobility group box 1 | -0.0275061 |
| DEK | DEK proto-oncogene | -0.0267285 |
| TUBB | tubulin, beta class I | -0.0267273 |
| TMEM123 | transmembrane protein 123 | -0.0263178 |
| RPLP0 | ribosomal protein, large, P0 | -0.0261985 |
| SMYD3 | SET and MYND domain containing 3 | -0.0257106 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0254981 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0249122 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0248044 |
| RBM39 | RNA binding motif protein 39 | -0.0246636 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0234798 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0234472 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0232232 |
| EIF4H | eukaryotic translation initiation factor 4H | -0.0230754 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0229073 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.022836 |
| RPL8 | ribosomal protein L8 | -0.0225974 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0225056 |
| ARF1 | ADP-ribosylation factor 1 | -0.0224073 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0223677 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0221301 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0220864 |
| GLG1 | golgi glycoprotein 1 | -0.0220595 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0220526 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0220114 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0219552 |
| EXOC4 | exocyst complex component 4 | -0.0218769 |
| EPB41 | erythrocyte membrane protein band 4.1 | -0.0216726 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0214618 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0210709 |
| WTAP | Wilms tumor 1 associated protein | -0.0207677 |
| HDLBP | high density lipoprotein binding protein | -0.0206016 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0205886 |
| LDHA | lactate dehydrogenase A | -0.0205264 |
