| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pravastatin (sodium)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.325906 |
| VIM | vimentin | 0.139552 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.139392 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0897945 |
| AHNAK | AHNAK nucleoprotein | 0.0884838 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.076797 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.064344 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0587574 |
| S100A6 | S100 calcium binding protein A6 | 0.054699 |
| OGA | O-GlcNAcase | 0.0486718 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0474723 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0469829 |
| ZNF292 | zinc finger protein 292 | 0.0450945 |
| FBL | fibrillarin | 0.0445773 |
| AFAP1 | actin filament associated protein 1 | 0.0443794 |
| PDE10A | phosphodiesterase 10A | 0.0415701 |
| RPS3 | ribosomal protein S3 | 0.0410154 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0403928 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.038556 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0383295 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.037619 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0371312 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0360285 |
| DST | dystonin | 0.0344761 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0338563 |
| TMEM41B | transmembrane protein 41B | 0.0337412 |
| SEPTIN9 | septin 9 | 0.0333921 |
| SMAD3 | SMAD family member 3 | 0.0333757 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0332653 |
| RBM25 | RNA binding motif protein 25 | 0.0331173 |
| RPS12 | ribosomal protein S12 | 0.0323898 |
| SNX14 | sorting nexin 14 | 0.0315827 |
| ATP13A3 | ATPase type 13A3 | 0.0314553 |
| CDK19 | cyclin-dependent kinase 19 | 0.0312169 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0302999 |
| ACTN4 | actinin, alpha 4 | 0.0298122 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0294645 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0274718 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0273087 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0267007 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0263358 |
| SET | SET nuclear proto-oncogene | 0.0253415 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0251721 |
| APP | amyloid beta (A4) precursor protein | 0.0246505 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0245572 |
| DHX32 | DEAH (Asp-Glu-Ala-His) box polypeptide 32 | 0.0244938 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0226327 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0219351 |
| RTN4 | reticulon 4 | 0.0216592 |
| MYOF | myoferlin | 0.0214584 |
| RPL4 | ribosomal protein L4 | 0.0213752 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0213341 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0209669 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0208121 |
| PCBP2 | poly(rC) binding protein 2 | 0.020718 |
| THOC2 | THO complex 2 | 0.0206868 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.020602 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0205236 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0204989 |
| KLF6 | Kruppel-like factor 6 | 0.020425 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0203278 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0202719 |
| FDPS | farnesyl diphosphate synthase | 0.0200721 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0200159 |
| KNOP1 | lysine-rich nucleolar protein 1 | 0.0197565 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0195667 |
| GRK5 | G protein-coupled receptor kinase 5 | 0.0195202 |
| PDGFB | platelet-derived growth factor beta polypeptide | 0.0192527 |
| FBXL4 | F-box and leucine-rich repeat protein 4 | 0.0191209 |
| PRELID2 | PRELI domain containing 2 | 0.0190904 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.018902 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.018394 |
| RPL26 | ribosomal protein L26 | 0.0183126 |
| RAI1 | retinoic acid induced 1 | 0.0182844 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.018262 |
| SBF2 | SET binding factor 2 | 0.0182478 |
| SMAP1 | small ArfGAP 1 | 0.0180428 |
| USP34 | ubiquitin specific peptidase 34 | 0.0180315 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0180261 |
| MT2A | metallothionein 2A | 0.0178206 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0177332 |
| CACNG8 | calcium channel, voltage-dependent, gamma subunit 8 | 0.0177103 |
| SERINC1 | serine incorporator 1 | 0.0176694 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0175569 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0174341 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0173694 |
| RUNX1 | runt-related transcription factor 1 | 0.0171574 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0169504 |
| ANGPTL4 | angiopoietin-like 4 | 0.0167975 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0167591 |
| RASA2 | RAS p21 protein activator 2 | 0.0165979 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0165414 |
| ANLN | anillin, actin binding protein | 0.016485 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0164344 |
| SQLE | squalene epoxidase | 0.0163964 |
| TPD52 | tumor protein D52 | 0.0163148 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0162883 |
| AFDN | afadin, adherens junction formation factor | 0.0162418 |
