| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pravastatin (sodium)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.124207 |
| NAV2 | neuron navigator 2 | 0.105625 |
| NLGN1 | neuroligin 1 | 0.0829648 |
| CENPF | centromere protein F, 350/400kDa | 0.077954 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0745624 |
| RPS3 | ribosomal protein S3 | 0.071567 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0622545 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0610965 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.05777 |
| NOTCH2 | notch 2 | 0.0544686 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0540854 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0517313 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0504804 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0489725 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0489672 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0484153 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0464997 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0448332 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0446033 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0442294 |
| RBM6 | RNA binding motif protein 6 | 0.043648 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0429281 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0424265 |
| VMP1 | vacuole membrane protein 1 | 0.0403918 |
| MSI2 | musashi RNA-binding protein 2 | 0.0403027 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0398679 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0384005 |
| NGLY1 | N-glycanase 1 | 0.0379326 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0375211 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.037459 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0369715 |
| PTK2 | protein tyrosine kinase 2 | 0.0364326 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0358343 |
| CLEC2D | C-type lectin domain family 2, member D | 0.0357352 |
| PRELID2 | PRELI domain containing 2 | 0.035028 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0349493 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0348142 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0345248 |
| ATXN1 | ataxin 1 | 0.0341047 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0340325 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0335841 |
| FAM13A | family with sequence similarity 13, member A | 0.0327233 |
| SEPTIN9 | septin 9 | 0.0323203 |
| TUSC3 | tumor suppressor candidate 3 | 0.0320932 |
| CD109 | CD109 molecule | 0.0303787 |
| NCKAP1 | NCK-associated protein 1 | 0.0298038 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0297395 |
| GPR137B | G protein-coupled receptor 137B | 0.0294634 |
| PCBP2 | poly(rC) binding protein 2 | 0.0293037 |
| MSN | moesin | 0.0292038 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0284994 |
| GOLGA4 | golgin A4 | 0.0281605 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0280642 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0278508 |
| MCL1 | myeloid cell leukemia 1 | 0.0272193 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0263322 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0261757 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0260309 |
| FLNB | filamin B, beta | 0.0259775 |
| SMAD3 | SMAD family member 3 | 0.0259424 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0259228 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0257545 |
| SRPK2 | SRSF protein kinase 2 | 0.0257011 |
| ANO6 | anoctamin 6 | 0.0256638 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0255863 |
| MMP12 | matrix metallopeptidase 12 | 0.0254576 |
| RPS12 | ribosomal protein S12 | 0.0254435 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0253739 |
| CTBP2 | C-terminal binding protein 2 | 0.0252917 |
| THOC2 | THO complex 2 | 0.025038 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0246327 |
| PIK3C3 | phosphatidylinositol 3-kinase, catalytic subunit type 3 | 0.0245193 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0242113 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0241421 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0241264 |
| MOSMO | modulator of smoothened | 0.0240898 |
| CEP250 | centrosomal protein 250kDa | 0.023791 |
| SBF2 | SET binding factor 2 | 0.0236776 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0236654 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.02365 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0234928 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0234027 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0233776 |
| CEP170 | centrosomal protein 170kDa | 0.0232244 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0232205 |
| EXOC6B | exocyst complex component 6B | 0.0231739 |
| GPHN | gephyrin | 0.0230435 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.023015 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0229354 |
| NBAS | neuroblastoma amplified sequence | 0.0228105 |
| MT2A | metallothionein 2A | 0.0228003 |
| RAI1 | retinoic acid induced 1 | 0.0227292 |
| ATP13A3 | ATPase type 13A3 | 0.0225918 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0225196 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0224505 |
| RASAL2 | RAS protein activator like 2 | 0.0223148 |
| ACTN1 | actinin, alpha 1 | 0.0221746 |
| KAZN | kazrin, periplakin interacting protein | 0.0221263 |
| CSNK1G1 | casein kinase 1, gamma 1 | 0.0220834 |
