| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pravastatin (sodium) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pravastatin (sodium)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.111751 |
| B2M | beta-2-microglobulin | 0.100263 |
| ZNF292 | zinc finger protein 292 | 0.0896191 |
| PTMA | prothymosin, alpha | 0.0740433 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0655602 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0651684 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0578903 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0497468 |
| CALR | calreticulin | 0.0484362 |
| PGK1 | phosphoglycerate kinase 1 | 0.0480929 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0478 |
| PTK2 | protein tyrosine kinase 2 | 0.0471217 |
| AHNAK | AHNAK nucleoprotein | 0.0463829 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0430702 |
| FMNL2 | formin-like 2 | 0.0412312 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0408655 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0407886 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0395568 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0395305 |
| DENND4C | DENN/MADD domain containing 4C | 0.0390332 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0381444 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0372209 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0369195 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0367988 |
| ENO1 | enolase 1, (alpha) | 0.036316 |
| RPLP2 | ribosomal protein, large, P2 | 0.0361796 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0358993 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0349572 |
| CDC73 | cell division cycle 73 | 0.0339946 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0335342 |
| SEPTIN9 | septin 9 | 0.033067 |
| SBF2 | SET binding factor 2 | 0.0325075 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0321406 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0316271 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0314465 |
| RBM39 | RNA binding motif protein 39 | 0.0307392 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0301146 |
| COL5A1 | collagen, type V, alpha 1 | 0.0296967 |
| FRMD6 | FERM domain containing 6 | 0.0295653 |
| FN1 | fibronectin 1 | 0.0294279 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0293948 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0293895 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0293826 |
| NAV2 | neuron navigator 2 | 0.0289916 |
| RPLP1 | ribosomal protein, large, P1 | 0.0289694 |
| SMAD3 | SMAD family member 3 | 0.0289608 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.028864 |
| STK4 | serine/threonine kinase 4 | 0.0288219 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0281512 |
| RPS12 | ribosomal protein S12 | 0.0281206 |
| XPO1 | exportin 1 | 0.0280119 |
| HLA-B | major histocompatibility complex, class I, B | 0.0278721 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0277223 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0276532 |
| RPL7 | ribosomal protein L7 | 0.0273973 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0270536 |
| PRSS23 | protease, serine, 23 | 0.0270484 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.027046 |
| PARD3 | par-3 family cell polarity regulator | 0.0269931 |
| RORA | RAR-related orphan receptor A | 0.0269868 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0266416 |
| OGA | O-GlcNAcase | 0.0265939 |
| CYRIB | CYFIP related Rac1 interactor B | 0.0263137 |
| PRELID2 | PRELI domain containing 2 | 0.0262297 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0259944 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0259585 |
| DST | dystonin | 0.0258329 |
| STAG2 | stromal antigen 2 | 0.0257105 |
| ATP13A3 | ATPase type 13A3 | 0.0255978 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0255058 |
| RPL36 | ribosomal protein L36 | 0.0252167 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0251399 |
| RPL30 | ribosomal protein L30 | 0.0251016 |
| FAM13A | family with sequence similarity 13, member A | 0.0250589 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.025056 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0250472 |
| WWOX | WW domain containing oxidoreductase | 0.0250065 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0248659 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0248445 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0248091 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0247179 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0246865 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0246154 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0245504 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.02444 |
| MATR3 | matrin 3 | 0.024296 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0242692 |
| RPS17 | ribosomal protein S17 | 0.0242649 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0242411 |
| FAM13B | family with sequence similarity 13, member B | 0.024128 |
| GPC6 | glypican 6 | 0.0240884 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0240474 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0240429 |
| DENND4A | DENN/MADD domain containing 4A | 0.0239314 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0237979 |
| MORF4L1 | mortality factor 4 like 1 | 0.0237221 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0235592 |
| RPS8 | ribosomal protein S8 | 0.0234565 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0234127 |
