| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pravastatin (sodium)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.133762 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.120113 |
| RPS12 | ribosomal protein S12 | 0.110073 |
| FRMD4A | FERM domain containing 4A | 0.109461 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.10625 |
| NAV3 | neuron navigator 3 | 0.0951601 |
| RPL37A | ribosomal protein L37a | 0.0903197 |
| RPS3 | ribosomal protein S3 | 0.0848726 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0846229 |
| STC1 | stanniocalcin 1 | 0.0782915 |
| SET | SET nuclear proto-oncogene | 0.0746434 |
| RPS6 | ribosomal protein S6 | 0.0676628 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0676012 |
| RPS8 | ribosomal protein S8 | 0.0593651 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0584262 |
| LAMB3 | laminin, beta 3 | 0.0563645 |
| WDR43 | WD repeat domain 43 | 0.0559692 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0559073 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0546613 |
| TPD52 | tumor protein D52 | 0.0545007 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0541917 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0527095 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0519274 |
| DGKI | diacylglycerol kinase, iota | 0.051575 |
| BBX | bobby sox homolog (Drosophila) | 0.0511584 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0507389 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0506623 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.04903 |
| FLNB | filamin B, beta | 0.0485336 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0482363 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.048027 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0477908 |
| RPS17 | ribosomal protein S17 | 0.0469882 |
| HDAC9 | histone deacetylase 9 | 0.0466922 |
| UPP1 | uridine phosphorylase 1 | 0.0459707 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 0.0455013 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0453771 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0447921 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0439721 |
| S100A2 | S100 calcium binding protein A2 | 0.0429326 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.042347 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0413776 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.040437 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | 0.0403518 |
| RPL30 | ribosomal protein L30 | 0.0401012 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0396306 |
| OGA | O-GlcNAcase | 0.0395035 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0392938 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0389627 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0381941 |
| RASA2 | RAS p21 protein activator 2 | 0.0380939 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0378383 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.037728 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0372487 |
| NAV2 | neuron navigator 2 | 0.037234 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0369372 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0368218 |
| ANO6 | anoctamin 6 | 0.0364413 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0364347 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0359925 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0356871 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0352016 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0350609 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0349047 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0348792 |
| SBF2 | SET binding factor 2 | 0.0347714 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.034164 |
| RPL5 | ribosomal protein L5 | 0.0336967 |
| RPL18 | ribosomal protein L18 | 0.0334645 |
| ARFGEF3 | ARFGEF family member 3 | 0.0333661 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.0332256 |
| SNX9 | sorting nexin 9 | 0.0330891 |
| YEATS2 | YEATS domain containing 2 | 0.0327305 |
| RLF | rearranged L-myc fusion | 0.0325119 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0324878 |
| HMGA2 | high mobility group AT-hook 2 | 0.0324682 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0324048 |
| RPS27A | ribosomal protein S27a | 0.0323937 |
| RUNX1 | runt-related transcription factor 1 | 0.0320517 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0319489 |
| VIM | vimentin | 0.0318237 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0318163 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0315387 |
| DST | dystonin | 0.0312042 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0309149 |
| DENND4C | DENN/MADD domain containing 4C | 0.0308367 |
| FOXJ3 | forkhead box J3 | 0.0307723 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0307703 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0305214 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0303223 |
| CAPRIN2 | caprin family member 2 | 0.0302985 |
| PTEN | phosphatase and tensin homolog | 0.0302006 |
| PGK1 | phosphoglycerate kinase 1 | 0.0300202 |
| SMYD3 | SET and MYND domain containing 3 | 0.029963 |
| OXR1 | oxidation resistance 1 | 0.0297158 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0295689 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0295032 |
| RBM26 | RNA binding motif protein 26 | 0.0293108 |
| AFDN | afadin, adherens junction formation factor | 0.02924 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.0292003 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.182283 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.156362 |