| AFDN | afadin, adherens junction formation factor | 0.0220149 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.242878 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.199055 |
| FMN1 | formin 1 | -0.108559 |
| FRMD4A | FERM domain containing 4A | -0.0966433 |
| LSAMP | limbic system-associated membrane protein | -0.086876 |
| NRG3 | neuregulin 3 | -0.0854968 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0768564 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0720368 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0692579 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0671902 |
| NDRG1 | N-myc downstream regulated 1 | -0.0643206 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0627044 |
| PGK1 | phosphoglycerate kinase 1 | -0.0615767 |
| TMSB10 | thymosin beta 10 | -0.0612064 |
| FHIT | fragile histidine triad | -0.0605579 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0552 |
| FN1 | fibronectin 1 | -0.0547256 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0538275 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.053554 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.053527 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0505087 |
| FTL | ferritin, light polypeptide | -0.0504778 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.050353 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.049089 |
| HMGA1 | high mobility group AT-hook 1 | -0.048983 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0486692 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0486531 |
| CANX | calnexin | -0.0463941 |
| PKM | pyruvate kinase, muscle | -0.0457002 |
| RPLP1 | ribosomal protein, large, P1 | -0.0441868 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0433467 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.043313 |
| MAP4 | microtubule-associated protein 4 | -0.0430383 |
| LDHA | lactate dehydrogenase A | -0.0409683 |
| ENO1 | enolase 1, (alpha) | -0.0409229 |
| CCND1 | cyclin D1 | -0.0409042 |
| ACTG1 | actin gamma 1 | -0.0405876 |
| HLA-B | major histocompatibility complex, class I, B | -0.0399701 |
| TKT | transketolase | -0.0383611 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0383429 |
| RPL35A | ribosomal protein L35a | -0.0381781 |
| SQSTM1 | sequestosome 1 | -0.0381109 |
| RPL38 | ribosomal protein L38 | -0.0356995 |
| APOD | apolipoprotein D | -0.0355034 |
| CADM1 | cell adhesion molecule 1 | -0.0350539 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0348238 |
| RRBP1 | ribosome binding protein 1 | -0.0347195 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0335353 |
| PMEL | premelanosome protein | -0.0334548 |
| CALR | calreticulin | -0.0331435 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0330964 |
| LMNA | lamin A/C | -0.033096 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0330617 |
| RHEB | Ras homolog enriched in brain | -0.0328585 |
| ARF1 | ADP-ribosylation factor 1 | -0.0325342 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0321683 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0321592 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0307123 |
| PRAME | preferentially expressed antigen in melanoma | -0.0307062 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0299145 |
| CDK6 | cyclin-dependent kinase 6 | -0.0298021 |
| MATR3 | matrin 3 | -0.0295433 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0292462 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0292372 |
| RPS15 | ribosomal protein S15 | -0.0289806 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0287693 |
| SP100 | SP100 nuclear antigen | -0.0286024 |
| RIGI | RNA sensor RIG-I | -0.0285353 |
| RPL34 | ribosomal protein L34 | -0.028509 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | -0.0284978 |
| FRMD5 | FERM domain containing 5 | -0.0284017 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -0.0282102 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0281944 |
| ANXA2 | annexin A2 | -0.0281185 |
| TFRC | transferrin receptor | -0.0276991 |
| FOXO3 | forkhead box O3 | -0.0276434 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0276424 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0276207 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0275391 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0273582 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0271253 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0271141 |
| ATF4 | activating transcription factor 4 | -0.0269769 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.026561 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0262213 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0261007 |
| WDR45B | WD repeat domain 45B | -0.0259873 |
| TCF20 | transcription factor 20 (AR1) | -0.0259142 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0258974 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0257953 |
| RPS23 | ribosomal protein S23 | -0.0257066 |
| RBM39 | RNA binding motif protein 39 | -0.025693 |
| BSG | basigin (Ok blood group) | -0.025546 |
| KIAA1549L | KIAA1549-like | -0.0251375 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | -0.0250767 |
| CTSD | cathepsin D | -0.025059 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0248902 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0248803 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.024812 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0247052 |