| YEATS2 | YEATS domain containing 2 | 0.0233877 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.26104 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.229416 |
| FTL | ferritin, light polypeptide | -0.119974 |
| MT2A | metallothionein 2A | -0.10919 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0894711 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.089105 |
| TMSB10 | thymosin beta 10 | -0.0867221 |
| POTEF | POTE ankyrin domain family, member F | -0.0828612 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0819476 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0784481 |
| EGFR | epidermal growth factor receptor | -0.0660512 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0647913 |
| HIP1 | huntingtin interacting protein 1 | -0.0601095 |
| NDRG1 | N-myc downstream regulated 1 | -0.059338 |
| MAP1B | microtubule-associated protein 1B | -0.0497912 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0460581 |
| VEGFA | vascular endothelial growth factor A | -0.0446466 |
| PKM | pyruvate kinase, muscle | -0.0423107 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0422604 |
| CDK6 | cyclin-dependent kinase 6 | -0.0421718 |
| CADM1 | cell adhesion molecule 1 | -0.0399259 |
| ASPH | aspartate beta-hydroxylase | -0.0394737 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0388129 |
| C1D | C1D nuclear receptor corepressor | -0.0382463 |
| COL1A1 | collagen, type I, alpha 1 | -0.0373608 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0368343 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0364377 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0356962 |
| ECE1 | endothelin converting enzyme 1 | -0.0350916 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0349886 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0342908 |
| DSTN | destrin (actin depolymerizing factor) | -0.03415 |
| GLG1 | golgi glycoprotein 1 | -0.0325904 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0324072 |
| COL1A2 | collagen, type I, alpha 2 | -0.0319509 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.031674 |
| LMNA | lamin A/C | -0.0315937 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0313845 |
| RAB31 | RAB31, member RAS oncogene family | -0.0310261 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0305749 |
| EGR1 | early growth response 1 | -0.0303656 |
| MSN | moesin | -0.0303084 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0299324 |
| CALU | calumenin | -0.0297818 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0296232 |
| HM13 | histocompatibility (minor) 13 | -0.0296057 |
| CD99 | CD99 molecule | -0.0291799 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0289559 |
| RLF | rearranged L-myc fusion | -0.028705 |
| RAP1A | RAP1A, member of RAS oncogene family | -0.0284625 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0283892 |
| TGFB1 | transforming growth factor, beta 1 | -0.028231 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.027982 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0278479 |
| HLA-A | major histocompatibility complex, class I, A | -0.0278336 |
| UBC | ubiquitin C | -0.0277821 |
| BCAR1 | breast cancer anti-estrogen resistance 1 | -0.0277333 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0272178 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0268729 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0266945 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0266443 |
| SCFD2 | sec1 family domain containing 2 | -0.0264515 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0263414 |
| ACTG1 | actin gamma 1 | -0.0262493 |
| UPP1 | uridine phosphorylase 1 | -0.0262106 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0254189 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0254145 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0254091 |
| ANKRD11 | ankyrin repeat domain 11 | -0.024762 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0247387 |
| NRXN3 | neurexin 3 | -0.0245455 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0244134 |
| TXNIP | thioredoxin interacting protein | -0.0243349 |
| DCAF10 | DDB1 and CUL4 associated factor 10 | -0.0242037 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0240573 |
| SMYD3 | SET and MYND domain containing 3 | -0.0239657 |
| RPL35A | ribosomal protein L35a | -0.023884 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0238643 |
| VCL | vinculin | -0.0238475 |
| CDH13 | cadherin 13 | -0.02383 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0234923 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.0233635 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0233124 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0232402 |
| CDK13 | cyclin-dependent kinase 13 | -0.023221 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0230748 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0229718 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0228259 |
| TSPAN9 | tetraspanin 9 | -0.0227811 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0227205 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | -0.0226872 |
| TAGLN2 | transgelin 2 | -0.022671 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0226709 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.022623 |
| SEPTIN7 | septin 7 | -0.0226058 |
| TPM4 | tropomyosin 4 | -0.0222328 |
| ARF4 | ADP-ribosylation factor 4 | -0.0221724 |
| WASF2 | WAS protein family, member 2 | -0.0221001 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0220906 |
| ADM | adrenomedullin | -0.0217216 |
