| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pravastatin (sodium)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.180011 |
| PGK1 | phosphoglycerate kinase 1 | 0.107193 |
| UBC | ubiquitin C | 0.102 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0876983 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0829687 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0804054 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0789001 |
| SQSTM1 | sequestosome 1 | 0.0737045 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0728732 |
| OGA | O-GlcNAcase | 0.0706937 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0698876 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0692491 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0689429 |
| RUNX1 | runt-related transcription factor 1 | 0.0687755 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0678953 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0672 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0653748 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0649196 |
| SBF2 | SET binding factor 2 | 0.0630155 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0622937 |
| FTL | ferritin, light polypeptide | 0.0618727 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0590725 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0577987 |
| RPS8 | ribosomal protein S8 | 0.0568401 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0557195 |
| FRYL | FRY-like | 0.0554344 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0551149 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0546995 |
| RPS3 | ribosomal protein S3 | 0.0534752 |
| CANX | calnexin | 0.0529488 |
| PHF20 | PHD finger protein 20 | 0.0525451 |
| RPL37A | ribosomal protein L37a | 0.0520214 |
| RPL7 | ribosomal protein L7 | 0.0513659 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0502308 |
| TXNRD1 | thioredoxin reductase 1 | 0.0501521 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0499457 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0497867 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0494984 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0484286 |
| RPS12 | ribosomal protein S12 | 0.0479194 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0476436 |
| CUL3 | cullin 3 | 0.047619 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0463558 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.046202 |
| GNAS | GNAS complex locus | 0.0461182 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.044861 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0444304 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0441912 |
| RIOK3 | RIO kinase 3 | 0.0438668 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0422716 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0416422 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0416276 |
| ENO1 | enolase 1, (alpha) | 0.0413737 |
| SETD5 | SET domain containing 5 | 0.0411651 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0406529 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0403714 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0401402 |
| CYRIB | CYFIP related Rac1 interactor B | 0.0399609 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0399174 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.039721 |
| SPAG9 | sperm associated antigen 9 | 0.0391868 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0389596 |
| RABGAP1 | RAB GTPase activating protein 1 | 0.0388043 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0385634 |
| RPS6 | ribosomal protein S6 | 0.0380009 |
| PRELID2 | PRELI domain containing 2 | 0.037625 |
| SFTPA2 | surfactant protein A2 | 0.0374093 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0367866 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0363849 |
| ZNF638 | zinc finger protein 638 | 0.0363201 |
| ZNF207 | zinc finger protein 207 | 0.0362838 |
| WDR45B | WD repeat domain 45B | 0.0355082 |
| RPL9 | ribosomal protein L9 | 0.0353085 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.034947 |
| AHNAK | AHNAK nucleoprotein | 0.0341536 |
| PDE10A | phosphodiesterase 10A | 0.0341134 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0339678 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.033871 |
| RLF | rearranged L-myc fusion | 0.0338645 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.033062 |
| APP | amyloid beta (A4) precursor protein | 0.0330381 |
| MSI2 | musashi RNA-binding protein 2 | 0.0327549 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0327138 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.032507 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0324265 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0323631 |
| ERBIN | erbb2 interacting protein | 0.0319602 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0315907 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0315703 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0314088 |
| NCKAP1 | NCK-associated protein 1 | 0.0313831 |
| IST1 | increased sodium tolerance 1 homolog (yeast) | 0.0312042 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0311141 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0306938 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.030675 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0302844 |
| RNF145 | ring finger protein 145 | 0.0290854 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0290079 |
| CALR | calreticulin | 0.0286005 |
| TPI1 | triosephosphate isomerase 1 | 0.0282085 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.157918 |
| VIM | vimentin | -0.155103 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.147561 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.12976 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.126872 |
| EGFR | epidermal growth factor receptor | -0.123986 |
| MYO1E | myosin IE | -0.121866 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.11084 |
| INHBA | inhibin, beta A | -0.0859624 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0855501 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0824423 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.082405 |
| COL1A1 | collagen, type I, alpha 1 | -0.0804665 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0782777 |
| HMGA2 | high mobility group AT-hook 2 | -0.0775477 |
| MMP1 | matrix metallopeptidase 1 | -0.0753042 |
| BPTF | bromodomain PHD finger transcription factor | -0.0729449 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0727915 |
| LAMB3 | laminin, beta 3 | -0.0715268 |
| RORA | RAR-related orphan receptor A | -0.0706549 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0700636 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0692801 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0667183 |
| GPC6 | glypican 6 | -0.0663679 |
| VMP1 | vacuole membrane protein 1 | -0.0663222 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0647749 |
| PRKCA | protein kinase C, alpha | -0.0615318 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0613124 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0611266 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0604735 |
| FN1 | fibronectin 1 | -0.0599929 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0592291 |
| STC1 | stanniocalcin 1 | -0.0570214 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0565645 |
| ATP13A3 | ATPase type 13A3 | -0.0560951 |
| TNNC1 | troponin C type 1 (slow) | -0.0552692 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0540057 |
| RPL34 | ribosomal protein L34 | -0.0522428 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0521423 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0513889 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0509415 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0506924 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0497943 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0491559 |
| RTN4 | reticulon 4 | -0.0477141 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0476619 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0470375 |
| ITGA6 | integrin, alpha 6 | -0.0465478 |
| JMJD1C | jumonji domain containing 1C | -0.045979 |
| GPHN | gephyrin | -0.0454623 |
| NDRG1 | N-myc downstream regulated 1 | -0.0452097 |
| SYAP1 | synapse associated protein 1 | -0.0450523 |
| NF1 | neurofibromin 1 | -0.0432445 |
| SMYD3 | SET and MYND domain containing 3 | -0.0426842 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0426582 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0416415 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0413822 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0409409 |
| PTK2 | protein tyrosine kinase 2 | -0.0409119 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0404248 |
| LAMA4 | laminin, alpha 4 | -0.0400716 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0383172 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0373148 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0368821 |
| RNF213 | ring finger protein 213 | -0.036099 |
| ATXN1 | ataxin 1 | -0.0359929 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0354519 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0348047 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0345828 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0343886 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0342855 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0340023 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0339118 |
| EFNA5 | ephrin-A5 | -0.0337831 |
| RPS24 | ribosomal protein S24 | -0.0335417 |
| CLTC | clathrin, heavy chain (Hc) | -0.0333331 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0325293 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0324787 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0324215 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0322835 |
| RPL35A | ribosomal protein L35a | -0.032113 |
| RPS23 | ribosomal protein S23 | -0.0319353 |
| IER3 | immediate early response 3 | -0.0317271 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0316316 |
| MCL1 | myeloid cell leukemia 1 | -0.0316289 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0306203 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0305671 |
| TOP1 | topoisomerase (DNA) I | -0.0299961 |
| CADM1 | cell adhesion molecule 1 | -0.0299766 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0299426 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | -0.0298172 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0297206 |
| EGR1 | early growth response 1 | -0.0292822 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0282705 |
| SEPTIN9 | septin 9 | -0.0279014 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0278029 |
| RAD51B | RAD51 paralog B | -0.0272501 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0268349 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0264255 |
| ACTG1 | actin gamma 1 | -0.0263821 |
