| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pravastatin (sodium)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.183577 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.131458 |
| NAV2 | neuron navigator 2 | 0.127495 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.122969 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0955097 |
| PDE10A | phosphodiesterase 10A | 0.0882812 |
| RPS12 | ribosomal protein S12 | 0.0820078 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0774566 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0734036 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0726756 |
| GOLGA4 | golgin A4 | 0.0663011 |
| DST | dystonin | 0.0623969 |
| RPS8 | ribosomal protein S8 | 0.0616752 |
| RPS6 | ribosomal protein S6 | 0.0613779 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0599145 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0598893 |
| OGA | O-GlcNAcase | 0.0589016 |
| MYOF | myoferlin | 0.0588631 |
| VIM | vimentin | 0.0586725 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0566103 |
| RPL37A | ribosomal protein L37a | 0.0561477 |
| SRGN | serglycin | 0.0556428 |
| SMYD3 | SET and MYND domain containing 3 | 0.0523614 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0493481 |
| CDK19 | cyclin-dependent kinase 19 | 0.0487467 |
| RPS3 | ribosomal protein S3 | 0.0468195 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0463369 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0457308 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0449421 |
| SERINC1 | serine incorporator 1 | 0.044819 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0438098 |
| CENPF | centromere protein F, 350/400kDa | 0.0431204 |
| PRELID2 | PRELI domain containing 2 | 0.0424693 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0423065 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0408336 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.040047 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.039691 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.039574 |
| ZNF292 | zinc finger protein 292 | 0.0380083 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0378581 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0376545 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0376456 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0375954 |
| PTMA | prothymosin, alpha | 0.036667 |
| RPL26 | ribosomal protein L26 | 0.0365459 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0358203 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0357616 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0356548 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0352218 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0351517 |
| SBF2 | SET binding factor 2 | 0.03497 |
| FLNB | filamin B, beta | 0.0349578 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0349065 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0349014 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0348728 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0348316 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0348269 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0348177 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0342583 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0341568 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0341074 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0339274 |
| FMNL2 | formin-like 2 | 0.0333417 |
| ARRDC3 | arrestin domain containing 3 | 0.0329927 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0328463 |
| TMSB4X | thymosin beta 4, X-linked | 0.0328081 |
| NGLY1 | N-glycanase 1 | 0.0327202 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0317638 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.031253 |
| ATXN1 | ataxin 1 | 0.0308217 |
| RPL9 | ribosomal protein L9 | 0.0306243 |
| NCKAP1 | NCK-associated protein 1 | 0.0306147 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.030441 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0298232 |
| ANXA5 | annexin A5 | 0.0297583 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.02932 |
| RAI1 | retinoic acid induced 1 | 0.0290293 |
| DIAPH3 | diaphanous-related formin 3 | 0.0287635 |
| RPL23 | ribosomal protein L23 | 0.0284694 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0284188 |
| TPM4 | tropomyosin 4 | 0.0281174 |
| THOC2 | THO complex 2 | 0.0280371 |
| CDH13 | cadherin 13 | 0.0278418 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0276222 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0275616 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0275063 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0273486 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0270923 |
| PFKP | phosphofructokinase, platelet | 0.0270658 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0270045 |
| ATP13A3 | ATPase type 13A3 | 0.0265234 |
| SFXN1 | sideroflexin 1 | 0.0264585 |
| CREBRF | CREB3 regulatory factor | 0.0262365 |
| TPM1 | tropomyosin 1 (alpha) | 0.026097 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0260694 |
| RPS2 | ribosomal protein S2 | 0.0259039 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0258252 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0258088 |
| SRP54 | signal recognition particle 54kDa | 0.0258021 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0256274 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.356005 |