| ACTG1 | actin gamma 1 | -0.146495 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.132426 |
| EGR1 | early growth response 1 | -0.0886412 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0753463 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0731643 |
| HMGA1 | high mobility group AT-hook 1 | -0.0694548 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0646333 |
| SP100 | SP100 nuclear antigen | -0.0637423 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0632405 |
| NABP1 | nucleic acid binding protein 1 | -0.0618123 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0597121 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0584744 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0571866 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.056757 |
| SGMS2 | sphingomyelin synthase 2 | -0.0540725 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0527614 |
| FRMD6 | FERM domain containing 6 | -0.0511263 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0508734 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0493633 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0484726 |
| RPLP0 | ribosomal protein, large, P0 | -0.046234 |
| MT2A | metallothionein 2A | -0.0454878 |
| RPL8 | ribosomal protein L8 | -0.043628 |
| RPS15 | ribosomal protein S15 | -0.0428196 |
| INTS6 | integrator complex subunit 6 | -0.0422641 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0413804 |
| JMJD1C | jumonji domain containing 1C | -0.0412681 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0402717 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0402667 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0401526 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0396677 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0395847 |
| RPL12 | ribosomal protein L12 | -0.0393314 |
| MX1 | MX dynamin-like GTPase 1 | -0.0385304 |
| ERBIN | erbb2 interacting protein | -0.0383726 |
| HLA-C | major histocompatibility complex, class I, C | -0.0382253 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0381616 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0379276 |
| FUS | FUS RNA binding protein | -0.0371074 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.035586 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0352236 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.035039 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0346713 |
| RIGI | RNA sensor RIG-I | -0.0344726 |
| IL6ST | interleukin 6 signal transducer | -0.0343153 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0326001 |
| AHNAK | AHNAK nucleoprotein | -0.0324794 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0324053 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0319575 |
| ANXA2 | annexin A2 | -0.0294496 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0294118 |
| EMP1 | epithelial membrane protein 1 | -0.029171 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.028529 |
| RPS11 | ribosomal protein S11 | -0.0281871 |
| PKM | pyruvate kinase, muscle | -0.0281271 |
| ATF6 | activating transcription factor 6 | -0.027615 |
| CALR | calreticulin | -0.0275264 |
| MAP4 | microtubule-associated protein 4 | -0.0274903 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0271751 |
| ADAR | adenosine deaminase, RNA-specific | -0.0271614 |
| PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | -0.0270272 |
| DIAPH3 | diaphanous-related formin 3 | -0.02676 |
| CUL1 | cullin 1 | -0.0265113 |
| ATXN2L | ataxin 2-like | -0.0264593 |
| JUN | jun proto-oncogene | -0.0262894 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0261438 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0261103 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0258091 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0251928 |
| CDK17 | cyclin-dependent kinase 17 | -0.0245899 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0245665 |
| PLSCR1 | phospholipid scramblase 1 | -0.0242681 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0240265 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0239573 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0238526 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0236232 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0233787 |
| RPS5 | ribosomal protein S5 | -0.0233443 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0230558 |
| DGKH | diacylglycerol kinase, eta | -0.0229088 |
| FOXN2 | forkhead box N2 | -0.0226965 |
| HSF1 | heat shock transcription factor 1 | -0.0223746 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0222483 |
| LDHA | lactate dehydrogenase A | -0.0219764 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0216835 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0216628 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0216271 |
| RCOR1 | REST corepressor 1 | -0.0216269 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0214445 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.021405 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0213214 |
| LAP3 | leucine aminopeptidase 3 | -0.0212348 |
| ARF1 | ADP-ribosylation factor 1 | -0.0211197 |
| PMP22 | peripheral myelin protein 22 | -0.0209779 |
| GLG1 | golgi glycoprotein 1 | -0.0209452 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0207189 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0206437 |
| ZZZ3 | zinc finger, ZZ-type containing 3 | -0.0203441 |
