| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pravastatin (sodium)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.212258 |
| FNDC3B | fibronectin type III domain containing 3B | 0.135765 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.124747 |
| STC1 | stanniocalcin 1 | 0.0967999 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0954419 |
| CD109 | CD109 molecule | 0.0849127 |
| B2M | beta-2-microglobulin | 0.0766807 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0561188 |
| CENPF | centromere protein F, 350/400kDa | 0.0553558 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0551586 |
| POTEF | POTE ankyrin domain family, member F | 0.0543953 |
| YEATS2 | YEATS domain containing 2 | 0.0536136 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0518908 |
| MSN | moesin | 0.0480808 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0463173 |
| PCBP2 | poly(rC) binding protein 2 | 0.0460501 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0458383 |
| VEGFA | vascular endothelial growth factor A | 0.0451893 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0434799 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0426998 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0416585 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0413733 |
| HDGF | hepatoma-derived growth factor | 0.0411929 |
| ATP13A3 | ATPase type 13A3 | 0.0411183 |
| NBAS | neuroblastoma amplified sequence | 0.0408231 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0404323 |
| FAM13A | family with sequence similarity 13, member A | 0.0400108 |
| BBX | bobby sox homolog (Drosophila) | 0.0394997 |
| RPS12 | ribosomal protein S12 | 0.039058 |
| ZNF292 | zinc finger protein 292 | 0.0390311 |
| NUP58 | nucleoporin 58 | 0.0379839 |
| RPL5 | ribosomal protein L5 | 0.0373812 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0373433 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0371301 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0370448 |
| NCKAP1 | NCK-associated protein 1 | 0.036786 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0366306 |
| SEPTIN7 | septin 7 | 0.036562 |
| RPS8 | ribosomal protein S8 | 0.0357706 |
| SRP54 | signal recognition particle 54kDa | 0.0350338 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0344425 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0339813 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0339044 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0338048 |
| SETD5 | SET domain containing 5 | 0.0337385 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0336424 |
| NAV2 | neuron navigator 2 | 0.0330341 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0325048 |
| CBX3 | chromobox homolog 3 | 0.0323749 |
| NOP58 | NOP58 ribonucleoprotein | 0.0322419 |
| FMNL2 | formin-like 2 | 0.0322249 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0320129 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0315434 |
| LMNA | lamin A/C | 0.0312608 |
| NGLY1 | N-glycanase 1 | 0.0312534 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.03118 |
| CDH13 | cadherin 13 | 0.0309901 |
| SNX1 | sorting nexin 1 | 0.0309713 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.030875 |
| COPA | coatomer protein complex, subunit alpha | 0.030759 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0306338 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0305257 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0305216 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0302287 |
| MMP12 | matrix metallopeptidase 12 | 0.0299161 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0297974 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0296877 |
| RBM39 | RNA binding motif protein 39 | 0.0294741 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0294658 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0292382 |
| COL5A1 | collagen, type V, alpha 1 | 0.0292008 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0291614 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0290984 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0288798 |
| OPTN | optineurin | 0.0288747 |
| XPO1 | exportin 1 | 0.0286445 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.028366 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0281987 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0278232 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0277771 |
| AXL | AXL receptor tyrosine kinase | 0.0277176 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0276769 |
| RPS17 | ribosomal protein S17 | 0.0275247 |
| HDAC9 | histone deacetylase 9 | 0.0273644 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0273627 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0273003 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.026969 |
| ZNF148 | zinc finger protein 148 | 0.0269258 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0268475 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0267637 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0267454 |
| INSIG2 | insulin induced gene 2 | 0.026665 |
| RPS3 | ribosomal protein S3 | 0.0265198 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0263258 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0260948 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0259307 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | 0.0257943 |
| RPL37A | ribosomal protein L37a | 0.0256229 |
| GOLGA4 | golgin A4 | 0.0256124 |