| CAVIN1 | caveolae associated protein 1 | 0.0162165 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0160566 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.376387 |
| VCL | vinculin | -0.124427 |
| RPS16 | ribosomal protein S16 | -0.099057 |
| FTL | ferritin, light polypeptide | -0.0862547 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0839878 |
| EGR1 | early growth response 1 | -0.0817127 |
| RPL35A | ribosomal protein L35a | -0.0772753 |
| TMSB10 | thymosin beta 10 | -0.0695828 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0661464 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0613779 |
| CTSD | cathepsin D | -0.0608272 |
| ACTG1 | actin gamma 1 | -0.0585793 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0566555 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.054319 |
| PKM | pyruvate kinase, muscle | -0.0517057 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0507216 |
| MED29 | mediator complex subunit 29 | -0.0493461 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | -0.0481747 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0481393 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0469113 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0450837 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0434904 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0432315 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0420989 |
| RPLP1 | ribosomal protein, large, P1 | -0.0413719 |
| HMGA1 | high mobility group AT-hook 1 | -0.0411093 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0403508 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0399711 |
| RPS24 | ribosomal protein S24 | -0.0383679 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0379459 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0367311 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0365931 |
| MAP1B | microtubule-associated protein 1B | -0.0365082 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0338839 |
| ANXA2 | annexin A2 | -0.0331738 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0325735 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0323639 |
| TMEM123 | transmembrane protein 123 | -0.03152 |
| RPS25 | ribosomal protein S25 | -0.0310373 |
| MYO1E | myosin IE | -0.0306342 |
| RPS23 | ribosomal protein S23 | -0.0306133 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | -0.0294259 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.029264 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0290809 |
| LDHA | lactate dehydrogenase A | -0.0288979 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0288555 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0288303 |
| ENO1 | enolase 1, (alpha) | -0.02842 |
| HMGB1 | high mobility group box 1 | -0.0282387 |
| NUP98 | nucleoporin 98kDa | -0.0271124 |
| INTS6 | integrator complex subunit 6 | -0.0267265 |
| CALR | calreticulin | -0.0266114 |
| POTEF | POTE ankyrin domain family, member F | -0.0259811 |
| RPS5 | ribosomal protein S5 | -0.0259704 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0242887 |
| TAPBP | TAP binding protein (tapasin) | -0.0242767 |
| FUS | FUS RNA binding protein | -0.0238217 |
| RPL8 | ribosomal protein L8 | -0.0237244 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0236203 |
| OSMR | oncostatin M receptor | -0.023519 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0231075 |
| RPL38 | ribosomal protein L38 | -0.022774 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0227053 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0226792 |
| RPS10 | ribosomal protein S10 | -0.0226309 |
| RPL34 | ribosomal protein L34 | -0.0225462 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0223765 |
| CCND1 | cyclin D1 | -0.0223372 |
| BRD2 | bromodomain containing 2 | -0.0222227 |
| MKI67 | marker of proliferation Ki-67 | -0.0221625 |
| HLA-B | major histocompatibility complex, class I, B | -0.0219701 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0219363 |
| RPS15 | ribosomal protein S15 | -0.0216659 |
| CARS1 | cysteinyl-tRNA synthetase 1 | -0.0216315 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.0213825 |
| SAMD4B | sterile alpha motif domain containing 4B | -0.0212028 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0205426 |
| SQSTM1 | sequestosome 1 | -0.0205417 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0203371 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0202398 |
| RPLP2 | ribosomal protein, large, P2 | -0.0200076 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0194272 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0193955 |
| H1-0 | H1.0 linker histone | -0.0193741 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0192716 |
| UPP1 | uridine phosphorylase 1 | -0.0189452 |
| CD44 | CD44 molecule (Indian blood group) | -0.0187618 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0187177 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.01869 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0186865 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0183682 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0183285 |
| RPS13 | ribosomal protein S13 | -0.0183113 |
| RPS19 | ribosomal protein S19 | -0.0181897 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0181625 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0179676 |
| TPM1 | tropomyosin 1 (alpha) | -0.0179611 |
| RPS14 | ribosomal protein S14 | -0.0178138 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0177325 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0174552 |
