| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pravastatin (sodium)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.123117 |
| FLNB | filamin B, beta | 0.0850804 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0618226 |
| PYGB | phosphorylase, glycogen; brain | 0.0617723 |
| TMSB4X | thymosin beta 4, X-linked | 0.0587951 |
| RPS8 | ribosomal protein S8 | 0.0522087 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0477047 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0466978 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.04634 |
| ECT2 | epithelial cell transforming 2 | 0.0461041 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0460607 |
| RPS12 | ribosomal protein S12 | 0.0425571 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0423971 |
| SET | SET nuclear proto-oncogene | 0.042293 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0422488 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0420418 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0406827 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0392317 |
| HDGF | hepatoma-derived growth factor | 0.0381762 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0377075 |
| GOLGA4 | golgin A4 | 0.0362898 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0361656 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0356172 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0354177 |
| RPL26 | ribosomal protein L26 | 0.0353634 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0353567 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0353194 |
| RPS6 | ribosomal protein S6 | 0.03517 |
| VMP1 | vacuole membrane protein 1 | 0.0340599 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0337675 |
| SQSTM1 | sequestosome 1 | 0.0334767 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0333478 |
| TMEM41B | transmembrane protein 41B | 0.0331672 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0329093 |
| RPL37A | ribosomal protein L37a | 0.0325348 |
| CD47 | CD47 molecule | 0.0321456 |
| SERINC1 | serine incorporator 1 | 0.031857 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0310696 |
| RPS3 | ribosomal protein S3 | 0.0310071 |
| MYOF | myoferlin | 0.0307495 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0306808 |
| WDR43 | WD repeat domain 43 | 0.0306474 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0299135 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0299114 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0298897 |
| B2M | beta-2-microglobulin | 0.0297923 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0297159 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0293879 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0288332 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0285987 |
| RPL5 | ribosomal protein L5 | 0.0283872 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0281994 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0278424 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0272722 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0271575 |
| S100A6 | S100 calcium binding protein A6 | 0.0270377 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0269434 |
| TMF1 | TATA element modulatory factor 1 | 0.0268067 |
| RPS2 | ribosomal protein S2 | 0.0266009 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0262732 |
| PHF3 | PHD finger protein 3 | 0.0262235 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0258948 |
| THOC2 | THO complex 2 | 0.0258507 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0254975 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0254795 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0252038 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0250611 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0247932 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0246574 |
| RPL31 | ribosomal protein L31 | 0.0244288 |
| RBM25 | RNA binding motif protein 25 | 0.0241581 |
| RPL3 | ribosomal protein L3 | 0.0240972 |
| CASC3 | cancer susceptibility candidate 3 | 0.023823 |
| NCKAP1 | NCK-associated protein 1 | 0.0236468 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0232762 |
| RHBDD1 | rhomboid domain containing 1 | 0.0229899 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0228936 |
| ZNF292 | zinc finger protein 292 | 0.0228264 |
| NUP58 | nucleoporin 58 | 0.0226695 |
| DUSP4 | dual specificity phosphatase 4 | 0.022112 |
| USP24 | ubiquitin specific peptidase 24 | 0.0220621 |
| PCBP2 | poly(rC) binding protein 2 | 0.0220066 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0211912 |
| RNF145 | ring finger protein 145 | 0.0208474 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.020749 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.0207139 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0205947 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0205231 |
| LOXL3 | lysyl oxidase-like 3 | 0.0204386 |
| SLTM | SAFB-like, transcription modulator | 0.0204049 |
| NKTR | natural killer cell triggering receptor | 0.0203332 |
| TMEM65 | transmembrane protein 65 | 0.0201367 |
| PNN | pinin, desmosome associated protein | 0.0200613 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0199673 |
| ZNHIT6 | zinc finger, HIT-type containing 6 | 0.0196518 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0196239 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0195864 |
| ATP13A3 | ATPase type 13A3 | 0.0195058 |