| CDK19 | cyclin-dependent kinase 19 | 0.0255865 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.324584 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.150109 |
| FN1 | fibronectin 1 | -0.147651 |
| CD44 | CD44 molecule (Indian blood group) | -0.100348 |
| FRMD4A | FERM domain containing 4A | -0.0773584 |
| FTL | ferritin, light polypeptide | -0.0707117 |
| H1-0 | H1.0 linker histone | -0.0665764 |
| HLA-B | major histocompatibility complex, class I, B | -0.059762 |
| TMSB10 | thymosin beta 10 | -0.0576441 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0568546 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0525243 |
| NRP1 | neuropilin 1 | -0.0508401 |
| COL1A1 | collagen, type I, alpha 1 | -0.0507988 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0505615 |
| PTMA | prothymosin, alpha | -0.0505214 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0503515 |
| HM13 | histocompatibility (minor) 13 | -0.0501838 |
| ACTG1 | actin gamma 1 | -0.0479231 |
| IER3 | immediate early response 3 | -0.0479008 |
| VCL | vinculin | -0.0473859 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0462447 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0430685 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0411916 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0396362 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0393636 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0391534 |
| S100A10 | S100 calcium binding protein A10 | -0.0384659 |
| HPCAL1 | hippocalcin-like 1 | -0.0383252 |
| AHNAK | AHNAK nucleoprotein | -0.0354836 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0351441 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.035113 |
| NF1 | neurofibromin 1 | -0.034763 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0345486 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0345139 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.034204 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0328572 |
| TNNC1 | troponin C type 1 (slow) | -0.0326044 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0325288 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0316693 |
| PCBP3 | poly(rC) binding protein 3 | -0.0316286 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0313696 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0312171 |
| PGK1 | phosphoglycerate kinase 1 | -0.0311142 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0309202 |
| RPL34 | ribosomal protein L34 | -0.0308115 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0307197 |
| ARF1 | ADP-ribosylation factor 1 | -0.0303383 |
| CTSB | cathepsin B | -0.0299095 |
| NDRG1 | N-myc downstream regulated 1 | -0.0292624 |
| MAP1B | microtubule-associated protein 1B | -0.0283211 |
| SVIL | supervillin | -0.0282807 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.027612 |
| CANX | calnexin | -0.0270016 |
| GLIS3 | GLIS family zinc finger 3 | -0.0269952 |
| MAP4 | microtubule-associated protein 4 | -0.0269141 |
| GNAS | GNAS complex locus | -0.026812 |
| COL5A3 | collagen, type V, alpha 3 | -0.0262351 |
| PKM | pyruvate kinase, muscle | -0.0262195 |
| TKT | transketolase | -0.026153 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0261471 |
| TUBB | tubulin, beta class I | -0.0260947 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0259468 |
| CLIC4 | chloride intracellular channel 4 | -0.0257222 |
| RRBP1 | ribosome binding protein 1 | -0.025323 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0251676 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0251441 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0249579 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.02462 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0244931 |
| APP | amyloid beta (A4) precursor protein | -0.0244149 |
| CDK13 | cyclin-dependent kinase 13 | -0.0243149 |
| TGFBR1 | transforming growth factor, beta receptor 1 | -0.0239658 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.023699 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0236715 |
| CCDC47 | coiled-coil domain containing 47 | -0.0235424 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0231971 |
| XAF1 | XIAP associated factor 1 | -0.0231284 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0229048 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0228948 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0227057 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0226952 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0222468 |
| EGR1 | early growth response 1 | -0.0221466 |
| HMGA2 | high mobility group AT-hook 2 | -0.0221217 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0220122 |
| RSU1 | Ras suppressor protein 1 | -0.0219292 |
| ZNF217 | zinc finger protein 217 | -0.0218823 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0217055 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0216751 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0215332 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0213673 |
| RPL35A | ribosomal protein L35a | -0.0211065 |
| TSPAN9 | tetraspanin 9 | -0.0209589 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.02094 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0209298 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0208057 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.020562 |
| CAPNS1 | calpain, small subunit 1 | -0.0205393 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0204312 |
| ANXA2 | annexin A2 | -0.0202312 |