| FN1 | fibronectin 1 | -0.174302 |
| VCL | vinculin | -0.145575 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.117339 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.110159 |
| IER3 | immediate early response 3 | -0.100911 |
| FTL | ferritin, light polypeptide | -0.0980759 |
| EGR1 | early growth response 1 | -0.0953471 |
| GLIS3 | GLIS family zinc finger 3 | -0.0874442 |
| TMSB10 | thymosin beta 10 | -0.0797413 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0717387 |
| BICC1 | BicC family RNA binding protein 1 | -0.0700227 |
| NABP1 | nucleic acid binding protein 1 | -0.0698499 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0656144 |
| LOC112694756 | uncharaterized LOC112694756 | -0.063703 |
| HLA-B | major histocompatibility complex, class I, B | -0.0612338 |
| KYNU | kynureninase | -0.0594525 |
| NDRG1 | N-myc downstream regulated 1 | -0.0592844 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0588439 |
| CTSD | cathepsin D | -0.0576209 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0529453 |
| LDHA | lactate dehydrogenase A | -0.0520281 |
| LOX | lysyl oxidase | -0.0510964 |
| PALLD | palladin, cytoskeletal associated protein | -0.0492612 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0483544 |
| HMGA2 | high mobility group AT-hook 2 | -0.0481311 |
| RIGI | RNA sensor RIG-I | -0.0480483 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0479922 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0471483 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0464128 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0451073 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0450008 |
| AHNAK | AHNAK nucleoprotein | -0.0446563 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0444734 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0440247 |
| HLA-A | major histocompatibility complex, class I, A | -0.0434869 |
| INTS6 | integrator complex subunit 6 | -0.0427926 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0425575 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0409488 |
| ANXA2 | annexin A2 | -0.0389812 |
| CD44 | CD44 molecule (Indian blood group) | -0.0383673 |
| QKI | QKI, KH domain containing, RNA binding | -0.0371113 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0368223 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0367051 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0352541 |
| UBC | ubiquitin C | -0.034621 |
| TXNIP | thioredoxin interacting protein | -0.0345666 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.034092 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0340213 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0338461 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.033393 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0333521 |
| PLIN2 | perilipin 2 | -0.032975 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0329124 |
| CLIC4 | chloride intracellular channel 4 | -0.0323967 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0320309 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0317618 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0316683 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.031517 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0314926 |
| C3 | complement component 3 | -0.0308546 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0303029 |
| PGK1 | phosphoglycerate kinase 1 | -0.0301039 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0300154 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0298757 |
| CDK17 | cyclin-dependent kinase 17 | -0.0298158 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0285529 |
| PKM | pyruvate kinase, muscle | -0.0284507 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0284039 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0282773 |
| CANX | calnexin | -0.0281298 |
| WTAP | Wilms tumor 1 associated protein | -0.0280528 |
| ACTG1 | actin gamma 1 | -0.0280191 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0269527 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0267335 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.025659 |
| DIAPH2 | diaphanous-related formin 2 | -0.0254621 |
| NTN4 | netrin 4 | -0.0252574 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0249391 |
| RAB7A | RAB7A, member RAS oncogene family | -0.024768 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0246755 |
| SP100 | SP100 nuclear antigen | -0.024519 |
| CTSB | cathepsin B | -0.0244619 |
| GOPC | golgi-associated PDZ and coiled-coil motif containing | -0.0242935 |
| FRMD4A | FERM domain containing 4A | -0.0241768 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0240374 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0237152 |
| THBS2 | thrombospondin 2 | -0.0236314 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0232171 |
| TRIM55 | tripartite motif containing 55 | -0.0229462 |
| NFIL3 | nuclear factor, interleukin 3 regulated | -0.0223905 |
| GRN | granulin | -0.0222183 |
| PMP22 | peripheral myelin protein 22 | -0.0221406 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0221119 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0216106 |
| RYBP | RING1 and YY1 binding protein | -0.0213048 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0212755 |
| TUBB | tubulin, beta class I | -0.0211868 |
| WASF2 | WAS protein family, member 2 | -0.0209829 |
| OSMR | oncostatin M receptor | -0.0209111 |
