| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pravastatin (sodium)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.203245 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.185393 |
| SMAD3 | SMAD family member 3 | 0.0986733 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0979942 |
| NAV2 | neuron navigator 2 | 0.0787059 |
| RPS12 | ribosomal protein S12 | 0.0774301 |
| EFNA5 | ephrin-A5 | 0.0724523 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0718299 |
| FAM13A | family with sequence similarity 13, member A | 0.070396 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0670082 |
| PRELID2 | PRELI domain containing 2 | 0.0663609 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.063807 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0578497 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0549923 |
| RPL37A | ribosomal protein L37a | 0.050623 |
| NGLY1 | N-glycanase 1 | 0.0506127 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0502841 |
| RUNX1 | runt-related transcription factor 1 | 0.0501236 |
| GOLGA4 | golgin A4 | 0.04853 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0474275 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0472073 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0461192 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0460878 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0445237 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0439135 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0436464 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0434804 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0431602 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.042836 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0427715 |
| USP34 | ubiquitin specific peptidase 34 | 0.0425382 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0425012 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0417502 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0409261 |
| RPS3 | ribosomal protein S3 | 0.0396887 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0396155 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.039457 |
| SIK3 | SIK family kinase 3 | 0.0382275 |
| FAM107B | family with sequence similarity 107, member B | 0.0380102 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0376903 |
| ATXN1 | ataxin 1 | 0.0364206 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.036103 |
| YEATS2 | YEATS domain containing 2 | 0.0358842 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0358594 |
| OGA | O-GlcNAcase | 0.0358252 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0353903 |
| TGM2 | transglutaminase 2 | 0.0353341 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0351669 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0351043 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0350887 |
| LRRC49 | leucine rich repeat containing 49 | 0.0346889 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0344399 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0342961 |
| RPS17 | ribosomal protein S17 | 0.0342372 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.033351 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.032789 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta | 0.0325247 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0313022 |
| ANGPTL4 | angiopoietin-like 4 | 0.0311996 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0309557 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0304996 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0298981 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0290223 |
| MYO1B | myosin IB | 0.0286402 |
| VMP1 | vacuole membrane protein 1 | 0.0285823 |
| RPS19 | ribosomal protein S19 | 0.0282374 |
| THOC2 | THO complex 2 | 0.027954 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0278314 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0278068 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0276339 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0272255 |
| RPLP1 | ribosomal protein, large, P1 | 0.0266371 |
| RPS6 | ribosomal protein S6 | 0.0263522 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0260693 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0260654 |
| POM121 | POM121 transmembrane nucleoporin | 0.0258097 |
| FAM3C | family with sequence similarity 3, member C | 0.0256998 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0256586 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0255925 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0254399 |
| SS18 | synovial sarcoma translocation, chromosome 18 | 0.0252623 |
| OFD1 | oral-facial-digital syndrome 1 | 0.0251727 |
| FLNB | filamin B, beta | 0.0250598 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 0.0248893 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0248836 |
| OPTN | optineurin | 0.0248354 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0248254 |
| VEGFA | vascular endothelial growth factor A | 0.0246556 |
| ZNF292 | zinc finger protein 292 | 0.0244561 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0243211 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0240715 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.023948 |
| TPR | translocated promoter region, nuclear basket protein | 0.0239415 |
| RAD51B | RAD51 paralog B | 0.0237556 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0237032 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0236663 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0236517 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0235825 |
| USP24 | ubiquitin specific peptidase 24 | 0.0235458 |
| CENPF | centromere protein F, 350/400kDa | 0.0235235 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.322709 |
| FN1 | fibronectin 1 | -0.183341 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.163964 |
| LOX | lysyl oxidase | -0.131775 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0995974 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.089467 |
| FTL | ferritin, light polypeptide | -0.0799944 |
| RBM39 | RNA binding motif protein 39 | -0.0722535 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.069957 |
| AHNAK | AHNAK nucleoprotein | -0.0674369 |
| GLCCI1 | glucocorticoid induced 1 | -0.066521 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0650941 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0637105 |
| NDRG1 | N-myc downstream regulated 1 | -0.063227 |
| NRG1 | neuregulin 1 | -0.059875 |
| PTMA | prothymosin, alpha | -0.0595401 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0589848 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0577648 |
| IER3 | immediate early response 3 | -0.0571215 |
| EGR1 | early growth response 1 | -0.0536142 |
| CD44 | CD44 molecule (Indian blood group) | -0.0521131 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0510087 |
| HMGA1 | high mobility group AT-hook 1 | -0.0507609 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0501087 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.048084 |
| CANX | calnexin | -0.0468874 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0464606 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0449636 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0441011 |
| NTN4 | netrin 4 | -0.0434348 |
| ENO1 | enolase 1, (alpha) | -0.0409423 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0403957 |
| H1-0 | H1.0 linker histone | -0.0397107 |
| RAI14 | retinoic acid induced 14 | -0.0393752 |
| FBXO11 | F-box protein 11 | -0.039231 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0382943 |
| ACTG1 | actin gamma 1 | -0.0369783 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0363047 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0362493 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0362287 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0359606 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0357885 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0349656 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0336945 |
| SYAP1 | synapse associated protein 1 | -0.033291 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0330925 |
| HDLBP | high density lipoprotein binding protein | -0.0328021 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0324921 |
| CALU | calumenin | -0.0319185 |
| PCBP2 | poly(rC) binding protein 2 | -0.0317767 |
| ERBIN | erbb2 interacting protein | -0.031447 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0314123 |
| MEF2A | myocyte enhancer factor 2A | -0.0312893 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0310997 |
| MAP1B | microtubule-associated protein 1B | -0.0309511 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.030808 |
| JUN | jun proto-oncogene | -0.0302812 |
| GNAS | GNAS complex locus | -0.0297851 |
| MECOM | MDS1 and EVI1 complex locus | -0.0297379 |
| S100A10 | S100 calcium binding protein A10 | -0.0290667 |
| CLIC4 | chloride intracellular channel 4 | -0.0283123 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0266229 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0265991 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0265786 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.026556 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0260931 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0260764 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0252068 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0250352 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0248643 |
| ANXA2 | annexin A2 | -0.0247178 |
| CDK14 | cyclin-dependent kinase 14 | -0.0243331 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0242628 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0241039 |
| SYT1 | synaptotagmin I | -0.0240943 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0239794 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0239247 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0236362 |
| GPC6 | glypican 6 | -0.0236285 |
| PRR16 | proline rich 16 | -0.0235267 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0231006 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0229533 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0228015 |
| ENOSF1 | enolase superfamily member 1 | -0.0227505 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0227441 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0227387 |
| HBP1 | HMG-box transcription factor 1 | -0.0226955 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0225852 |
| KYNU | kynureninase | -0.0224335 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0223038 |
| TPI1 | triosephosphate isomerase 1 | -0.0220682 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0220561 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0220054 |
| RNF213 | ring finger protein 213 | -0.0219879 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0217844 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0216736 |
| PGK1 | phosphoglycerate kinase 1 | -0.0215817 |
| WLS | wntless Wnt ligand secretion mediator | -0.0215686 |
| EIF4H | eukaryotic translation initiation factor 4H | -0.0215226 |
| VRK2 | vaccinia related kinase 2 | -0.0214751 |