| MYO5A | myosin VA (heavy chain 12, myoxin) | 0.019354 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0192809 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.586325 |
| ACTG1 | actin gamma 1 | -0.111386 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0701581 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0686745 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0671209 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0625251 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0519979 |
| RHOA | ras homolog family member A | -0.0471638 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0462665 |
| FOXP1 | forkhead box P1 | -0.046043 |
| RPL35A | ribosomal protein L35a | -0.0450586 |
| BMP10 | bone morphogenetic protein 10 | -0.044493 |
| PKM | pyruvate kinase, muscle | -0.0441969 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0438915 |
| RBM39 | RNA binding motif protein 39 | -0.0431049 |
| FUS | FUS RNA binding protein | -0.039133 |
| HDLBP | high density lipoprotein binding protein | -0.0371667 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0371094 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0369527 |
| RPL13A | ribosomal protein L13a | -0.0339401 |
| RPS23 | ribosomal protein S23 | -0.0335607 |
| RPL8 | ribosomal protein L8 | -0.0332448 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0329918 |
| RPL34 | ribosomal protein L34 | -0.0327936 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.03198 |
| RPLP0 | ribosomal protein, large, P0 | -0.0316411 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0313007 |
| PRDX2 | peroxiredoxin 2 | -0.0308337 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.030639 |
| RPS11 | ribosomal protein S11 | -0.0293484 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0291019 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0282354 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0279702 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0276422 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0275669 |
| RPS15 | ribosomal protein S15 | -0.027035 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0269936 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0265616 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0261509 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0259592 |
| PFN1 | profilin 1 | -0.0258893 |
| RRBP1 | ribosome binding protein 1 | -0.0258835 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0254757 |
| CCND1 | cyclin D1 | -0.0254158 |
| RIGI | RNA sensor RIG-I | -0.0253258 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0249044 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0246723 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.024662 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.024192 |
| SP100 | SP100 nuclear antigen | -0.0236056 |
| RPL32 | ribosomal protein L32 | -0.0235082 |
| RPL19 | ribosomal protein L19 | -0.0231217 |
| RPL12 | ribosomal protein L12 | -0.0230618 |
| S100A10 | S100 calcium binding protein A10 | -0.0227013 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0226423 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.0222276 |
| RPS19 | ribosomal protein S19 | -0.022032 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0215645 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | -0.0215495 |
| HMGA1 | high mobility group AT-hook 1 | -0.0215355 |
| LDHA | lactate dehydrogenase A | -0.0214481 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0211266 |
| PDGFC | platelet derived growth factor C | -0.0209681 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0208259 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.0207911 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0205559 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0203342 |
| HMGB1 | high mobility group box 1 | -0.0203199 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0202641 |
| SEPTIN11 | septin 11 | -0.0201984 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0201472 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0200927 |
| CALR | calreticulin | -0.0200241 |
| RPL27A | ribosomal protein L27a | -0.0199705 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0199412 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0195789 |
| IL6ST | interleukin 6 signal transducer | -0.0195472 |
| TXNIP | thioredoxin interacting protein | -0.0193594 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0191591 |
| CANX | calnexin | -0.0187826 |
| PGK1 | phosphoglycerate kinase 1 | -0.0186758 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0186168 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0186092 |
| RPL21 | ribosomal protein L21 | -0.0185519 |
| MKI67 | marker of proliferation Ki-67 | -0.0184338 |
| CALU | calumenin | -0.0182023 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0181898 |
| JUN | jun proto-oncogene | -0.0181326 |
| HSPA4L | heat shock 70kDa protein 4-like | -0.0180514 |
| RPS21 | ribosomal protein S21 | -0.0179919 |
| RPS16 | ribosomal protein S16 | -0.0179884 |
| TUBB | tubulin, beta class I | -0.0179752 |
| TMSB10 | thymosin beta 10 | -0.0179284 |
| POTEF | POTE ankyrin domain family, member F | -0.0179217 |
| RPL7A | ribosomal protein L7a | -0.0178841 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0178755 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0177625 |
| RPLP2 | ribosomal protein, large, P2 | -0.0177532 |
| DIAPH2 | diaphanous-related formin 2 | -0.0174676 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0174516 |
